How far is Henderson, KY from Pikeville, KY?
The driving distance from Henderson, KY to Pikeville, KY is about 339.1 miles (545.8 km), with a travel time of about 06h 24m by car.
- The straight-line flight distance is about 278.4 miles (448.1 km).
- For a round trip, plan for roughly 12h 48m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 24m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat city in Franklin County, Kentucky, USA and Kentucky federated state capital city
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Fog then Partly Sunny
Driving Route Map
The map below follows the saved road route between Henderson and Pikeville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Henderson and Pikeville.
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1
Start on the route
30 m · 9 sec
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2
Turn right onto Washington Street
65 m · 10 sec · Washington Street
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3
Turn right onto South Green Street
1.6 mi · 4 min · South Green Street
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4
Take the ramp straight toward US 41: Evansville, Madisonville
748 ft · 21 sec
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5
Keep slight left to continue on US 41 North: Evansville
2451 ft · 1 min
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6
Merge slight left
5.3 mi · 8 min
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7
Take the exit slight right toward I 69 North
1008 ft · 17 sec
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8
Keep slight right to continue on I 69 North
1.2 km · 1 min
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9
Merge slight left
20 mi · 23 min
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10
Take the exit slight right toward I 64 East: Louisville
3069 ft · 58 sec
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11
Merge slight left
91.7 mi · 1 hr 40 min
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12
Keep slight right
83.1 mi · 1 hr 35 min
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13
Take the exit slight left toward I 64 East: Winchester, Ashland
16.6 mi · 19 min
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14
Keep slight right to continue on Mountain Parkway
81.7 mi · 1 hr 28 min · Mountain Parkway
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15
Continue on Old Middle Creek Road
11.1 mi · 13 min · Old Middle Creek Road
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16
Take the exit slight right
1575 ft · 43 sec
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17
Merge slight left
23.5 mi · 27 min
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18
Turn right
67 m · 7 sec
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19
At the end of the road, turn left onto North Mayo Trail
1.1 km · 60 sec · North Mayo Trail
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20
Turn right onto Loraine Street
924 ft · 23 sec · Loraine Street
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21
Turn left onto Hambley Boulevard
1.1 mi · 2 min · Hambley Boulevard
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22
Turn left onto Division Street
82 m · 9 sec · Division Street
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23
Turn right onto 2nd Street
94 m · 9 sec · 2nd Street
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24
Arrive at your destination
0 m · 1 sec · 2nd Street
Car Route Details
A richer read on the saved driving route between Henderson and Pikeville.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 64 East
Merge slight left
91.7 mi · 01h 40m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving Henderson and Patchy Fog then Partly Sunny near Pikeville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Henderson to Pikeville?
The road trip is about 339.1 miles (545.8 km) and usually takes 06h 24m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Frankfort is a useful midpoint, sitting about 169.3 miles from Henderson and 169.8 miles from Pikeville.
How much longer is the road route than the straight-line distance?
The direct path is about 278.4 miles (448.1 km), while the road route adds roughly 60.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $45.14 one way or $90.28 round trip. Estimated CO2 is about 106.4 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Henderson and Pikeville, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Sunny around Henderson and Patchy Fog then Partly Sunny near Pikeville.
Stop Ideas Near Frankfort
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Frankfort.
Louisville, Kentucky
Cincinnati Museum Center at Union Terminal
Cincinnati, OH
Maysville
Flight Path Map
This map shows the direct air route between Henderson and Pikeville. Straight-line distance: 278.45 mi (448.13 km).
#1 Henderson
City in and county seat of Henderson County, Kentucky, United States
| Population | 27,974 |
| Coordinates | 37.8361500, -87.5900100 |
| Altitude | 124 |
| Country | United States |
#2 Pikeville
City and county seat of Pike County, Kentucky
| Population | 6,432 |
| Coordinates | 37.4792700, -82.5187600 |
| Altitude | 207 |
| Country | United States |
End: Pikeville (-82.51876, 37.47927)
Estimated Travel Time
Distance: 546 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 17m |
| 40 mph (64.37 km/h) | 08h 28m |
| 50 mph (80.47 km/h) | 06h 46m |
| 60 mph (96.56 km/h) | 05h 39m |
| 70 mph (112.65 km/h) | 04h 50m |
| 80 mph (129 km/h) | 04h 13m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $45.14 | $90.28 |
| Mid-grade | $4.25 | $50.91 | $101.82 |
| Premium | $4.65 | $55.71 | $111.42 |
| Diesel | $5.30 | $63.49 | $126.98 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Kentucky · May 07, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.