How far is Port Saint Lucie, FL from Myrtle Grove, FL?
The driving distance from Port Saint Lucie, FL to Myrtle Grove, FL is about 569.3 miles (916.2 km), with a travel time of about 10h 20m by car.
- The straight-line flight distance is about 473 miles (761.3 km).
- For a round trip, plan for roughly 20h 40m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 10h 20m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat of Suwannee County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Partly Sunny
Driving Route Map
The map below follows the saved road route between Port Saint Lucie and Myrtle Grove.
Turn-by-Turn Driving Directions
Step-by-step road directions between Port Saint Lucie and Myrtle Grove.
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1
Start on Southwest Carter Avenue
66 m · 11 sec · Southwest Carter Avenue
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2
Turn right onto Southeast Airoso Boulevard
1.6 mi · 3 min · Southeast Airoso Boulevard
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3
Turn right onto Southwest Port Saint Lucie Boulevard
1.3 km · 1 min · Southwest Port Saint Lucie Boulevard
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4
Turn left onto Southwest Bayshore Boulevard
560 ft · 22 sec · Southwest Bayshore Boulevard
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5
Take the ramp straight toward Florida's Turnpike Toll
2787 ft · 1 min
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6
Keep slight right to continue on Orlando, Florida's Turnpike North
1842 ft · 45 sec
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7
Merge slight left onto Florida's Turnpike
164.8 mi · 2 hr 57 min · Florida's Turnpike
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8
Keep slight left to continue on Florida's Turnpike
1281 ft · 16 sec · Florida's Turnpike
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9
Merge slight left
106.9 mi · 1 hr 55 min
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10
Take the exit slight right toward I 10: Jacksonville, Tallahassee
820 ft · 16 sec
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11
Keep slight left to continue on I 10 West: Tallahassee
1569 ft · 30 sec
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12
Merge slight right
283.4 mi · 5 hr 4 min
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13
Take the exit slight right toward I 110 South: Pensacola, Pensacola Beach
1.4 km · 1 min
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14
Merge slight left onto Reubin O'Donovan Askew Parkway
2.7 mi · 3 min · Reubin O'Donovan Askew Parkway
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15
Take the exit slight right toward FL 295: Fairfield Drive
1615 ft · 39 sec
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16
Keep slight right to continue on FL 295 South
610 ft · 17 sec
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17
Turn straight onto East Fairfield Drive
2.9 mi · 6 min · East Fairfield Drive
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18
Continue on Fairfield Drive
1.6 mi · 3 min · Fairfield Drive
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19
Turn left onto North 57th Avenue
2274 ft · 1 min · North 57th Avenue
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20
Turn right onto Lillian Highway
1 mi · 2 min · Lillian Highway
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21
Turn right
13 m · 5 sec
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22
Turn right
25 m · 6 sec
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23
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Port Saint Lucie and Myrtle Grove.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 10 West
Merge slight right
283 mi · 05h 04m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Partly Sunny leaving Port Saint Lucie and Partly Sunny near Myrtle Grove.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Port Saint Lucie to Myrtle Grove?
The road trip is about 569.3 miles (916.2 km) and usually takes 10h 20m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Live Oak is a useful midpoint, sitting about 284.7 miles from Port Saint Lucie and 284.7 miles from Myrtle Grove.
How much longer is the road route than the straight-line distance?
The direct path is about 473 miles (761.3 km), while the road route adds roughly 96.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $83.33 one way or $166.67 round trip. Estimated CO2 is about 178.5 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Port Saint Lucie and Myrtle Grove, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Partly Sunny around Port Saint Lucie and Partly Sunny near Myrtle Grove.
Stop Ideas Near Live Oak
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Live Oak.
Gainesville, Florida
Waldo, Florida
Flight Path Map
This map shows the direct air route between Port Saint Lucie and Myrtle Grove. Straight-line distance: 473.06 mi (761.32 km).
#1 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
#2 Myrtle Grove
Census-designated place in Escambia County, Florida
| Population | 15,870 |
| Coordinates | 30.4210300, -87.3074700 |
| Altitude | 14 |
| Country | United States |
End: Myrtle Grove (-87.30747, 30.42103)
Estimated Travel Time
Distance: 916 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 18h 58m |
| 40 mph (64.37 km/h) | 14h 13m |
| 50 mph (80.47 km/h) | 11h 23m |
| 60 mph (96.56 km/h) | 09h 29m |
| 70 mph (112.65 km/h) | 08h 07m |
| 80 mph (129 km/h) | 07h 06m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $83.33 | $166.67 |
| Mid-grade | $4.60 | $92.33 | $184.67 |
| Premium | $4.90 | $98.36 | $196.72 |
| Diesel | $4.35 | $87.39 | $174.78 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.