How far is Saint Leo, FL from Cape Coral, FL?
The driving distance from Saint Leo, FL to Cape Coral, FL is about 158.3 miles (254.7 km), with a travel time of about 02h 39m by car.
- The straight-line flight distance is about 124 miles (199.6 km).
- For a round trip, plan for roughly 05h 18m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 39m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Sarasota County, Florida
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Saint Leo and Cape Coral.
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Leo and Cape Coral.
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1
Start on the route
85 m · 24 sec
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2
Turn left
64 m · 17 sec
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3
Enter the roundabout and take exit 1 toward the route
17 m · 5 sec
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4
Exit the roundabout
85 m · 23 sec
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5
Turn right onto Old State Road 52
1.3 km · 1 min · Old State Road 52
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6
Enter the roundabout and take exit 3 toward Old State Road 52
56 m · 5 sec · Old State Road 52
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7
Exit the roundabout onto Old State Road 52
2.3 mi · 4 min · Old State Road 52
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8
Turn right onto McCabe Road
144 m · 9 sec · McCabe Road
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9
Continue on State Road 52
1.4 mi · 3 min · State Road 52
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10
Take the ramp sharp left toward FL 52: Dade City, New Port Richey
33 m · 3 sec
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11
Turn slight left onto State Road 52
95 m · 6 sec · State Road 52
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12
Take the ramp slight right toward I 75 South: Tampa, Saint Petersburg
3038 ft · 1 min
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13
Merge slight left
10.9 mi · 12 min
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14
Keep slight left to continue on South I 75: Naples
74.3 mi · 1 hr 20 min
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15
Keep slight left
42.2 mi · 45 min
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16
Take the exit slight right toward CR 762: North Fort Myers, Cape Coral
1532 ft · 37 sec
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17
Keep slight right to continue on CR 762 West, to US 41
859 ft · 21 sec
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18
Turn straight onto Tuckers Grade
1.4 km · 2 min · Tuckers Grade
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19
Turn left onto Tamiami Trail
10.4 mi · 13 min · Tamiami Trail
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20
Turn right onto Del Prado Boulevard North
6.5 mi · 11 min · Del Prado Boulevard North
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21
Continue on Del Prado Boulevard South
6.2 mi · 13 min · Del Prado Boulevard South
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22
Turn right onto Cape Coral Parkway East
1669 ft · 41 sec · Cape Coral Parkway East
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23
Turn right
61 m · 15 sec
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24
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Saint Leo and Cape Coral.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
South I 75
Keep slight left to continue on South I 75: Naples
74.3 mi · 01h 20m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving Saint Leo and Mostly Sunny near Cape Coral.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Saint Leo to Cape Coral?
The road trip is about 158.3 miles (254.7 km) and usually takes 02h 39m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
The Meadows is a useful midpoint, sitting about 79 miles from Saint Leo and 79.3 miles from Cape Coral.
How much longer is the road route than the straight-line distance?
The direct path is about 124 miles (199.6 km), while the road route adds roughly 34.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 1:12 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $23.15 one way or $46.29 round trip. Estimated CO2 is about 49.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Saint Leo and Mostly Sunny near Cape Coral.
Stop Ideas Near The Meadows
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to The Meadows.
Sarasota, Florida
Bradenton, Florida
Port Charlotte, Florida
St Petersburg-Pinellas Park-Clearwater, Florida
Flight Path Map
This map shows the direct air route between Saint Leo and Cape Coral. Straight-line distance: 124.05 mi (199.64 km).
#1 Saint Leo
Town of the United States
| Population | 1,372 |
| Coordinates | 28.3372300, -82.2584200 |
| Altitude | 57 |
| Country | United States |
#2 Cape Coral
The second most populous city in Lee County, Florida.
| Population | 200,972 |
| Coordinates | 26.5628500, -81.9495300 |
| Altitude | 1 |
| Country | United States |
End: (-81.94953, 26.562855)
Estimated Travel Time
Distance: 255 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 16m |
| 40 mph (64.37 km/h) | 03h 57m |
| 50 mph (80.47 km/h) | 03h 09m |
| 60 mph (96.56 km/h) | 02h 38m |
| 70 mph (112.65 km/h) | 02h 15m |
| 80 mph (129 km/h) | 01h 58m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $23.15 | $46.29 |
| Mid-grade | $4.60 | $25.65 | $51.29 |
| Premium | $4.90 | $27.32 | $54.64 |
| Diesel | $4.35 | $24.27 | $48.55 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 22, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.