How far is Myrtle Grove, FL from Cape Coral, FL?
The driving distance from Myrtle Grove, FL to Cape Coral, FL is about 606 miles (975.3 km), with a travel time of about 09h 09m by car.
- The straight-line flight distance is about 420.5 miles (676.7 km).
- For a round trip, plan for roughly 18h 18m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 09h 09m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat of Columbia County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Partly Sunny
Driving Route Map
The map below follows the saved road route between Myrtle Grove and Cape Coral.
Turn-by-Turn Driving Directions
Step-by-step road directions between Myrtle Grove and Cape Coral.
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1
Start on the route
37 m · 11 sec
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2
At the end of the road, turn right
16 m · 9 sec
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3
Turn left onto Lillian Highway
1.6 km · 2 min · Lillian Highway
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4
Turn left onto North 57th Avenue
2274 ft · 1 min · North 57th Avenue
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5
At the end of the road, turn right onto West Fairfield Drive
3.8 mi · 7 min · West Fairfield Drive
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6
Keep slight left to continue on West Fairfield Drive
1.4 km · 2 min · West Fairfield Drive
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7
Turn right onto North Davis Highway
597 ft · 12 sec · North Davis Highway
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8
Take the ramp right toward I 110 North
993 ft · 24 sec
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9
Merge slight left onto Reubin O'Donovan Askew Parkway
3.3 mi · 4 min · Reubin O'Donovan Askew Parkway
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10
Keep slight right to continue on I 10 East, FL 291: Tallahassee, Davis Highway
1328 ft · 28 sec
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11
Keep slight left to continue on I 10 East: Tallahassee
1.1 km · 1 min
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12
Merge slight left
282.9 mi · 5 hr 3 min
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13
Take the exit slight right toward I-75 South: Tampa
1959 ft · 37 sec
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14
Merge slight left
160.5 mi · 2 hr 52 min
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15
Keep slight left to continue on South I 75: Naples
74.3 mi · 1 hr 20 min
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16
Keep slight left
42.2 mi · 45 min
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17
Take the exit slight right toward CR 762: North Fort Myers, Cape Coral
1532 ft · 37 sec
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18
Keep slight right to continue on CR 762 West, to US 41
859 ft · 21 sec
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19
Turn straight onto Tuckers Grade
1.4 km · 2 min · Tuckers Grade
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20
Turn left onto Tamiami Trail
10.4 mi · 13 min · Tamiami Trail
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21
Turn right onto Del Prado Boulevard North
6.5 mi · 11 min · Del Prado Boulevard North
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22
Continue on Del Prado Boulevard South
6.2 mi · 13 min · Del Prado Boulevard South
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23
Turn right onto Cape Coral Parkway East
1669 ft · 41 sec · Cape Coral Parkway East
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24
Turn right
61 m · 15 sec
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25
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Myrtle Grove and Cape Coral.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 10 East
Merge slight left
283 mi · 05h 03m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving Myrtle Grove and Partly Sunny near Cape Coral.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Myrtle Grove to Cape Coral?
The road trip is about 606 miles (975.3 km) and usually takes 09h 09m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Lake City is a useful midpoint, sitting about 297.9 miles from Myrtle Grove and 308.1 miles from Cape Coral.
How much longer is the road route than the straight-line distance?
The direct path is about 420.5 miles (676.7 km), while the road route adds roughly 185.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $88.68 one way or $177.37 round trip. Estimated CO2 is about 190 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Myrtle Grove and Cape Coral, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Sunny around Myrtle Grove and Partly Sunny near Cape Coral.
Stop Ideas Near Lake City
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lake City.
Waldo, Florida
Gainesville, Florida
Jacksonville
Palatka
Flight Path Map
This map shows the direct air route between Myrtle Grove and Cape Coral. Straight-line distance: 420.51 mi (676.75 km).
#1 Myrtle Grove
Census-designated place in Escambia County, Florida
| Population | 15,870 |
| Coordinates | 30.4210300, -87.3074700 |
| Altitude | 14 |
| Country | United States |
#2 Cape Coral
The second most populous city in Lee County, Florida.
| Population | 200,972 |
| Coordinates | 26.5628500, -81.9495300 |
| Altitude | 1 |
| Country | United States |
End: (-81.94953, 26.562855)
Estimated Travel Time
Distance: 975 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 20h 11m |
| 40 mph (64.37 km/h) | 15h 09m |
| 50 mph (80.47 km/h) | 12h 07m |
| 60 mph (96.56 km/h) | 10h 06m |
| 70 mph (112.65 km/h) | 08h 39m |
| 80 mph (129 km/h) | 07h 33m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $88.68 | $177.37 |
| Mid-grade | $4.60 | $98.26 | $196.52 |
| Premium | $4.90 | $104.68 | $209.35 |
| Diesel | $4.35 | $93.00 | $186.01 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.