How far is Osseo, WI from La Crosse, WI?
The driving distance from Osseo, WI to La Crosse, WI is about 68.2 miles (109.7 km), with a travel time of about 01h 21m by car.
- The straight-line flight distance is about 53.3 miles (85.7 km).
- For a round trip, plan for roughly 02h 43m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 21m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Civil town in Trempealeau County, Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Partly Sunny
Driving Route Map
The map below follows the saved road route between Osseo and La Crosse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Osseo and La Crosse.
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1
Start on West Street
112 m · 18 sec · West Street
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2
Turn right onto 2nd Street
696 ft · 34 sec · 2nd Street
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3
Turn right onto Harmony Street
646 ft · 12 sec · Harmony Street
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4
Continue on US Highway 53
10.5 mi · 14 min · US Highway 53
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5
Continue on Ekern Street
7.7 mi · 12 min · Ekern Street
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6
At the end of the road, turn left onto Ervin Street
2743 ft · 1 min · Ervin Street
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7
Continue on US Highway 53
24.3 mi · 35 min · US Highway 53
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8
Turn left
17.8 mi · 22 min
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9
Turn straight
3208 ft · 1 min
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10
Turn slight right
744 ft · 18 sec
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11
Turn straight
3.4 mi · 6 min
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12
Continue on Losey Boulevard North
2575 ft · 2 min · Losey Boulevard North
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13
Turn right onto Main Street
1.1 km · 2 min · Main Street
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14
Turn left onto 16th Street South
1.3 km · 2 min · 16th Street South
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15
Turn right onto Johnson Street
1824 ft · 1 min · Johnson Street
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16
At the end of the road, turn right onto West Avenue South
99 m · 11 sec · West Avenue South
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17
Arrive at your destination
0 m · 1 sec · West Avenue South
Car Route Details
A richer read on the saved driving route between Osseo and La Crosse.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
US Highway 53
Continue on US Highway 53
24.3 mi · 00h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Partly Sunny leaving Osseo and Partly Sunny near La Crosse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Osseo to La Crosse?
The road trip is about 68.2 miles (109.7 km) and usually takes 01h 21m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Ettrick is a useful midpoint, sitting about 33.9 miles from Osseo and 34.3 miles from La Crosse.
How much longer is the road route than the straight-line distance?
The direct path is about 53.3 miles (85.7 km), while the road route adds roughly 14.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 3:46 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $9.05 one way or $18.10 round trip. Estimated CO2 is about 21.3 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around Osseo and Partly Sunny near La Crosse.
Stop Ideas Near Ettrick
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Ettrick.
Winona station
La Crosse
Tomah
Eau Claire, WI
Flight Path Map
This map shows the direct air route between Osseo and La Crosse. Straight-line distance: 53.26 mi (85.72 km).
#1 Osseo
City in Trempealeau County, Wisconsin, United States
| Population | 1,671 |
| Coordinates | 44.5721800, -91.2273800 |
| Altitude | 292 |
| Country | United States |
#2 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
End: West Avenue South (-91.239623, 43.801338)
Estimated Travel Time
Distance: 110 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 02h 16m |
| 40 mph (64.37 km/h) | 01h 42m |
| 50 mph (80.47 km/h) | 01h 21m |
| 60 mph (96.56 km/h) | 01h 08m |
| 70 mph (112.65 km/h) | 00h 58m |
| 80 mph (129 km/h) | 00h 51m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $9.05 | $18.10 |
| Mid-grade | $4.25 | $10.21 | $20.41 |
| Premium | $4.65 | $11.17 | $22.34 |
| Diesel | $5.30 | $12.73 | $25.46 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 28, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.