How far is Murphy, NC from Winston-Salem, NC?
The driving distance from Murphy, NC to Winston-Salem, NC is about 253.5 miles (407.9 km), with a travel time of about 04h 15m by car.
- The straight-line flight distance is about 224.1 miles (360.7 km).
- For a round trip, plan for roughly 08h 30m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 15m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Murphy and Winston-Salem.
Turn-by-Turn Driving Directions
Step-by-step road directions between Murphy and Winston-Salem.
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1
Start on Hiwassee Street
36 m · 6 sec · Hiwassee Street
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2
Turn right
19 m · 3 sec
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3
Turn right onto Peachtree Street
2943 ft · 2 min · Peachtree Street
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4
Turn left onto US 19
24.1 mi · 33 min · US 19
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5
Continue on US Highway 19
9.9 mi · 13 min · US Highway 19
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6
Turn left
52.5 mi · 1 hr 5 min
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7
Keep slight right to continue on I 40 East: Asheville
160.4 mi · 3 hr 5 min
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8
Take the exit slight left toward US 421 South: Salem Parkway
2800 ft · 37 sec
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9
Merge slight left onto Salem Parkway
4.7 mi · 6 min · Salem Parkway
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10
Take the exit slight right toward Marshall Street, TO Cherry Street
582 ft · 14 sec
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11
Continue on High Street Southwest
140 m · 15 sec · High Street Southwest
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12
Turn left onto Cherry Street South
1223 ft · 27 sec · Cherry Street South
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13
Turn right onto West 2nd Street
901 ft · 25 sec · West 2nd Street
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14
Turn left onto North Main Street
1314 ft · 26 sec · North Main Street
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15
Arrive at your destination
0 m · 1 sec · North Main Street
Car Route Details
A richer read on the saved driving route between Murphy and Winston-Salem.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 40 East
Keep slight right to continue on I 40 East: Asheville
160 mi · 03h 05m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Murphy and Mostly Sunny near Winston-Salem.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Murphy to Winston-Salem?
The road trip is about 253.5 miles (407.9 km) and usually takes 04h 15m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Montreat is a useful midpoint, sitting about 126.6 miles from Murphy and 126.9 miles from Winston-Salem.
How much longer is the road route than the straight-line distance?
The direct path is about 224.1 miles (360.7 km), while the road route adds roughly 29.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:30 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.41 one way or $70.82 round trip. Estimated CO2 is about 79.4 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Murphy and Mostly Sunny near Winston-Salem.
Stop Ideas Near Montreat
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Montreat.
Spartanburg
Greenville
Gastonia
Clemson
Flight Path Map
This map shows the direct air route between Murphy and Winston-Salem. Straight-line distance: 224.13 mi (360.71 km).
#1 Murphy
Town in Cherokee County, North Carolina
| Population | 1,666 |
| Coordinates | 35.0875800, -84.0346300 |
| Altitude | 486 |
| Country | United States |
#2 Winston-Salem
The fifth most populous city in North Carolina.
| Population | 248,112 |
| Coordinates | 36.0998600, -80.2442200 |
| Altitude | 293 |
| Country | United States |
End: North Main Street (-80.244255, 36.099856)
Estimated Travel Time
Distance: 408 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 26m |
| 40 mph (64.37 km/h) | 06h 20m |
| 50 mph (80.47 km/h) | 05h 04m |
| 60 mph (96.56 km/h) | 04h 13m |
| 70 mph (112.65 km/h) | 03h 37m |
| 80 mph (129 km/h) | 03h 09m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $35.41 | $70.82 |
| Mid-grade | $4.43 | $39.60 | $79.19 |
| Premium | $4.78 | $42.72 | $85.43 |
| Diesel | $5.62 | $50.28 | $100.56 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in North Carolina · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.