How far is La Crosse, WI from Florence, WI?
The driving distance from La Crosse, WI to Florence, WI is about 265.9 miles (427.9 km), with a travel time of about 06h 19m by car.
- The straight-line flight distance is about 207 miles (333.2 km).
- For a round trip, plan for roughly 12h 38m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 19m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny then Chance Showers And Thunderstorms
Mostly Sunny
Driving Route Map
The map below follows the saved road route between La Crosse and Florence.
Turn-by-Turn Driving Directions
Step-by-step road directions between La Crosse and Florence.
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1
Start on West Avenue South
1.1 km · 2 min · West Avenue South
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2
Turn right
107 m · 12 sec
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3
Turn straight onto Main Street
1.5 km · 2 min · Main Street
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4
Turn left onto Losey Boulevard North
2555 ft · 1 min · Losey Boulevard North
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5
Continue straight
4.5 mi · 8 min
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6
Take the ramp slight right
2171 ft · 53 sec
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7
Merge slight left
38.6 mi · 41 min
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8
Take the exit slight left toward I 94 West: Eau Claire, Saint Paul
1.3 km · 55 sec
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9
Merge slight right
2.9 mi · 3 min
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10
Take the exit slight right toward US 12, WI 21: Tomah, Necedah
1385 ft · 34 sec
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11
Turn right onto East McCoy Boulevard
1738 ft · 33 sec · East McCoy Boulevard
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12
Continue on State Highway 21
4 mi · 6 min · State Highway 21
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13
Turn left onto State Highway 173
23.6 mi · 34 min · State Highway 173
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14
At the end of the road, turn left onto State Highway 173
1.3 mi · 2 min · State Highway 173
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15
Continue on State Highway 80
125 m · 9 sec · State Highway 80
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16
Turn right onto State Highway 173
9.1 mi · 13 min · State Highway 173
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17
Continue on County Highway G
2 mi · 3 min · County Highway G
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18
At the end of the road, turn right onto State Highway 54
2.1 mi · 3 min · State Highway 54
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19
Continue on Letendre Avenue
1.4 mi · 2 min · Letendre Avenue
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20
At the end of the road, turn left onto Wisconsin River Drive
1.6 mi · 2 min · Wisconsin River Drive
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21
Continue on 2nd Avenue South
1.3 mi · 2 min · 2nd Avenue South
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22
Enter the roundabout and take exit 1 toward 2nd Avenue South
20 m · 1 sec · 2nd Avenue South
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23
Exit the roundabout onto 2nd Avenue South
2782 ft · 1 min · 2nd Avenue South
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24
Turn left onto West Riverview Expressway
1.3 km · 2 min · West Riverview Expressway
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25
Continue straight
14.3 mi · 21 min
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26
Take the ramp right
1753 ft · 43 sec
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27
Merge slight left onto US Highway 10
3.8 mi · 4 min · US Highway 10
-
28
Take the exit slight right toward WI 34, CTH P, CTH HH: Knowlton, Stevens Point
1508 ft · 37 sec
-
29
Turn left onto State Highway 134
789 ft · 21 sec · State Highway 134
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30
Continue on WI 34
1199 ft · 23 sec · WI 34
-
31
Continue on State Highway 34
9.5 mi · 13 min · State Highway 34
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32
Enter the roundabout and take exit 2 toward State Highway 34
40 m · 2 sec · State Highway 34
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33
Exit the roundabout onto State Highway 34
1834 ft · 39 sec · State Highway 34
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34
Take the ramp left
1704 ft · 42 sec
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35
Merge slight left
11.4 mi · 12 min
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36
Take the exit slight right toward WI 29 East: Weston, Green Bay
1.5 km · 1 min
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37
Merge slight left
2.5 mi · 3 min
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38
Take the exit slight right toward CTH X: Weston, Camp Phillips Road
1378 ft · 34 sec
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39
Keep slight left
54 m · 6 sec
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40
Turn left onto Camp Phillips Road
3.6 mi · 7 min · Camp Phillips Road
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41
Continue on County Road X
2.9 mi · 5 min · County Road X
-
42
At the end of the road, turn right onto State Highway 52
20.9 mi · 29 min · State Highway 52
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43
At the end of the road, turn left
3.6 mi · 5 min
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44
Continue on South Superior Street
5.7 mi · 10 min · South Superior Street
-
45
Turn right onto 5th Avenue
1 km · 2 min · 5th Avenue
-
46
Continue on Langlade Road
2 mi · 5 min · Langlade Road
-
47
Continue on State Highway 52
2.9 mi · 4 min · State Highway 52
-
48
Continue on State Highway 52
4.9 mi · 7 min · State Highway 52
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49
Continue on State Highway 52
10.8 mi · 16 min · State Highway 52
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50
At the end of the road, turn right onto State Highway 55
671 ft · 14 sec · State Highway 55
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51
Turn left onto State Highway 52
16.9 mi · 24 min · State Highway 52
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52
At the end of the road, turn left onto State Highway 32
7.9 mi · 12 min · State Highway 32
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53
At the end of the road, turn right onto Pine Street
113 m · 18 sec · Pine Street
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54
Turn left onto Linden Street
1912 ft · 1 min · Linden Street
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55
Turn right onto Mill Street
120 m · 19 sec · Mill Street
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56
Turn left onto Beech Street
2648 ft · 2 min · Beech Street
-
57
Continue on US Highway 8
16.2 mi · 22 min · US Highway 8
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58
Turn left onto State Highway 101
4.9 mi · 7 min · State Highway 101
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59
Continue on State HIghway 101
4.1 mi · 6 min · State HIghway 101
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60
Continue on State Highway 101
12.3 mi · 18 min · State Highway 101
-
61
At the end of the road, turn right onto State Highway 70/101
2.4 mi · 4 min · State Highway 70/101
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62
Turn right
1597 ft · 49 sec
-
63
Turn right onto Quinnesec Street
27 m · 2 sec · Quinnesec Street
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64
Arrive at your destination
0 m · 1 sec · Quinnesec Street
Car Route Details
A richer read on the saved driving route between La Crosse and Florence.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Losey Boulevard North
Merge slight left
38.6 mi · 00h 41m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny then Chance Showers And Thunderstorms leaving La Crosse and Mostly Sunny near Florence.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from La Crosse to Florence?
The road trip is about 265.9 miles (427.9 km) and usually takes 06h 19m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Evergreen is a useful midpoint, sitting about 132.8 miles from La Crosse and 133.1 miles from Florence.
How much longer is the road route than the straight-line distance?
The direct path is about 207 miles (333.2 km), while the road route adds roughly 58.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.37 one way or $70.74 round trip. Estimated CO2 is about 83.4 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny then Chance Showers And Thunderstorms around La Crosse and Mostly Sunny near Florence.
Stop Ideas Near Evergreen
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Evergreen.
Wausau, WI
Wausau, Wisconsin
Stevens Point, Wisconsin
Stevens Point, WI
Flight Path Map
This map shows the direct air route between La Crosse and Florence. Straight-line distance: 207.05 mi (333.22 km).
#1 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
#2 Florence
Civil town in Florence County, Wisconsin
| Population | 1,945 |
| Coordinates | 45.9221800, -88.2518000 |
| Altitude | 398 |
| Country | United States |
End: Florence (-88.2518, 45.92218)
Estimated Travel Time
Distance: 428 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 51m |
| 40 mph (64.37 km/h) | 06h 38m |
| 50 mph (80.47 km/h) | 05h 19m |
| 60 mph (96.56 km/h) | 04h 25m |
| 70 mph (112.65 km/h) | 03h 47m |
| 80 mph (129 km/h) | 03h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $35.37 | $70.74 |
| Mid-grade | $4.25 | $39.89 | $79.79 |
| Premium | $4.65 | $43.65 | $87.31 |
| Diesel | $5.30 | $49.75 | $99.50 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.