How far is New South Memphis, TN from Knoxville, TN?
The driving distance from New South Memphis, TN to Knoxville, TN is about 394.1 miles (634.2 km), with a travel time of about 06h 00m by car.
- The straight-line flight distance is about 350.2 miles (563.6 km).
- For a round trip, plan for roughly 12h 01m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 00m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Cheatham County, Tennessee, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Fog then Partly Sunny
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between New South Memphis and Knoxville.
Turn-by-Turn Driving Directions
Step-by-step road directions between New South Memphis and Knoxville.
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1
Start on South Third Street
1.4 mi · 2 min · South Third Street
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2
Turn right onto South Parkway East
1.4 mi · 3 min · South Parkway East
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3
Continue on South Parkway East
2.7 mi · 4 min · South Parkway East
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4
Continue on South Parkway East
2060 ft · 41 sec · South Parkway East
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5
Continue on East Parkway South
2.3 mi · 4 min · East Parkway South
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6
Turn right onto Sam Cooper Boulevard
6.1 mi · 9 min · Sam Cooper Boulevard
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7
Continue on Isaac Hayes Memorial Highway
196.5 mi · 3 hr 33 min · Isaac Hayes Memorial Highway
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8
Keep slight right to continue on I 40 East, I 65 South: Knoxville, Huntsville
1305 ft · 25 sec
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9
Merge slight left onto Downtown Loop
2.4 mi · 3 min · Downtown Loop
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10
Continue on Downtown Loop
2764 ft · 43 sec · Downtown Loop
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11
Keep slight right to continue on I 40 East, I 24 East: Knoxville, Chattanooga
173.8 mi · 3 hr 10 min
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12
Keep slight left
2.9 mi · 4 min
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13
Take the exit slight right toward Convention Center, East Tennessee History Center, Museum of Art
2116 ft · 28 sec
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14
Keep slight left to continue on Convention Center, East Tennessee History Center, Museum of Art
2403 ft · 56 sec
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15
Continue on Henley Street
1238 ft · 27 sec · Henley Street
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16
Continue on Henley Street
78 m · 12 sec · Henley Street
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17
Arrive at your destination
0 m · 1 sec · Henley Street
Car Route Details
A richer read on the saved driving route between New South Memphis and Knoxville.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Isaac Hayes Memorial Highway
Continue on Isaac Hayes Memorial Highway
197 mi · 03h 33m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Patchy Fog then Partly Sunny leaving New South Memphis and Showers And Thunderstorms Likely near Knoxville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from New South Memphis to Knoxville?
The road trip is about 394.1 miles (634.2 km) and usually takes 06h 00m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Pegram is a useful midpoint, sitting about 195.6 miles from New South Memphis and 198.5 miles from Knoxville.
How much longer is the road route than the straight-line distance?
The direct path is about 350.2 miles (563.6 km), while the road route adds roughly 43.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $52.45 one way or $104.91 round trip. Estimated CO2 is about 123.6 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between New South Memphis and Knoxville, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Patchy Fog then Partly Sunny around New South Memphis and Showers And Thunderstorms Likely near Knoxville.
Stop Ideas Near Pegram
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Pegram.
Nashville, TN
Clarksville, TN
Flight Path Map
This map shows the direct air route between New South Memphis and Knoxville. Straight-line distance: 350.23 mi (563.64 km).
#1 New South Memphis
This area of Memphis, situated in Shelby County at an elevation of 259 feet, is known for its rich musical heritage, particularly its influence on blues and rock and roll.
| Population | 641,608 |
| Coordinates | 35.0867600, -90.0567600 |
| Altitude | 79 |
| Country | United States |
#2 Knoxville
The most populous city in Tennessee.
| Population | 190,223 |
| Coordinates | 35.9606400, -83.9207400 |
| Altitude | 276 |
| Country | United States |
End: US 11 (-83.920795, 35.960617)
Estimated Travel Time
Distance: 634 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 07m |
| 40 mph (64.37 km/h) | 09h 51m |
| 50 mph (80.47 km/h) | 07h 52m |
| 60 mph (96.56 km/h) | 06h 34m |
| 70 mph (112.65 km/h) | 05h 37m |
| 80 mph (129 km/h) | 04h 54m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $52.45 | $104.91 |
| Mid-grade | $4.25 | $59.16 | $118.32 |
| Premium | $4.65 | $64.74 | $129.47 |
| Diesel | $5.30 | $73.78 | $147.56 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · May 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.