How far is Madison, MS from Saltillo, MS?
The driving distance from Madison, MS to Saltillo, MS is about 205.4 miles (330.5 km), with a travel time of about 03h 55m by car.
- The straight-line flight distance is about 156 miles (251.1 km).
- For a round trip, plan for roughly 07h 51m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 55m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Mississippi
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Madison and Saltillo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Madison and Saltillo.
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1
Start on Depot Drive
11 m · 3 sec · Depot Drive
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2
Turn right onto Main Street
2421 ft · 1 min · Main Street
-
3
At the end of the road, turn left onto Main Street
1.2 km · 2 min · Main Street
-
4
Take the ramp slight right
2318 ft · 57 sec
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5
Merge slight left
102.4 mi · 1 hr 50 min
-
6
Take the exit slight right toward MS 7 North: Coffeeville
36.4 mi · 42 min
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7
Enter the roundabout and take exit 2 toward MS 7 North: Oxford
52 m · 2 sec
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8
Exit the roundabout onto MS 7 North: Oxford
6.2 mi · 8 min
-
9
Take the exit slight right
1737 ft · 42 sec
-
10
Merge slight left
1.6 km · 1 min
-
11
Continue straight
21.2 mi · 24 min
-
12
Continue straight
9 mi · 10 min
-
13
Take the exit slight right toward MS 9: Pontotoc, Sherman
1830 ft · 50 sec
-
14
Keep slight left to continue on MS 9 North: Sherman
72 m · 12 sec
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15
Turn left
9.8 mi · 12 min
-
16
Take the exit right toward I-22 East, US 78 East: Tupelo
1159 ft · 28 sec
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17
Merge slight left
9.2 mi · 10 min
-
18
Take the exit slight right toward US 45:north: Corinth
1315 ft · 32 sec
-
19
Merge slight left
5.6 mi · 6 min
-
20
Take the exit slight right
1824 ft · 45 sec
-
21
Keep slight right
104 m · 8 sec
-
22
Turn straight
1088 ft · 22 sec
-
23
Turn slight right
138 m · 20 sec
-
24
Continue straight
115 m · 20 sec
-
25
Turn left onto Kyle Avenue
1597 ft · 1 min · Kyle Avenue
-
26
At the end of the road, turn left
2751 ft · 2 min
-
27
Continue on East Mobile Street
153 m · 10 sec · East Mobile Street
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28
Arrive at your destination
0 m · 1 sec · East Mobile Street
Car Route Details
A richer read on the saved driving route between Madison and Saltillo.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Main Street
Merge slight left
102 mi · 01h 50m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Madison and Sunny near Saltillo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Madison to Saltillo?
The road trip is about 205.4 miles (330.5 km) and usually takes 03h 55m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Grenada is a useful midpoint, sitting about 102.8 miles from Madison and 102.6 miles from Saltillo.
How much longer is the road route than the straight-line distance?
The direct path is about 156 miles (251.1 km), while the road route adds roughly 49.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:08 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.46 one way or $54.91 round trip. Estimated CO2 is about 64.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Madison and Sunny near Saltillo.
Stop Ideas Near Grenada
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Grenada.
Greenwood
Yazoo City
Flight Path Map
This map shows the direct air route between Madison and Saltillo. Straight-line distance: 156 mi (251.05 km).
#1 Madison
City in Madison County, Florida, United States
| Population | 25,701 |
| Coordinates | 32.4618100, -90.1153600 |
| Altitude | 103 |
| Country | United States |
#2 Saltillo
Human settlement in Lee County, Mississippi, United States of America
| Population | 5,071 |
| Coordinates | 34.3764900, -88.6817200 |
| Altitude | 98 |
| Country | United States |
End: Saltillo (-88.68172, 34.37649)
Estimated Travel Time
Distance: 330 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 50m |
| 40 mph (64.37 km/h) | 05h 08m |
| 50 mph (80.47 km/h) | 04h 06m |
| 60 mph (96.56 km/h) | 03h 25m |
| 70 mph (112.65 km/h) | 02h 56m |
| 80 mph (129 km/h) | 02h 33m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $27.46 | $54.91 |
| Mid-grade | $4.26 | $30.88 | $61.76 |
| Premium | $4.63 | $33.53 | $67.06 |
| Diesel | $5.42 | $39.26 | $78.52 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.