How far is Medford, OR from Sisters, OR?
The driving distance from Medford, OR to Sisters, OR is about 194.4 miles (312.8 km), with a travel time of about 04h 28m by car.
- The straight-line flight distance is about 151.2 miles (243.4 km).
- For a round trip, plan for roughly 08h 56m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM PDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 28m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Oregon, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Chance Rain And Snow
Driving Route Map
The map below follows the saved road route between Medford and Sisters.
Turn-by-Turn Driving Directions
Step-by-step road directions between Medford and Sisters.
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1
Start on North Fir Street
580 ft · 18 sec · North Fir Street
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2
Turn right onto West 4th Street
2226 ft · 54 sec · West 4th Street
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3
Continue on Biddle Road
1.3 mi · 2 min · Biddle Road
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4
Take the ramp right
1221 ft · 36 sec
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5
Merge slight left onto Crater Lake Highway
2251 ft · 52 sec · Crater Lake Highway
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6
Turn straight onto Rogue Valley Expressway
4.5 mi · 6 min · Rogue Valley Expressway
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7
At the end of the road, turn left onto Crater Lake Highway
49.6 mi · 1 hr 12 min · Crater Lake Highway
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8
Turn straight onto Diamond Lake Highway
23.8 mi · 35 min · Diamond Lake Highway
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9
At the end of the road, turn right onto North Umpqua Highway
2.9 mi · 4 min · North Umpqua Highway
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10
Keep slight left to continue on North Umpqua Highway
66 m · 4 sec · North Umpqua Highway
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11
Continue on East Diamond Lake Highway
8.4 mi · 12 min · East Diamond Lake Highway
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12
Continue on State Highway 138
6.3 mi · 9 min · State Highway 138
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13
Turn left onto The Dalles-California Highway
71.2 mi · 1 hr 29 min · The Dalles-California Highway
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14
Continue on Bend Parkway
3.8 mi · 6 min · Bend Parkway
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15
Take the exit slight right toward Downtown Bend
1040 ft · 27 sec
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16
Continue on Northeast Division Street
3116 ft · 1 min · Northeast Division Street
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17
Continue on Division Street
676 ft · 16 sec · Division Street
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18
Turn left onto Northeast 3rd Street
1 mi · 2 min · Northeast 3rd Street
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19
Turn slight right onto McKenzie-Bend Highway
1.3 km · 59 sec · McKenzie-Bend Highway
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20
Enter the roundabout and take exit 2 toward McKenzie-Bend Highway
41 m · 2 sec · McKenzie-Bend Highway
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21
Exit the roundabout onto McKenzie-Bend Highway
2082 ft · 36 sec · McKenzie-Bend Highway
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22
Enter the roundabout and take exit 2 toward McKenzie-Bend Highway
40 m · 2 sec · McKenzie-Bend Highway
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23
Exit the roundabout onto McKenzie-Bend Highway
1.2 km · 1 min · McKenzie-Bend Highway
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24
Enter the roundabout and take exit 2 toward McKenzie-Bend Highway
35 m · 1 sec · McKenzie-Bend Highway
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25
Exit the roundabout onto McKenzie-Bend Highway
2 mi · 3 min · McKenzie-Bend Highway
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26
Enter the roundabout and take exit 2 toward McKenzie-Bend Highway
38 m · 2 sec · McKenzie-Bend Highway
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27
Exit the roundabout onto McKenzie-Bend Highway
15 mi · 19 min · McKenzie-Bend Highway
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28
Enter the roundabout and take exit 2 toward the route
50 m · 2 sec
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29
Exit the roundabout
1460 ft · 45 sec
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30
Turn left
42 m · 10 sec
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31
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Medford and Sisters.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
The Dalles-California Highway
Turn left onto The Dalles-California Highway
71.2 mi · 01h 29m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Medford and Chance Rain And Snow near Sisters.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Medford to Sisters?
The road trip is about 194.4 miles (312.8 km) and usually takes 04h 28m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Chiloquin is a useful midpoint, sitting about 97.2 miles from Medford and 97.2 miles from Sisters.
How much longer is the road route than the straight-line distance?
The direct path is about 151.2 miles (243.4 km), while the road route adds roughly 43.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM PDT. If you want a more comfortable same-day return, try to leave by 8:04 AM PDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $33.96 one way or $67.93 round trip. Estimated CO2 is about 61 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Medford and Chance Rain And Snow near Sisters.
Stop Ideas Near Chiloquin
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Chiloquin.
Klamath Falls, OR
Klamath Falls station
Crater Lake, OR
Chemult
Flight Path Map
This map shows the direct air route between Medford and Sisters. Straight-line distance: 151.22 mi (243.37 km).
#1 Medford
The most populous city in Jackson County, Oregon.
| Population | 83,412 |
| Coordinates | 42.3265200, -122.8755900 |
| Altitude | 421 |
| Country | United States |
#2 Sisters
City in Oregon, USA
| Population | 2,811 |
| Coordinates | 44.2909500, -121.5492100 |
| Altitude | 973 |
| Country | United States |
End: Sisters (-121.54921, 44.29095)
Estimated Travel Time
Distance: 313 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 28m |
| 40 mph (64.37 km/h) | 04h 51m |
| 50 mph (80.47 km/h) | 03h 53m |
| 60 mph (96.56 km/h) | 03h 14m |
| 70 mph (112.65 km/h) | 02h 46m |
| 80 mph (129 km/h) | 02h 25m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.95 | $33.96 | $67.93 |
| Mid-grade | $5.34 | $36.62 | $73.24 |
| Premium | $5.57 | $38.18 | $76.37 |
| Diesel | $6.37 | $43.67 | $87.34 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Oregon · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.