How far is Madison, MS from Picayune, MS?
The driving distance from Madison, MS to Picayune, MS is about 161 miles (259.1 km), with a travel time of about 03h 12m by car.
- The straight-line flight distance is about 136.3 miles (219.3 km).
- For a round trip, plan for roughly 06h 24m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 12m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Mississippi, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Chance Rain Showers then Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Madison and Picayune.
Turn-by-Turn Driving Directions
Step-by-step road directions between Madison and Picayune.
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1
Start on Depot Drive
11 m · 7 sec · Depot Drive
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2
Turn left onto Main Street
1177 ft · 35 sec · Main Street
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3
Turn right onto United States Highway 51
4.4 mi · 7 min · United States Highway 51
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4
Turn left onto I-55 Frontage Road
1575 ft · 29 sec · I-55 Frontage Road
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5
Continue on I- 55 North Frontage Road
135 m · 8 sec · I- 55 North Frontage Road
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6
Take the ramp straight
1274 ft · 31 sec
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7
Merge slight left
8.2 mi · 10 min
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8
Take the exit slight right toward I 20 East, US 49 South: Meridian, Hattiesburg
1.5 km · 1 min
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9
Keep slight right to continue on Richland, Hattiesburg
1.2 km · 2 min
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10
Merge slight left onto Highway 49 South
80.3 mi · 1 hr 37 min · Highway 49 South
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11
Continue straight
2294 ft · 36 sec
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12
Continue straight
1.1 mi · 2 min
-
13
Take the exit slight right toward I 59 South: New Orleans, Gulf Coast
1914 ft · 36 sec
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14
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
60.7 mi · 1 hr 5 min · Lance Corporal Roy M Wheat Memorial Highway
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15
Take the exit slight right toward MS 43: North Picayune
1355 ft · 33 sec
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16
Turn right onto Highway 43 North
1 mi · 2 min · Highway 43 North
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17
Turn straight
151 m · 22 sec
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18
Turn left
1.5 mi · 2 min
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19
Turn left onto East Canal Street
638 ft · 18 sec · East Canal Street
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20
Arrive at your destination
0 m · 1 sec · East Canal Street
Car Route Details
A richer read on the saved driving route between Madison and Picayune.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Highway 49 South
Merge slight left onto Highway 49 South
80.3 mi · 01h 37m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Madison and Chance Rain Showers then Mostly Cloudy near Picayune.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Madison to Picayune?
The road trip is about 161 miles (259.1 km) and usually takes 03h 12m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Seminary is a useful midpoint, sitting about 80.6 miles from Madison and 80.4 miles from Picayune.
How much longer is the road route than the straight-line distance?
The direct path is about 136.3 miles (219.3 km), while the road route adds roughly 24.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:36 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $21.51 one way or $43.02 round trip. Estimated CO2 is about 50.5 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Madison and Chance Rain Showers then Mostly Cloudy near Picayune.
Stop Ideas Near Seminary
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Seminary.
Hattiesburg, MS
Hattiesburg station
Laurel station
Brookhaven
Flight Path Map
This map shows the direct air route between Madison and Picayune. Straight-line distance: 136.24 mi (219.26 km).
#1 Madison
City in Madison County, Florida, United States
| Population | 25,701 |
| Coordinates | 32.4618100, -90.1153600 |
| Altitude | 103 |
| Country | United States |
#2 Picayune
City in Pearl River County, Mississippi, United States
| Population | 10,886 |
| Coordinates | 30.5255600, -89.6778800 |
| Altitude | 22 |
| Country | United States |
End: Picayune (-89.67788, 30.52556)
Estimated Travel Time
Distance: 259 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 21m |
| 40 mph (64.37 km/h) | 04h 01m |
| 50 mph (80.47 km/h) | 03h 13m |
| 60 mph (96.56 km/h) | 02h 41m |
| 70 mph (112.65 km/h) | 02h 18m |
| 80 mph (129 km/h) | 02h 00m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $21.51 | $43.02 |
| Mid-grade | $4.26 | $24.19 | $48.38 |
| Premium | $4.63 | $26.27 | $52.54 |
| Diesel | $5.42 | $30.76 | $61.51 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.