How far is Madison, MS from Biloxi, MS?
The driving distance from Madison, MS to Biloxi, MS is about 178.8 miles (287.8 km), with a travel time of about 02h 58m by car.
- The straight-line flight distance is about 160.1 miles (257.6 km).
- For a round trip, plan for roughly 05h 57m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 58m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Lamar County, Mississippi, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Partly Sunny
Driving Route Map
The map below follows the saved road route between Madison and Biloxi.
Turn-by-Turn Driving Directions
Step-by-step road directions between Madison and Biloxi.
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1
Start on Depot Drive
11 m · 7 sec · Depot Drive
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2
Turn left onto Main Street
1177 ft · 35 sec · Main Street
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3
Turn right onto United States Highway 51
4.4 mi · 7 min · United States Highway 51
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4
Turn left onto I-55 Frontage Road
1575 ft · 29 sec · I-55 Frontage Road
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5
Continue on I- 55 North Frontage Road
135 m · 8 sec · I- 55 North Frontage Road
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6
Take the ramp straight
1274 ft · 31 sec
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7
Merge slight left
8.2 mi · 10 min
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8
Take the exit slight right toward I 20 East, US 49 South: Meridian, Hattiesburg
1.5 km · 1 min
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9
Keep slight right to continue on Richland, Hattiesburg
1.2 km · 2 min
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10
Merge slight left onto Highway 49 South
80.3 mi · 1 hr 37 min · Highway 49 South
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11
Continue straight
2294 ft · 36 sec
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12
Continue straight
1.1 mi · 2 min
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13
Take the exit slight right toward I 59 South: New Orleans, Gulf Coast
1914 ft · 36 sec
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14
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
7.7 mi · 8 min · Lance Corporal Roy M Wheat Memorial Highway
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15
Take the exit slight right toward US 98 East: Lucedale, Mobile
3.2 mi · 4 min
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16
Take the exit slight right toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
1558 ft · 44 sec
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17
Keep slight left to continue on Multi Purpose Center, Hattiesburg
833 ft · 28 sec
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18
Turn right
41.9 mi · 49 min
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19
Take the exit slight right toward MS 67 South: D'Iberville, Biloxi
1.2 km · 1 min
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20
Continue on Biloxi-D'Iberville Scenic Expressway
20.5 mi · 24 min · Biloxi-D'Iberville Scenic Expressway
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21
Continue straight
3.2 mi · 4 min
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22
Take the exit slight right toward Division Street
1852 ft · 47 sec
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23
Turn left onto Division Street
3090 ft · 2 min · Division Street
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24
Turn right onto Main Street
2572 ft · 1 min · Main Street
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25
Turn left onto Howard Avenue
28 m · 3 sec · Howard Avenue
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26
Arrive at your destination
0 m · 1 sec · Howard Avenue
Car Route Details
A richer read on the saved driving route between Madison and Biloxi.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Highway 49 South
Merge slight left onto Highway 49 South
80.3 mi · 01h 37m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Partly Sunny leaving Madison and Partly Sunny near Biloxi.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Madison to Biloxi?
The road trip is about 178.8 miles (287.8 km) and usually takes 02h 58m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Sumrall is a useful midpoint, sitting about 88.3 miles from Madison and 90.5 miles from Biloxi.
How much longer is the road route than the straight-line distance?
The direct path is about 160.1 miles (257.6 km), while the road route adds roughly 18.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 12:32 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $23.90 one way or $47.79 round trip. Estimated CO2 is about 56.1 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around Madison and Partly Sunny near Biloxi.
Stop Ideas Near Sumrall
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Sumrall.
Hattiesburg, MS
Hattiesburg station
Laurel station
Brookhaven
Flight Path Map
This map shows the direct air route between Madison and Biloxi. Straight-line distance: 160.1 mi (257.65 km).
#1 Madison
City in Madison County, Florida, United States
| Population | 25,701 |
| Coordinates | 32.4618100, -90.1153600 |
| Altitude | 103 |
| Country | United States |
#2 Biloxi
The most populous city in Harrison County, Mississippi.
| Population | 46,127 |
| Coordinates | 30.3960300, -88.8853100 |
| Altitude | 6 |
| Country | United States |
End: Howard Avenue (-88.885298, 30.396088)
Estimated Travel Time
Distance: 288 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 57m |
| 40 mph (64.37 km/h) | 04h 28m |
| 50 mph (80.47 km/h) | 03h 34m |
| 60 mph (96.56 km/h) | 02h 58m |
| 70 mph (112.65 km/h) | 02h 33m |
| 80 mph (129 km/h) | 02h 13m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $23.90 | $47.79 |
| Mid-grade | $4.26 | $26.87 | $53.75 |
| Premium | $4.63 | $29.18 | $58.37 |
| Diesel | $5.42 | $34.17 | $68.34 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.