How far is Miami, FL from Mayo, FL?
The driving distance from Miami, FL to Mayo, FL is about 394 miles (634.1 km), with a travel time of about 07h 25m by car.
- The straight-line flight distance is about 347.1 miles (558.6 km).
- For a round trip, plan for roughly 14h 50m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 25m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
A city in Osceola County, Florida.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Miami and Mayo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Miami and Mayo.
-
1
Start on North Miami Avenue
152 m · 17 sec · North Miami Avenue
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2
Take the ramp slight right toward I 95
144 m · 11 sec
-
3
Keep slight right to continue on I 95 North
2593 ft · 1 min
-
4
Merge slight right
2.1 mi · 3 min
-
5
Keep slight right
7.8 mi · 10 min
-
6
Take the exit slight left toward SR 826 West: Florida's Turnpike Toll
1.3 km · 2 min
-
7
Keep slight left to continue on Florida's Turnpike
2242 ft · 55 sec
-
8
Merge slight right onto Florida's Turnpike
263.9 mi · 4 hr 47 min · Florida's Turnpike
-
9
Keep slight left to continue on Florida's Turnpike
1281 ft · 16 sec · Florida's Turnpike
-
10
Merge slight left
71.6 mi · 1 hr 17 min
-
11
Take the exit slight right toward US 441: Alachua, High Springs
1040 ft · 59 sec
-
12
Turn right onto ML King Memorial Highway
4 mi · 5 min · ML King Memorial Highway
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13
Continue on Santa Fe Boulevard
1.4 km · 1 min · Santa Fe Boulevard
-
14
Turn slight left onto Northeast 1st Avenue
3020 ft · 1 min · Northeast 1st Avenue
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15
Continue on Northwest 1st Avenue
40.3 mi · 54 min · Northwest 1st Avenue
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16
Continue on Main Street
1.1 km · 1 min · Main Street
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17
Arrive at your destination
0 m · 1 sec · Main Street
Car Route Details
A richer read on the saved driving route between Miami and Mayo.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Merge slight right onto Florida's Turnpike
264 mi · 04h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Cloudy leaving Miami and Sunny near Mayo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Miami to Mayo?
The road trip is about 394 miles (634.1 km) and usually takes 07h 25m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Saint Cloud is a useful midpoint, sitting about 197.3 miles from Miami and 196.7 miles from Mayo.
How much longer is the road route than the straight-line distance?
The direct path is about 347.1 miles (558.6 km), while the road route adds roughly 46.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $57.66 one way or $115.31 round trip. Estimated CO2 is about 123.5 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Cloudy around Miami and Sunny near Mayo.
Stop Ideas Near Saint Cloud
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Cloud.
Kissimmee
Orlando Health/Amtrak
Winter Park
Winter Haven
Flight Path Map
This map shows the direct air route between Miami and Mayo. Straight-line distance: 347.13 mi (558.65 km).
#1 Miami
The most populous city in Florida, Miami is a major center for tourism, finance, and culture.
| Population | 471,525 |
| Coordinates | 25.7742700, -80.1936600 |
| Altitude | 2 |
| Country | United States |
#2 Mayo
Municipality in Lafayette, Florida, USA
| Population | 1,289 |
| Coordinates | 30.0530000, -83.1748600 |
| Altitude | 27 |
| Country | United States |
End: Mayo (-83.17486, 30.053)
Estimated Travel Time
Distance: 634 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 07m |
| 40 mph (64.37 km/h) | 09h 51m |
| 50 mph (80.47 km/h) | 07h 52m |
| 60 mph (96.56 km/h) | 06h 33m |
| 70 mph (112.65 km/h) | 05h 37m |
| 80 mph (129 km/h) | 04h 54m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $57.66 | $115.31 |
| Mid-grade | $4.60 | $63.88 | $127.77 |
| Premium | $4.90 | $68.05 | $136.11 |
| Diesel | $4.35 | $60.46 | $120.93 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.