How far is Pikeville, KY from Henderson, KY?
The driving distance from Pikeville, KY to Henderson, KY is about 340.6 miles (548.2 km), with a travel time of about 05h 18m by car.
- The straight-line flight distance is about 278.4 miles (448.1 km).
- For a round trip, plan for roughly 10h 36m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 18m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat city in Franklin County, Kentucky, USA and Kentucky federated state capital city
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Fog then Partly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Pikeville and Henderson.
Turn-by-Turn Driving Directions
Step-by-step road directions between Pikeville and Henderson.
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1
Start on 2nd Street
35 m · 7 sec · 2nd Street
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2
Turn right onto Caroline Avenue
79 m · 13 sec · Caroline Avenue
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3
At the end of the road, turn right onto Hambley Boulevard
1.1 mi · 2 min · Hambley Boulevard
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4
Turn right onto Loraine Street
1017 ft · 24 sec · Loraine Street
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5
At the end of the road, turn left onto North Mayo Trail
2067 ft · 35 sec · North Mayo Trail
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6
Take the ramp slight right
902 ft · 25 sec
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7
Continue straight
12 mi · 14 min
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8
Continue straight
11.4 mi · 13 min
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9
Take the exit slight right
1942 ft · 55 sec
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10
Turn left
36.3 mi · 40 min
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11
Continue on Mountain Parkway
57 mi · 1 hr 1 min · Mountain Parkway
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12
Merge slight left
15.5 mi · 17 min
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13
Keep slight right to continue on I 64 West, I 75 North: Louisville, Cincinnati
6.9 mi · 8 min
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14
Keep slight left to continue on I 64 West: Frankfort, Louisville
73.5 mi · 1 hr 23 min
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15
Keep slight right
5.3 mi · 7 min
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16
Continue straight
90.4 mi · 1 hr 38 min
-
17
Take the exit slight right toward I 69 South, SR 57 South: Evansville, Henderson, Kentucky
1463 ft · 50 sec
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18
Merge slight left
20.1 mi · 23 min
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19
Take the exit slight right toward US 41: Vincennes, Henderson, Kentucky
884 ft · 17 sec
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20
Keep slight left to continue on US 41 South: Henderson, Kentucky
2455 ft · 47 sec
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21
Keep slight right to continue on US 41 South: Henderson, Kentucky
789 ft · 27 sec
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22
Keep slight right to continue on US 41 South: Henderson, Kentucky
1353 ft · 46 sec
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23
Merge slight left
6.1 mi · 9 min
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24
Take the exit slight right toward US 60 West, US 41 Alternate: Henderson
1305 ft · 36 sec
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25
Turn straight
1.6 mi · 4 min
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26
Turn left onto Washington Street
65 m · 11 sec · Washington Street
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27
Turn left
30 m · 7 sec
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28
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Pikeville and Henderson.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 64 West
Continue straight
90.4 mi · 01h 38m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Patchy Fog then Partly Sunny leaving Pikeville and Sunny near Henderson.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Pikeville to Henderson?
The road trip is about 340.6 miles (548.2 km) and usually takes 05h 18m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Frankfort is a useful midpoint, sitting about 169.8 miles from Pikeville and 170.9 miles from Henderson.
How much longer is the road route than the straight-line distance?
The direct path is about 278.4 miles (448.1 km), while the road route adds roughly 62.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:24 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $45.33 one way or $90.65 round trip. Estimated CO2 is about 106.8 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Pikeville and Henderson, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Patchy Fog then Partly Sunny around Pikeville and Sunny near Henderson.
Stop Ideas Near Frankfort
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Frankfort.
Louisville, Kentucky
Cincinnati Museum Center at Union Terminal
Cincinnati, OH
Maysville
Flight Path Map
This map shows the direct air route between Pikeville and Henderson. Straight-line distance: 278.45 mi (448.13 km).
#1 Pikeville
City and county seat of Pike County, Kentucky
| Population | 6,432 |
| Coordinates | 37.4792700, -82.5187600 |
| Altitude | 207 |
| Country | United States |
#2 Henderson
City in and county seat of Henderson County, Kentucky, United States
| Population | 27,974 |
| Coordinates | 37.8361500, -87.5900100 |
| Altitude | 124 |
| Country | United States |
End: (-87.590062, 37.836125)
Estimated Travel Time
Distance: 548 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 21m |
| 40 mph (64.37 km/h) | 08h 31m |
| 50 mph (80.47 km/h) | 06h 48m |
| 60 mph (96.56 km/h) | 05h 40m |
| 70 mph (112.65 km/h) | 04h 52m |
| 80 mph (129 km/h) | 04h 14m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $45.33 | $90.65 |
| Mid-grade | $4.25 | $51.12 | $102.24 |
| Premium | $4.65 | $55.94 | $111.88 |
| Diesel | $5.30 | $63.75 | $127.51 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Kentucky · May 07, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.