How far is Oxford, MS from Biloxi, MS?
The driving distance from Oxford, MS to Biloxi, MS is about 179.9 miles (289.5 km), with a travel time of about 03h 01m by car.
- The straight-line flight distance is about 133.8 miles (215.3 km).
- For a round trip, plan for roughly 06h 03m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 01m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Pearl River County, Mississippi, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers
Slight Chance Rain Showers then Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Oxford and Biloxi.
Turn-by-Turn Driving Directions
Step-by-step road directions between Oxford and Biloxi.
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1
Start on Oxford-Meadville Road
3097 ft · 1 min · Oxford-Meadville Road
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2
Turn right onto Busy Corner Road
3.4 mi · 8 min · Busy Corner Road
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3
Turn left onto Van-Norman Road
2.7 mi · 10 min · Van-Norman Road
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4
Turn left
6.9 mi · 10 min
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5
Turn right onto Gillsburg Rd Avenue
1847 ft · 37 sec · Gillsburg Rd Avenue
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6
Continue on Osyka Road
23 mi · 40 min · Osyka Road
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7
Take the ramp slight right
1324 ft · 32 sec
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8
Merge slight left
37.2 mi · 40 min
-
9
Take the exit slight right toward I 12 East: Slidell
1124 ft · 28 sec
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10
Merge slight left onto West Florida Republic Parkway
47.5 mi · 51 min · West Florida Republic Parkway
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11
Continue on West Florida Republic Parkway
1.1 km · 44 sec · West Florida Republic Parkway
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12
Merge slight left onto Stephen E Ambrose Memorial Parkway
51.2 mi · 55 min · Stephen E Ambrose Memorial Parkway
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13
Take the exit slight right toward I 110, MS 15, MS 67: Biloxi, Keesler Air Force Base
605 ft · 15 sec
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14
Keep slight left
2126 ft · 52 sec
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15
Keep slight right to continue on I 110: Biloxi, Keesler Air Force Base
2830 ft · 1 min
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16
Merge slight left
2.7 mi · 4 min
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17
Take the exit slight right toward Division Street
1852 ft · 47 sec
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18
Turn left onto Division Street
3090 ft · 2 min · Division Street
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19
Turn right onto Main Street
2572 ft · 1 min · Main Street
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20
Turn left onto Howard Avenue
28 m · 3 sec · Howard Avenue
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21
Arrive at your destination
0 m · 1 sec · Howard Avenue
Car Route Details
A richer read on the saved driving route between Oxford and Biloxi.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Stephen E Ambrose Memorial Parkway
Merge slight left onto Stephen E Ambrose Memorial Parkway
51.2 mi · 00h 55m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers leaving Oxford and Slight Chance Rain Showers then Mostly Cloudy near Biloxi.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Oxford to Biloxi?
The road trip is about 179.9 miles (289.5 km) and usually takes 03h 01m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Picayune is a useful midpoint, sitting about 89.5 miles from Oxford and 90.3 miles from Biloxi.
How much longer is the road route than the straight-line distance?
The direct path is about 133.8 miles (215.3 km), while the road route adds roughly 46.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:56 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $24.05 one way or $48.09 round trip. Estimated CO2 is about 56.4 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers around Oxford and Slight Chance Rain Showers then Mostly Cloudy near Biloxi.
Stop Ideas Near Picayune
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Picayune.
Picayune
Slidell
Gulfport, MS
Hammond
Flight Path Map
This map shows the direct air route between Oxford and Biloxi. Straight-line distance: 133.75 mi (215.25 km).
#1 Oxford
City in Lafayette County, Mississippi, United States of America
| Population | 28,635 |
| Coordinates | 31.2679500, -90.8981600 |
| Altitude | 128 |
| Country | United States |
#2 Biloxi
The most populous city in Harrison County, Mississippi.
| Population | 46,127 |
| Coordinates | 30.3960300, -88.8853100 |
| Altitude | 6 |
| Country | United States |
End: Howard Avenue (-88.885298, 30.396088)
Estimated Travel Time
Distance: 289 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 59m |
| 40 mph (64.37 km/h) | 04h 29m |
| 50 mph (80.47 km/h) | 03h 35m |
| 60 mph (96.56 km/h) | 02h 59m |
| 70 mph (112.65 km/h) | 02h 34m |
| 80 mph (129 km/h) | 02h 14m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $24.05 | $48.09 |
| Mid-grade | $4.26 | $27.04 | $54.09 |
| Premium | $4.63 | $29.37 | $58.74 |
| Diesel | $5.42 | $34.39 | $68.77 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.