How far is Neosho, MO from Saint Charles, MO?
The driving distance from Neosho, MO to Saint Charles, MO is about 294.7 miles (474.2 km), with a travel time of about 04h 36m by car.
- The straight-line flight distance is about 250 miles (402.3 km).
- For a round trip, plan for roughly 09h 12m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 36m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri parts of witch are in Camden, Laclede, and Pulaski Counties
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Neosho and Saint Charles.
Turn-by-Turn Driving Directions
Step-by-step road directions between Neosho and Saint Charles.
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1
Start on East Main Street
66 m · 15 sec · East Main Street
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2
Turn left onto South Washington Street
1506 ft · 53 sec · South Washington Street
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3
At the end of the road, turn left onto East Coler Street
1106 ft · 26 sec · East Coler Street
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4
Turn right onto North College Street
1.3 mi · 2 min · North College Street
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5
Continue on Elwood Junction Road
3.1 mi · 4 min · Elwood Junction Road
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6
Turn left
1382 ft · 51 sec
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7
Turn straight
11.7 mi · 17 min
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8
Take the ramp slight right toward I 44 East: Springfield
2007 ft · 43 sec
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9
Merge slight left onto Congressman Gene Taylor Highway
257.2 mi · 4 hr 39 min · Congressman Gene Taylor Highway
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10
Take the exit slight right toward I 270: Chicago, Memphis
871 ft · 19 sec
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11
Keep slight left to continue on I 270 North: Chicago
551 ft · 12 sec
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12
Continue on I 270 North: Chicago
2638 ft · 53 sec
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13
Merge slight left
12.6 mi · 16 min
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14
Take the exit slight right toward I 70: Kansas City, Saint Louis, Saint Louis Lambert International Airport
1 mi · 1 min
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15
Keep slight left to continue on I 70 West: Kansas City
645 ft · 11 sec
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16
Continue on I 70 West: Kansas City
1 km · 57 sec
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17
Merge slight left
2.7 mi · 3 min
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18
Take the exit slight right toward I 70 Business: Fifth Street
841 ft · 18 sec
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19
Keep slight right to continue on I 70 Business: Fifth Street North, Bass Pro Drive, Ameristar Boulevard
71 m · 5 sec
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20
Turn slight right onto South Fifth Street
1.6 km · 2 min · South Fifth Street
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21
Turn right onto Jefferson Street
1093 ft · 44 sec · Jefferson Street
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22
Turn left onto North Second Street
949 ft · 34 sec · North Second Street
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23
Arrive at your destination
0 m · 1 sec · North Second Street
Car Route Details
A richer read on the saved driving route between Neosho and Saint Charles.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Congressman Gene Taylor Highway
Merge slight left onto Congressman Gene Taylor Highway
257 mi · 04h 39m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Neosho and Showers And Thunderstorms near Saint Charles.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Neosho to Saint Charles?
The road trip is about 294.7 miles (474.2 km) and usually takes 04h 36m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Richland is a useful midpoint, sitting about 146.8 miles from Neosho and 147.8 miles from Saint Charles.
How much longer is the road route than the straight-line distance?
The direct path is about 250 miles (402.3 km), while the road route adds roughly 44.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 7:48 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $39.22 one way or $78.44 round trip. Estimated CO2 is about 92.4 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Neosho and Showers And Thunderstorms near Saint Charles.
Stop Ideas Near Richland
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Richland.
Jefferson City
Sedalia
Flight Path Map
This map shows the direct air route between Neosho and Saint Charles. Straight-line distance: 249.97 mi (402.28 km).
#1 Neosho
City in Newton County, Missouri, United States
| Population | 12,116 |
| Coordinates | 36.8689600, -94.3680000 |
| Altitude | 316 |
| Country | United States |
#2 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
End: North Second Street (-90.481269, 38.783952)
Estimated Travel Time
Distance: 474 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 49m |
| 40 mph (64.37 km/h) | 07h 21m |
| 50 mph (80.47 km/h) | 05h 53m |
| 60 mph (96.56 km/h) | 04h 54m |
| 70 mph (112.65 km/h) | 04h 12m |
| 80 mph (129 km/h) | 03h 40m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $39.22 | $78.44 |
| Mid-grade | $4.25 | $44.23 | $88.46 |
| Premium | $4.65 | $48.40 | $96.80 |
| Diesel | $5.30 | $55.16 | $110.32 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 05, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.