How far is Port Saint Lucie, FL from Big Pine Key, FL?
The driving distance from Port Saint Lucie, FL to Big Pine Key, FL is about 243.5 miles (391.8 km), with a travel time of about 05h 15m by car.
- The straight-line flight distance is about 191.7 miles (308.5 km).
- For a round trip, plan for roughly 10h 30m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 15m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Miami-Dade County, Florida
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Partly Cloudy
Driving Route Map
The map below follows the saved road route between Port Saint Lucie and Big Pine Key.
Turn-by-Turn Driving Directions
Step-by-step road directions between Port Saint Lucie and Big Pine Key.
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1
Start on Southwest Carter Avenue
66 m · 11 sec · Southwest Carter Avenue
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2
Turn right onto Southeast Airoso Boulevard
1.6 mi · 3 min · Southeast Airoso Boulevard
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3
Turn right onto Southwest Port Saint Lucie Boulevard
1.3 km · 1 min · Southwest Port Saint Lucie Boulevard
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4
Turn left onto Southwest Bayshore Boulevard
560 ft · 22 sec · Southwest Bayshore Boulevard
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5
Take the ramp straight toward Florida's Turnpike Toll
2787 ft · 1 min
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6
Keep slight left to continue on Miami, Florida's Turnpike South
2780 ft · 1 min
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7
Merge slight left onto Florida's Turnpike
95.5 mi · 1 hr 46 min · Florida's Turnpike
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8
Take the exit slight right toward Florida's Turnpike Toll South, Homestead
1197 ft · 20 sec · Homestead Extension of Florida's Turnpike
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9
Keep slight left to continue on Homestead Extension of Florida's Turnpike
46.9 mi · 54 min · Homestead Extension of Florida's Turnpike
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10
Keep slight left
2930 ft · 1 min
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11
Merge slight left onto Dixie Highway
19.2 mi · 27 min · Dixie Highway
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12
Continue on Overseas Highway
77.4 mi · 2 hr · Overseas Highway
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13
Arrive at your destination
0 m · 1 sec · Overseas Highway
Car Route Details
A richer read on the saved driving route between Port Saint Lucie and Big Pine Key.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Florida's Turnpike
Merge slight left onto Florida's Turnpike
95.5 mi · 01h 46m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Port Saint Lucie and Partly Cloudy near Big Pine Key.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Port Saint Lucie to Big Pine Key?
The road trip is about 243.5 miles (391.8 km) and usually takes 05h 15m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Tamiami is a useful midpoint, sitting about 122 miles from Port Saint Lucie and 121.5 miles from Big Pine Key.
How much longer is the road route than the straight-line distance?
The direct path is about 191.7 miles (308.5 km), while the road route adds roughly 51.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:30 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.63 one way or $71.26 round trip. Estimated CO2 is about 76.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Port Saint Lucie and Partly Cloudy near Big Pine Key.
Stop Ideas Near Tamiami
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Basketball Court
Hialeah City Hall
Hialeah Gardens Community Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Tamiami.
Miami Intermodal Center
Hollywood
Fort Lauderdale
Deerfield Beach
Flight Path Map
This map shows the direct air route between Port Saint Lucie and Big Pine Key. Straight-line distance: 191.72 mi (308.54 km).
#1 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
#2 Big Pine Key
Census designated place
| Population | 4,252 |
| Coordinates | 24.6698700, -81.3539700 |
| Altitude | 1 |
| Country | United States |
End: Big Pine Key (-81.35397, 24.66987)
Estimated Travel Time
Distance: 392 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 06m |
| 40 mph (64.37 km/h) | 06h 05m |
| 50 mph (80.47 km/h) | 04h 52m |
| 60 mph (96.56 km/h) | 04h 03m |
| 70 mph (112.65 km/h) | 03h 28m |
| 80 mph (129 km/h) | 03h 02m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $35.63 | $71.26 |
| Mid-grade | $4.60 | $39.48 | $78.96 |
| Premium | $4.90 | $42.06 | $84.11 |
| Diesel | $4.35 | $37.37 | $74.73 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 07, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.