How far is Lakeland, FL from Key Largo, FL?
The driving distance from Lakeland, FL to Key Largo, FL is about 270.9 miles (436 km), with a travel time of about 05h 50m by car.
- The straight-line flight distance is about 224.1 miles (360.7 km).
- For a round trip, plan for roughly 11h 40m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 50m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Florida
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Slight Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Lakeland and Key Largo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Lakeland and Key Largo.
-
1
Start on East Walnut Street
85 m · 17 sec · East Walnut Street
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2
Turn left onto South Lake Avenue
82 m · 16 sec · South Lake Avenue
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3
Turn right onto East Lime Street
1878 ft · 56 sec · East Lime Street
-
4
Turn right onto Bartow Road
10.7 mi · 16 min · Bartow Road
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5
Continue on Broadway Avenue
3183 ft · 1 min · Broadway Avenue
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6
Turn left onto Van Fleet Drive
2787 ft · 1 min · Van Fleet Drive
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7
Continue straight
1427 ft · 27 sec
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8
Continue straight
10.8 mi · 14 min
-
9
Continue straight
3.7 mi · 5 min
-
10
Take the exit slight right toward US 27: Haines City, Avon Park
1128 ft · 31 sec
-
11
Keep slight right
83 m · 7 sec
-
12
Merge slight left onto US 27
22.6 mi · 28 min · US 27
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13
Continue straight
10.3 mi · 15 min
-
14
Continue straight
55.1 mi · 1 hr 7 min
-
15
Merge slight left
1177 ft · 18 sec
-
16
Turn slight right
103 m · 4 sec
-
17
Continue straight
32.1 mi · 43 min
-
18
Continue straight
40.1 mi · 48 min
-
19
Continue straight
10.4 mi · 13 min
-
20
Keep slight right
8.6 mi · 11 min
-
21
Take the exit right toward Florida's Turnpike South: Homestead, Key West
1324 ft · 32 sec
-
22
Merge slight left onto Homestead Extension of Florida's Turnpike
34.5 mi · 41 min · Homestead Extension of Florida's Turnpike
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23
Keep slight left
2930 ft · 1 min
-
24
Merge slight left onto Dixie Highway
19.2 mi · 27 min · Dixie Highway
-
25
Continue on Overseas Highway
9.3 mi · 16 min · Overseas Highway
-
26
Continue on Overseas Highway
138 m · 28 sec · Overseas Highway
-
27
Turn right onto Harbor Drive
94 m · 14 sec · Harbor Drive
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28
Arrive at your destination
0 m · 1 sec · Harbor Drive
Car Route Details
A richer read on the saved driving route between Lakeland and Key Largo.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 27
Continue straight
55.1 mi · 01h 07m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Lakeland and Slight Chance Rain Showers near Key Largo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Lakeland to Key Largo?
The road trip is about 270.9 miles (436 km) and usually takes 05h 50m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Clewiston is a useful midpoint, sitting about 135.7 miles from Lakeland and 135.2 miles from Key Largo.
How much longer is the road route than the straight-line distance?
The direct path is about 224.1 miles (360.7 km), while the road route adds roughly 46.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 5:20 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $39.65 one way or $79.31 round trip. Estimated CO2 is about 85 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Lakeland and Slight Chance Rain Showers near Key Largo.
Stop Ideas Near Clewiston
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Clewiston.
Okeechobee
West Palm Beach
Delray Beach
Deerfield Beach
Flight Path Map
This map shows the direct air route between Lakeland and Key Largo. Straight-line distance: 224.16 mi (360.75 km).
#1 Lakeland
The most populous city in Polk County, Florida.
| Population | 115,283 |
| Coordinates | 28.0394700, -81.9498000 |
| Altitude | 60 |
| Country | United States |
#2 Key Largo
Census designated place in Florida, United States
| Population | 10,433 |
| Coordinates | 25.0865200, -80.4472800 |
| Altitude | 2 |
| Country | United States |
End: Key Largo (-80.44728, 25.08652)
Estimated Travel Time
Distance: 436 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 01m |
| 40 mph (64.37 km/h) | 06h 46m |
| 50 mph (80.47 km/h) | 05h 25m |
| 60 mph (96.56 km/h) | 04h 30m |
| 70 mph (112.65 km/h) | 03h 52m |
| 80 mph (129 km/h) | 03h 22m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $39.65 | $79.31 |
| Mid-grade | $4.60 | $43.94 | $87.88 |
| Premium | $4.90 | $46.81 | $93.61 |
| Diesel | $4.35 | $41.59 | $83.17 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.