How far is La Crosse, WI from Clayton, WI?
The driving distance from La Crosse, WI to Clayton, WI is about 147.6 miles (237.6 km), with a travel time of about 03h 29m by car.
- The straight-line flight distance is about 115.2 miles (185.4 km).
- For a round trip, plan for roughly 06h 59m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 29m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Buffalo County, Wisconsin, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny then Chance Showers And Thunderstorms
Partly Sunny then Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between La Crosse and Clayton.
Turn-by-Turn Driving Directions
Step-by-step road directions between La Crosse and Clayton.
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1
Start on West Avenue South
12 m · 9 sec · West Avenue South
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2
Turn left onto Jackson Street
3236 ft · 2 min · Jackson Street
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3
Turn right onto 4th Street South
2639 ft · 1 min · 4th Street South
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4
Turn left onto Cass Street
1.4 mi · 3 min · Cass Street
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5
Continue on Historic Bluff Country Scenic Byway
1.7 mi · 3 min · Historic Bluff Country Scenic Byway
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6
Turn right
7.2 mi · 9 min
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7
Keep slight right to continue on US 14, US 61: Winona
1.5 mi · 2 min
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8
Continue straight
1.7 mi · 2 min
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9
Continue straight
13.2 mi · 15 min
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10
Continue straight
1131 ft · 16 sec
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11
Enter the roundabout and take exit 2 toward US 14;US 61
44 m · 2 sec · US 14;US 61
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12
Exit the rotary onto US 14;US 61
2.6 mi · 4 min · US 14;US 61
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13
Continue straight
5.3 mi · 8 min
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14
Continue on Hiawatha Pioneer Trail
2426 ft · 38 sec · Hiawatha Pioneer Trail
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15
Continue on Hiawatha Pioneer Trail/Disabled American Veterans Highway/Voyageur Highway
25.3 mi · 29 min · Hiawatha Pioneer Trail/Disabled American Veterans Highway/Voyageur Highway
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16
Turn right onto Pembroke Avenue South
1.2 km · 1 min · Pembroke Avenue South
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17
Turn left onto 4th Grant Boulevard West
633 ft · 11 sec · 4th Grant Boulevard West
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18
Turn slight right
2044 ft · 39 sec
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19
Continue on Wabasha-Nelson Bridge
1199 ft · 20 sec · Wabasha-Nelson Bridge
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20
Continue on State Highway 25
2167 ft · 37 sec · State Highway 25
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21
Continue on State Road 25
2 mi · 3 min · State Road 25
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22
Continue on North Main Street
1.1 km · 1 min · North Main Street
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23
Continue on State Road 25-35
2406 ft · 41 sec · State Road 25-35
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24
Turn slight right
946 ft · 35 sec
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25
Turn straight onto State Road 25
13.3 mi · 19 min · State Road 25
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26
Continue on West Prospect Street
1.2 mi · 3 min · West Prospect Street
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27
Turn left onto 2nd Avenue East
819 ft · 25 sec · 2nd Avenue East
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28
At the end of the road, turn right onto East Main Street
810 ft · 24 sec · East Main Street
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29
Turn left onto US Highway 10
1.7 mi · 3 min · US Highway 10
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30
Turn right onto State Highway 25
5.7 mi · 8 min · State Highway 25
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31
Continue on County Road Y
1.4 mi · 2 min · County Road Y
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32
Continue on State Highway 25
10 mi · 14 min · State Highway 25
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33
Continue on Broadway Street South
3.6 mi · 9 min · Broadway Street South
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34
Turn left
1527 ft · 39 sec
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35
Merge slight left
12.9 mi · 14 min
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36
Take the exit slight right toward WI 128: Spring Valley, Glenwood City
757 ft · 18 sec
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37
Keep slight right to continue on WI 128: Glenwood City
95 m · 9 sec
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38
Turn right onto State Highway 128
9.1 mi · 13 min · State Highway 128
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39
Continue on West Oak Street
1227 ft · 30 sec · West Oak Street
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40
Turn left onto 1st Street
2316 ft · 46 sec · 1st Street
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41
Continue on State Highway 128
5.7 mi · 10 min · State Highway 128
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42
Continue on County Highway P
5 mi · 9 min · County Highway P
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43
Continue on 20th Street
5.9 mi · 10 min · 20th Street
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44
Continue on County Highway P
1.6 mi · 3 min · County Highway P
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45
At the end of the road, turn right
1.7 mi · 3 min
-
46
Turn right onto County Highway D
707 ft · 20 sec · County Highway D
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47
Turn left onto East Clayton Avenue
71 m · 10 sec · East Clayton Avenue
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48
Arrive at your destination
0 m · 1 sec · East Clayton Avenue
Car Route Details
A richer read on the saved driving route between La Crosse and Clayton.
Turn-heavy local drive
The route has frequent decision points for its length, so lane choice and turn timing will matter more than cruising speed.
Hiawatha Pioneer Trail/Disabled American Veteran
Continue on Hiawatha Pioneer Trail/Disabled American Veterans Highway/Voyageur Highway
25.3 mi · 00h 29m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny then Chance Showers And Thunderstorms leaving La Crosse and Partly Sunny then Showers And Thunderstorms Likely near Clayton.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from La Crosse to Clayton?
The road trip is about 147.6 miles (237.6 km) and usually takes 03h 29m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Maxville is a useful midpoint, sitting about 73.8 miles from La Crosse and 73.9 miles from Clayton.
How much longer is the road route than the straight-line distance?
The direct path is about 115.2 miles (185.4 km), while the road route adds roughly 32.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:00 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $19.65 one way or $39.29 round trip. Estimated CO2 is about 46.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny then Chance Showers And Thunderstorms around La Crosse and Partly Sunny then Showers And Thunderstorms Likely near Clayton.
Stop Ideas Near Maxville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Maxville.
Menomonie, WI
Red Wing station
Eau Claire, WI
Eau Claire, WI
Flight Path Map
This map shows the direct air route between La Crosse and Clayton. Straight-line distance: 115.23 mi (185.45 km).
#1 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
#2 Clayton
Village in Polk County, Wisconsin
| Population | 4,227 |
| Coordinates | 45.3313500, -92.1713000 |
| Altitude | 369 |
| Country | United States |
End: Clayton (-92.1713, 45.33135)
Estimated Travel Time
Distance: 238 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 55m |
| 40 mph (64.37 km/h) | 03h 41m |
| 50 mph (80.47 km/h) | 02h 57m |
| 60 mph (96.56 km/h) | 02h 27m |
| 70 mph (112.65 km/h) | 02h 06m |
| 80 mph (129 km/h) | 01h 50m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $19.65 | $39.29 |
| Mid-grade | $4.25 | $22.16 | $44.32 |
| Premium | $4.65 | $24.25 | $48.49 |
| Diesel | $5.30 | $27.63 | $55.27 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.