How far is Myrtle Beach, SC from Cayce, SC?
The driving distance from Myrtle Beach, SC to Cayce, SC is about 144.7 miles (232.9 km), with a travel time of about 03h 11m by car.
- The straight-line flight distance is about 127 miles (204.4 km).
- For a round trip, plan for roughly 06h 22m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 11m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Clarendon County, South Carolina, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Clear
Driving Route Map
The map below follows the saved road route between Myrtle Beach and Cayce.
Turn-by-Turn Driving Directions
Step-by-step road directions between Myrtle Beach and Cayce.
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1
Start on the route
21 m · 10 sec
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2
Turn left
49 m · 14 sec
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3
At the end of the road, turn right onto North Kings Highway
609 ft · 20 sec · North Kings Highway
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4
Turn left onto 6th Avenue North
149 m · 22 sec · 6th Avenue North
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5
Continue on 6th Avenue North
889 ft · 46 sec · 6th Avenue North
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6
At the end of the road, turn right onto Alder Street
47 m · 7 sec · Alder Street
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7
Turn left
10.5 mi · 16 min
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8
Continue on Highway 501 East
2 mi · 3 min · Highway 501 East
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9
Continue on Church Street
1.5 mi · 2 min · Church Street
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10
Turn left onto Wright Boulevard
1.1 mi · 2 min · Wright Boulevard
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11
Continue on Highway 378
22.9 mi · 32 min · Highway 378
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12
Continue on East Myrtle Beach Highway
36.1 mi · 43 min · East Myrtle Beach Highway
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13
Continue on Main Street
2637 ft · 1 min · Main Street
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14
Turn slight right onto Clarence Coker Highway
3.5 mi · 5 min · Clarence Coker Highway
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15
Continue on Myrtle Beach Highway
13 mi · 17 min · Myrtle Beach Highway
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16
Keep slight right to continue on Robert E Graham Freeway
6.4 mi · 7 min · Robert E Graham Freeway
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17
Merge slight left onto Broad Street
34.7 mi · 43 min · Broad Street
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18
Take the exit slight left toward I 77 South: Charleston, Spartanburg
2651 ft · 1 min
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19
Merge slight left onto William Earle Berne Beltway
5 mi · 5 min · William Earle Berne Beltway
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20
Continue on Veterans Memorial Freeway
2.4 mi · 3 min · Veterans Memorial Freeway
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21
Take the exit slight right toward US 21, US 176, US 321: Gaston, Swansea
1.1 mi · 2 min
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22
Turn right onto Charleston Highway
2.7 mi · 3 min · Charleston Highway
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23
Turn right onto Glenn Street
1515 ft · 58 sec · Glenn Street
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24
Turn left onto Middleton Street
50 m · 6 sec · Middleton Street
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25
Arrive at your destination
0 m · 1 sec · Middleton Street
Car Route Details
A richer read on the saved driving route between Myrtle Beach and Cayce.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
East Myrtle Beach Highway
Continue on East Myrtle Beach Highway
36.1 mi · 00h 43m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Clear leaving Myrtle Beach and Sunny near Cayce.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Myrtle Beach to Cayce?
The road trip is about 144.7 miles (232.9 km) and usually takes 03h 11m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Turbeville is a useful midpoint, sitting about 72.3 miles from Myrtle Beach and 72.5 miles from Cayce.
How much longer is the road route than the straight-line distance?
The direct path is about 127 miles (204.4 km), while the road route adds roughly 17.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 10:38 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $20.24 one way or $40.48 round trip. Estimated CO2 is about 45.4 kg one way.
What should you check before leaving?
Before you leave, expect Clear around Myrtle Beach and Sunny near Cayce.
Stop Ideas Near Turbeville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Turbeville.
Kingstree
Florence
Camden
Dillon
Flight Path Map
This map shows the direct air route between Myrtle Beach and Cayce. Straight-line distance: 126.99 mi (204.37 km).
#1 Myrtle Beach
Coastal city in South Carolina, United States
| Population | 35,555 |
| Coordinates | 33.6890600, -78.8866900 |
| Altitude | 8 |
| Country | United States |
#2 Cayce
City in Lexington and Richland counties in South Carolina, United States
| Population | 13,994 |
| Coordinates | 33.9657100, -81.0739800 |
| Altitude | 73 |
| Country | United States |
End: Cayce (-81.07398, 33.96571)
Estimated Travel Time
Distance: 233 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 49m |
| 40 mph (64.37 km/h) | 03h 37m |
| 50 mph (80.47 km/h) | 02h 53m |
| 60 mph (96.56 km/h) | 02h 24m |
| 70 mph (112.65 km/h) | 02h 04m |
| 80 mph (129 km/h) | 01h 48m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $20.24 | $40.48 |
| Mid-grade | $4.43 | $22.63 | $45.26 |
| Premium | $4.78 | $24.42 | $48.83 |
| Diesel | $5.62 | $28.74 | $57.48 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.