How far is Muscatine, IA from Sioux City, IA?
The driving distance from Muscatine, IA to Sioux City, IA is about 331.3 miles (533.2 km), with a travel time of about 05h 11m by car.
- The straight-line flight distance is about 285 miles (458.7 km).
- For a round trip, plan for roughly 10h 22m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 11m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Dallas County, Iowa, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers then Slight Chance Showers And Thunderstorms
Chance Rain Showers then Mostly Sunny
Driving Route Map
The map below follows the saved road route between Muscatine and Sioux City.
Turn-by-Turn Driving Directions
Step-by-step road directions between Muscatine and Sioux City.
-
1
Start on Walnut Street
48 m · 11 sec · Walnut Street
-
2
Turn left onto East 3rd Street
110 m · 18 sec · East 3rd Street
-
3
Turn right onto Mulberry Avenue
101 m · 10 sec · Mulberry Avenue
-
4
Enter the roundabout and take exit 3 toward East 2nd Street
59 m · 4 sec · East 2nd Street
-
5
Exit the roundabout onto East 2nd Street
1 km · 1 min · East 2nd Street
-
6
Continue on Park Avenue
2 mi · 4 min · Park Avenue
-
7
Continue on State Highway 38
7.6 mi · 10 min · State Highway 38
-
8
Continue straight
4.9 mi · 7 min
-
9
Take the ramp straight
1468 ft · 36 sec
-
10
Merge slight left
146.8 mi · 2 hr 40 min
-
11
Keep slight right to continue on I 80 West: Omaha
95.5 mi · 1 hr 43 min
-
12
Keep slight right to continue on I 880 West: North Omaha, Sioux City
16.7 mi · 18 min
-
13
Keep slight right to continue on I 29 North: Sioux City
2271 ft · 39 sec
-
14
Merge slight left
75.3 mi · 1 hr 21 min
-
15
Take the exit slight right toward Floyd Boulevard, Virginia Street
1582 ft · 43 sec
-
16
Turn right onto South Floyd Boulevard
3174 ft · 1 min · South Floyd Boulevard
-
17
Turn left onto 5th Street
121 m · 15 sec · 5th Street
-
18
Turn right onto Iowa Street
105 m · 7 sec · Iowa Street
-
19
Keep slight left to continue on 6th Street
130 m · 17 sec · 6th Street
-
20
Turn right onto Court Street
1199 ft · 39 sec · Court Street
-
21
Turn left onto 9th Street
990 ft · 46 sec · 9th Street
-
22
Turn right
35 m · 9 sec
-
23
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Muscatine and Sioux City.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
State Highway 38
Merge slight left
147 mi · 02h 40m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers then Slight Chance Showers And Thunderstorms leaving Muscatine and Chance Rain Showers then Mostly Sunny near Sioux City.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Muscatine to Sioux City?
The road trip is about 331.3 miles (533.2 km) and usually takes 05h 11m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
De Soto is a useful midpoint, sitting about 175.6 miles from Muscatine and 155.7 miles from Sioux City.
How much longer is the road route than the straight-line distance?
The direct path is about 285 miles (458.7 km), while the road route adds roughly 46.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:38 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $44.08 one way or $88.17 round trip. Estimated CO2 is about 103.9 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers then Slight Chance Showers And Thunderstorms around Muscatine and Chance Rain Showers then Mostly Sunny near Sioux City.
Stop Ideas Near De Soto
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to De Soto.
Osceola
Creston
Flight Path Map
This map shows the direct air route between Muscatine and Sioux City. Straight-line distance: 285.03 mi (458.71 km).
#1 Muscatine
City in and county seat of Muscatine County, Iowa
| Population | 23,523 |
| Coordinates | 41.4244700, -91.0432100 |
| Altitude | 177 |
| Country | United States |
#2 Sioux City
The second most populous city in Iowa.
| Population | 82,651 |
| Coordinates | 42.4999900, -96.4003100 |
| Altitude | 366 |
| Country | United States |
End: (-96.400135, 42.499991)
Estimated Travel Time
Distance: 533 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 02m |
| 40 mph (64.37 km/h) | 08h 17m |
| 50 mph (80.47 km/h) | 06h 37m |
| 60 mph (96.56 km/h) | 05h 31m |
| 70 mph (112.65 km/h) | 04h 44m |
| 80 mph (129 km/h) | 04h 08m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $44.08 | $88.17 |
| Mid-grade | $4.25 | $49.72 | $99.44 |
| Premium | $4.65 | $54.41 | $108.81 |
| Diesel | $5.30 | $62.00 | $124.01 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Iowa · May 12, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.