How far is Mishicot, WI from La Crosse, WI?
The driving distance from Mishicot, WI to La Crosse, WI is about 220.2 miles (354.4 km), with a travel time of about 04h 04m by car.
- The straight-line flight distance is about 181.3 miles (291.8 km).
- For a round trip, plan for roughly 08h 08m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 04m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Marquette County, Wisconsin, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Mostly Sunny then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Mishicot and La Crosse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mishicot and La Crosse.
-
1
Start on Rockway Street
4 m · 1 sec · Rockway Street
-
2
Turn right onto East Main Street
1246 ft · 21 sec · East Main Street
-
3
Continue on State Highway 147
3244 ft · 55 sec · State Highway 147
-
4
Continue on West Main Street
6.8 mi · 10 min · West Main Street
-
5
Take the ramp right
1943 ft · 48 sec
-
6
Merge slight left
15.5 mi · 17 min
-
7
Take the exit slight right toward WI 172 West: Austin Straubel Airport
1.1 mi · 2 min
-
8
Continue straight
5.4 mi · 7 min
-
9
Take the exit slight right toward I 41 South: Appleton
1.1 km · 1 min
-
10
Merge slight left
49.1 mi · 53 min
-
11
Take the exit slight right toward WI 44, WI 91
1444 ft · 35 sec
-
12
Keep slight right
56 m · 5 sec
-
13
Turn right onto Ripon Rd
1.3 km · 1 min · Ripon Rd
-
14
Continue on State Highway 44
14.8 mi · 22 min · State Highway 44
-
15
Continue on East Oshkosh Street
1.5 mi · 4 min · East Oshkosh Street
-
16
Turn right onto West Fond du Lac Street
1.4 mi · 3 min · West Fond du Lac Street
-
17
Continue on State Highway 23 & 49
3.7 mi · 5 min · State Highway 23 & 49
-
18
Turn straight onto State Highway 23
9.2 mi · 13 min · State Highway 23
-
19
Continue on South Fulton Street
1.2 km · 1 min · South Fulton Street
-
20
Turn left onto West Main Street
1.3 km · 1 min · West Main Street
-
21
Turn left
46 m · 3 sec
-
22
Continue on South 2nd Street
2515 ft · 43 sec · South 2nd Street
-
23
Continue on State Highway 23
9.9 mi · 15 min · State Highway 23
-
24
Continue on East Montello Street
3142 ft · 57 sec · East Montello Street
-
25
Continue on West Montello Street
635 ft · 11 sec · West Montello Street
-
26
Turn slight right onto Underwood Avenue
1.8 mi · 3 min · Underwood Avenue
-
27
Continue on State Highway 23
6.1 mi · 8 min · State Highway 23
-
28
Continue on State Highway 82
3.5 mi · 5 min · State Highway 82
-
29
Continue on East Ormsby Street
1.1 mi · 2 min · East Ormsby Street
-
30
Continue on State Highway 82
24.5 mi · 36 min · State Highway 82
-
31
Keep slight right
85 m · 5 sec
-
32
Take the ramp right
1756 ft · 43 sec
-
33
Merge slight left
23.5 mi · 25 min
-
34
Keep slight left to continue on I 90 West: Tomah, La Crosse
39.1 mi · 42 min
-
35
Take the exit slight right toward WI 16: La Crosse, Onalaska
1636 ft · 42 sec
-
36
At the end of the road, turn left
4.9 mi · 9 min
-
37
Continue on Losey Boulevard North
2575 ft · 2 min · Losey Boulevard North
-
38
Turn right onto Main Street
1.1 km · 2 min · Main Street
-
39
Turn left onto 16th Street South
1.3 km · 2 min · 16th Street South
-
40
Turn right onto Johnson Street
1824 ft · 1 min · Johnson Street
-
41
At the end of the road, turn right onto West Avenue South
99 m · 11 sec · West Avenue South
-
42
Arrive at your destination
0 m · 1 sec · West Avenue South
Car Route Details
A richer read on the saved driving route between Mishicot and La Crosse.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 41 South
Merge slight left
49.1 mi · 00h 53m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Partly Sunny leaving Mishicot and Mostly Sunny then Chance Showers And Thunderstorms near La Crosse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mishicot to La Crosse?
The road trip is about 220.2 miles (354.4 km) and usually takes 04h 04m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Mecan is a useful midpoint, sitting about 115.8 miles from Mishicot and 104.4 miles from La Crosse.
How much longer is the road route than the straight-line distance?
The direct path is about 181.3 miles (291.8 km), while the road route adds roughly 38.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:52 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $29.30 one way or $58.60 round trip. Estimated CO2 is about 69.1 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around Mishicot and Mostly Sunny then Chance Showers And Thunderstorms near La Crosse.
Stop Ideas Near Mecan
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Mecan.
Westfield, WI
Portage
Waupun, WI
Wisconsin Dells
Flight Path Map
This map shows the direct air route between Mishicot and La Crosse. Straight-line distance: 181.31 mi (291.79 km).
#1 Mishicot
Village in Manitowoc County, Wisconsin
| Population | 1,261 |
| Coordinates | 44.2391600, -87.6411900 |
| Altitude | 184 |
| Country | United States |
#2 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
End: West Avenue South (-91.239623, 43.801338)
Estimated Travel Time
Distance: 354 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 20m |
| 40 mph (64.37 km/h) | 05h 30m |
| 50 mph (80.47 km/h) | 04h 24m |
| 60 mph (96.56 km/h) | 03h 40m |
| 70 mph (112.65 km/h) | 03h 08m |
| 80 mph (129 km/h) | 02h 44m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $29.30 | $58.60 |
| Mid-grade | $4.25 | $33.05 | $66.09 |
| Premium | $4.65 | $36.16 | $72.32 |
| Diesel | $5.30 | $41.21 | $82.42 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.