How far is Orlando, FL from Tupelo, MS?
The driving distance from Orlando, FL to Tupelo, MS is about 648.7 miles (1044 km), with a travel time of about 12h 44m by car.
- The straight-line flight distance is about 585.1 miles (941.7 km).
- For a round trip, plan for roughly 25h 28m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 12h 44m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Terrell County, Georgia, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Orlando and Tupelo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Orlando and Tupelo.
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1
Start on the route
35 m · 5 sec
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2
Turn right onto South Orange Avenue
660 ft · 27 sec · South Orange Avenue
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3
Turn straight
73 m · 10 sec
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4
Turn slight right onto Lucerne Circle West
87 m · 13 sec · Lucerne Circle West
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5
Take the ramp slight right toward FL 408 Toll West
1327 ft · 32 sec
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6
Merge slight left onto East-West Expressway
8.2 mi · 10 min · East-West Expressway
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7
Continue on Spessard L. Holland East-West Expressway
1.2 km · 54 sec · Spessard L. Holland East-West Expressway
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8
Keep slight right to continue on Florida's Turnpike North, Ocala
3233 ft · 1 min
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9
Merge slight left onto Florida's Turnpike
42.3 mi · 45 min · Florida's Turnpike
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10
Keep slight left to continue on Florida's Turnpike
1281 ft · 16 sec · Florida's Turnpike
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11
Merge slight left
161.1 mi · 2 hr 53 min
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12
Take the exit slight right toward GA 133: Valdosta, Moultrie
953 ft · 25 sec
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13
Turn left onto Saint Augustine Road
1.9 mi · 3 min · Saint Augustine Road
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14
Continue on Valdosta Highway
19.5 mi · 27 min · Valdosta Highway
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15
Continue on GA 133
9.5 mi · 11 min · GA 133
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16
Merge slight left
5.2 mi · 6 min
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17
Turn right onto Veterans Parkway
1867 ft · 35 sec · Veterans Parkway
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18
Continue on East Bypass
2.2 mi · 3 min · East Bypass
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19
Continue straight
32.3 mi · 39 min
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20
Take the exit slight right toward US 19 North, GA 133 North, GA 300 North: Albany, Atlanta
2958 ft · 46 sec
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21
Merge slight left onto Liberty Expressway
10.7 mi · 13 min · Liberty Expressway
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22
Continue straight
9.5 mi · 12 min
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23
Turn straight onto Albany Highway
5.4 mi · 6 min · Albany Highway
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24
Continue on Forrester Drive Southeast
1.1 mi · 2 min · Forrester Drive Southeast
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25
Continue on Rountree Drive Southwest
2937 ft · 1 min · Rountree Drive Southwest
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26
Continue on Vine Street Northwest
1493 ft · 32 sec · Vine Street Northwest
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27
Continue on Roundtree Drive
1283 ft · 27 sec · Roundtree Drive
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28
Continue on Martin Luther King Jr Drive
2414 ft · 44 sec · Martin Luther King Jr Drive
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29
Continue on Columbus Highway
8 mi · 10 min · Columbus Highway
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30
Continue on South Parrott Street
8.7 mi · 11 min · South Parrott Street
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31
Keep slight left
8.3 mi · 10 min
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32
Continue on Richland Bypass
15.4 mi · 18 min · Richland Bypass
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33
Continue straight
3.3 mi · 4 min
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34
Continue on Martha Berry Highway
16.3 mi · 24 min · Martha Berry Highway
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35
Continue on 4th Street
4 mi · 7 min · 4th Street
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36
Continue straight
2.4 mi · 4 min
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37
Continue straight
20.9 mi · 25 min
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38
Take the exit left toward I-85 South, US 29 South, US 280 West: Auburn, Montgomery
3.1 mi · 3 min
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39
Take the exit slight right toward US 280 West: Opelika, Birmingham
1852 ft · 45 sec
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40
Keep slight right to continue on US 280 West: Opelika, Birmingham
87 m · 7 sec
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41
Merge slight left onto Gateway Drive
1.5 mi · 3 min · Gateway Drive
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42
Continue on Birmingham Highway
3 mi · 4 min · Birmingham Highway
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43
Continue straight
103.8 mi · 2 hr 10 min
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44
Take the exit slight right toward US 31 North, US 280 West: Birmingham
1901 ft · 30 sec
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45
Merge slight left onto Red Mountain Expressway
2.9 mi · 4 min · Red Mountain Expressway
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46
Continue on Carraway Boulevard
1.5 mi · 3 min · Carraway Boulevard
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47
Turn left onto Finley Boulevard
1 km · 1 min · Finley Boulevard
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48
Turn right onto 19th Street North
15 m · 1 sec · 19th Street North
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49
Take the ramp straight toward I 65 North
771 ft · 19 sec
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50
Merge slight left
1.7 mi · 2 min
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51
Take the exit slight right toward I 22 West: Memphis
1.2 mi · 2 min
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52
Continue straight
122.8 mi · 2 hr 12 min
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53
Take the exit slight right toward Auburn Road
1132 ft · 28 sec
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54
Keep slight left
55 m · 6 sec
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55
Turn left
35 m · 3 sec
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56
Turn straight onto Auburn Road
1983 ft · 54 sec · Auburn Road
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57
Continue on North Eason Boulevard
1.5 mi · 2 min · North Eason Boulevard
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58
Turn right onto East Main Street
2.7 mi · 5 min · East Main Street
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59
Turn right onto North Spring Street
70 m · 10 sec · North Spring Street
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60
Arrive at your destination
0 m · 1 sec · North Spring Street
Car Route Details
A richer read on the saved driving route between Orlando and Tupelo.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Merge slight left
161 mi · 02h 53m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Chance Showers And Thunderstorms leaving Orlando and Sunny near Tupelo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Orlando to Tupelo?
The road trip is about 648.7 miles (1044 km) and usually takes 12h 44m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Parrott is a useful midpoint, sitting about 324.5 miles from Orlando and 324.2 miles from Tupelo.
How much longer is the road route than the straight-line distance?
The direct path is about 585.1 miles (941.7 km), while the road route adds roughly 63.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $95.68 one way or $191.36 round trip. Estimated CO2 is about 203.4 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Orlando and Tupelo, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Orlando and Sunny near Tupelo.
Flight Path Map
This map shows the direct air route between Orlando and Tupelo. Straight-line distance: 585.17 mi (941.74 km).
#1 Orlando
The most populous city in Florida and the center of the Orlando metropolitan area.
| Population | 289,457 |
| Coordinates | 28.5383400, -81.3792400 |
| Altitude | 30 |
| Country | United States |
#2 Tupelo
City in and county seat of Lee County, Mississippi, United States
| Population | 38,303 |
| Coordinates | 34.2580700, -88.7046400 |
| Altitude | 85 |
| Country | United States |
End: Tupelo (-88.70464, 34.25807)
Estimated Travel Time
Distance: 1044 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 21h 36m |
| 40 mph (64.37 km/h) | 16h 13m |
| 50 mph (80.47 km/h) | 12h 58m |
| 60 mph (96.56 km/h) | 10h 48m |
| 70 mph (112.65 km/h) | 09h 16m |
| 80 mph (129 km/h) | 08h 05m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.18 | $95.68 | $191.36 |
| Mid-grade | $4.64 | $106.28 | $212.56 |
| Premium | $4.98 | $113.92 | $227.85 |
| Diesel | $5.92 | $135.58 | $271.15 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Oct 09, 2026