How far is Murphy, NC from Durham, NC?
The driving distance from Murphy, NC to Durham, NC is about 332.8 miles (535.6 km), with a travel time of about 05h 28m by car.
- The straight-line flight distance is about 295.4 miles (475.4 km).
- For a round trip, plan for roughly 10h 57m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 28m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Burke County, North Carolina, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Murphy and Durham.
Turn-by-Turn Driving Directions
Step-by-step road directions between Murphy and Durham.
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1
Start on Hiwassee Street
36 m · 6 sec · Hiwassee Street
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2
Turn right
19 m · 3 sec
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3
Turn right onto Peachtree Street
2943 ft · 2 min · Peachtree Street
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4
Turn left onto US 19
24.1 mi · 33 min · US 19
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5
Continue on US Highway 19
9.9 mi · 13 min · US Highway 19
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6
Turn left
52.5 mi · 1 hr 5 min
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7
Keep slight right to continue on I 40 East: Asheville
184.2 mi · 3 hr 33 min
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8
Keep slight right to continue on I 40 East: Greensboro, Martinsville
7.8 mi · 10 min
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9
Merge slight right
1.8 mi · 2 min
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10
Keep slight left
36.8 mi · 43 min
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11
Keep slight left to continue on I 85 North: Durham
9.4 mi · 11 min
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12
Keep slight right to continue on Durham Freeway
5.2 mi · 7 min · Durham Freeway
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13
Take the exit slight right toward Mangum Street, Roxboro Street
156 m · 13 sec
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14
Continue on Morehead Avenue
854 ft · 29 sec · Morehead Avenue
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15
Turn left onto South Roxboro Street
1963 ft · 59 sec · South Roxboro Street
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16
Turn left onto East Main Street
30 m · 2 sec · East Main Street
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17
Arrive at your destination
0 m · 1 sec · East Main Street
Car Route Details
A richer read on the saved driving route between Murphy and Durham.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 40 East
Keep slight right to continue on I 40 East: Asheville
184 mi · 03h 33m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Murphy and Mostly Sunny near Durham.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Murphy to Durham?
The road trip is about 332.8 miles (535.6 km) and usually takes 05h 28m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Drexel is a useful midpoint, sitting about 166.2 miles from Murphy and 166.7 miles from Durham.
How much longer is the road route than the straight-line distance?
The direct path is about 295.4 miles (475.4 km), while the road route adds roughly 37.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:02 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.54 one way or $93.08 round trip. Estimated CO2 is about 104.4 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Murphy and Mostly Sunny near Durham.
Stop Ideas Near Drexel
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Casar Park, Town Hall, & Veterans Memorial
City of Lenoir
Longview Town Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Drexel.
Gastonia
Charlotte
Kannapolis
Spartanburg
Flight Path Map
This map shows the direct air route between Murphy and Durham. Straight-line distance: 295.43 mi (475.45 km).
#1 Murphy
Town in Cherokee County, North Carolina
| Population | 1,666 |
| Coordinates | 35.0875800, -84.0346300 |
| Altitude | 486 |
| Country | United States |
#2 Durham
The third most populous city in North Carolina and the center of the Durham metropolitan area.
| Population | 285,897 |
| Coordinates | 35.9940300, -78.8986200 |
| Altitude | 123 |
| Country | United States |
End: (-78.898591, 35.994064)
Estimated Travel Time
Distance: 536 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 05m |
| 40 mph (64.37 km/h) | 08h 19m |
| 50 mph (80.47 km/h) | 06h 39m |
| 60 mph (96.56 km/h) | 05h 32m |
| 70 mph (112.65 km/h) | 04h 45m |
| 80 mph (129 km/h) | 04h 09m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $46.54 | $93.08 |
| Mid-grade | $4.43 | $52.04 | $104.08 |
| Premium | $4.78 | $56.14 | $112.28 |
| Diesel | $5.62 | $66.08 | $132.16 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in North Carolina · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.