How far is Monroe City, MO from St. Louis, MO?
The driving distance from Monroe City, MO to St. Louis, MO is about 129.1 miles (207.8 km), with a travel time of about 02h 11m by car.
- The straight-line flight distance is about 108.7 miles (174.9 km).
- For a round trip, plan for roughly 04h 23m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 11m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Lincoln County, Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny then Chance Showers And Thunderstorms
Mostly Sunny then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Monroe City and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between Monroe City and St. Louis.
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1
Start on North Main Street
1353 ft · 24 sec · North Main Street
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2
Turn right onto 5th Street
1.1 mi · 2 min · 5th Street
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3
Turn left
1930 ft · 34 sec
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4
Take the ramp right toward US 24 East, US 36 East, MO 110 East: Hannibal
1671 ft · 22 sec
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5
Merge slight left onto Chicago-Kansas City Expressway
10.8 mi · 12 min · Chicago-Kansas City Expressway
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6
Continue on V.F.W. Memorial Highway
5.8 mi · 7 min · V.F.W. Memorial Highway
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7
Take the exit slight right toward Veterans Road
1167 ft · 30 sec
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8
Turn right onto Veterans Road
2.1 mi · 4 min · Veterans Road
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9
At the end of the road, turn left onto County Road 422
85 m · 7 sec · County Road 422
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10
Continue on Paris Gravel Road
2539 ft · 1 min · Paris Gravel Road
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11
Take the ramp right
37 m · 3 sec
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12
Merge slight left onto Avenue of the Saints
101.3 mi · 2 hr 1 min · Avenue of the Saints
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13
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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14
Continue on Jack Buck Memorial Highway
5.8 mi · 7 min · Jack Buck Memorial Highway
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15
Take the exit slight right toward 14th Street
1115 ft · 34 sec
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16
Turn left onto South 14th Street
1715 ft · 42 sec · South 14th Street
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17
Turn right onto Market Street
956 ft · 25 sec · Market Street
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18
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between Monroe City and St. Louis.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Avenue of the Saints
Merge slight left onto Avenue of the Saints
101 mi · 02h 01m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny then Chance Showers And Thunderstorms leaving Monroe City and Mostly Sunny then Chance Showers And Thunderstorms near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Monroe City to St. Louis?
The road trip is about 129.1 miles (207.8 km) and usually takes 02h 11m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Whiteside is a useful midpoint, sitting about 67.5 miles from Monroe City and 61.6 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 108.7 miles (174.9 km), while the road route adds roughly 20.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 2:06 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $17.20 one way or $34.39 round trip. Estimated CO2 is about 40.5 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny then Chance Showers And Thunderstorms around Monroe City and Mostly Sunny then Chance Showers And Thunderstorms near St. Louis.
Stop Ideas Near Whiteside
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Whiteside.
Hermann
Washington
Alton
Kirkwood
Flight Path Map
This map shows the direct air route between Monroe City and St. Louis. Straight-line distance: 108.67 mi (174.89 km).
#1 Monroe City
City in Monroe County, Missouri, United States
| Population | 2,438 |
| Coordinates | 39.6536500, -91.7346100 |
| Altitude | 227 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 208 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 18m |
| 40 mph (64.37 km/h) | 03h 13m |
| 50 mph (80.47 km/h) | 02h 34m |
| 60 mph (96.56 km/h) | 02h 09m |
| 70 mph (112.65 km/h) | 01h 50m |
| 80 mph (129 km/h) | 01h 36m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $17.20 | $34.39 |
| Mid-grade | $4.25 | $19.39 | $38.79 |
| Premium | $4.65 | $21.22 | $42.44 |
| Diesel | $5.30 | $24.19 | $48.37 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 17, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.