How far is Neosho, MO from Chesterfield, MO?
The driving distance from Neosho, MO to Chesterfield, MO is about 275 miles (442.6 km), with a travel time of about 04h 24m by car.
- The straight-line flight distance is about 241.3 miles (388.3 km).
- For a round trip, plan for roughly 08h 48m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 24m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy then Slight Chance Showers And Thunderstorms
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Neosho and Chesterfield.
Turn-by-Turn Driving Directions
Step-by-step road directions between Neosho and Chesterfield.
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1
Start on East Main Street
66 m · 15 sec · East Main Street
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2
Turn left onto South Washington Street
1506 ft · 53 sec · South Washington Street
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3
At the end of the road, turn left onto East Coler Street
1106 ft · 26 sec · East Coler Street
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4
Turn right onto North College Street
1.3 mi · 2 min · North College Street
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5
Continue on Elwood Junction Road
3.1 mi · 4 min · Elwood Junction Road
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6
Turn left
1382 ft · 51 sec
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7
Turn straight
11.7 mi · 17 min
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8
Take the ramp slight right toward I 44 East: Springfield
2007 ft · 43 sec
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9
Merge slight left onto Congressman Gene Taylor Highway
234.4 mi · 4 hr 13 min · Congressman Gene Taylor Highway
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10
Take the exit slight right toward I 44 Business, MO 100 East: Gray Summit
970 ft · 28 sec
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11
Turn left onto Manchester Road
16.8 mi · 24 min · Manchester Road
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12
Turn left onto Clarkson Road
3.6 mi · 7 min · Clarkson Road
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13
Turn left onto Baxter Road
1.6 mi · 3 min · Baxter Road
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14
Turn right onto Wild Horse Creek Road
598 ft · 23 sec · Wild Horse Creek Road
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15
Turn left onto Santa Maria Drive
1514 ft · 1 min · Santa Maria Drive
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16
Arrive at your destination
0 m · 1 sec · Santa Maria Drive
Car Route Details
A richer read on the saved driving route between Neosho and Chesterfield.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Congressman Gene Taylor Highway
Merge slight left onto Congressman Gene Taylor Highway
234 mi · 04h 13m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Cloudy then Slight Chance Showers And Thunderstorms leaving Neosho and Mostly Sunny near Chesterfield.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Neosho to Chesterfield?
The road trip is about 275 miles (442.6 km) and usually takes 04h 24m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Stoutland is a useful midpoint, sitting about 137.1 miles from Neosho and 138 miles from Chesterfield.
How much longer is the road route than the straight-line distance?
The direct path is about 241.3 miles (388.3 km), while the road route adds roughly 33.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:12 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $36.62 one way or $73.23 round trip. Estimated CO2 is about 86.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Cloudy then Slight Chance Showers And Thunderstorms around Neosho and Mostly Sunny near Chesterfield.
Stop Ideas Near Stoutland
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Stoutland.
Jefferson City
Sedalia
Flight Path Map
This map shows the direct air route between Neosho and Chesterfield. Straight-line distance: 241.3 mi (388.33 km).
#1 Neosho
City in Newton County, Missouri, United States
| Population | 12,116 |
| Coordinates | 36.8689600, -94.3680000 |
| Altitude | 316 |
| Country | United States |
#2 Chesterfield
A city in St.
| Population | 47,570 |
| Coordinates | 38.6631100, -90.5770700 |
| Altitude | 144 |
| Country | United States |
End: Santa Maria Drive (-90.576914, 38.663102)
Estimated Travel Time
Distance: 443 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 09m |
| 40 mph (64.37 km/h) | 06h 52m |
| 50 mph (80.47 km/h) | 05h 30m |
| 60 mph (96.56 km/h) | 04h 35m |
| 70 mph (112.65 km/h) | 03h 55m |
| 80 mph (129 km/h) | 03h 25m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $36.62 | $73.23 |
| Mid-grade | $4.25 | $41.30 | $82.59 |
| Premium | $4.65 | $45.19 | $90.38 |
| Diesel | $5.30 | $51.50 | $103.00 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.