How far is Knoxville, TN from Medina, TN?
The driving distance from Knoxville, TN to Medina, TN is about 306.7 miles (493.6 km), with a travel time of about 05h 43m by car.
- The straight-line flight distance is about 271.9 miles (437.6 km).
- For a round trip, plan for roughly 11h 27m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 43m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Wilson County, Tennessee, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Knoxville and Medina.
Turn-by-Turn Driving Directions
Step-by-step road directions between Knoxville and Medina.
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1
Start on Henley Street
1056 ft · 20 sec · Henley Street
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2
Continue on Henley Street
727 ft · 14 sec · Henley Street
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3
Turn slight left onto Western Avenue
1.1 km · 1 min · Western Avenue
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4
Turn left onto Ailor Avenue
2326 ft · 43 sec · Ailor Avenue
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5
Take the ramp straight toward I 40 West, I 75 South
1637 ft · 40 sec
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6
Merge slight left
18.3 mi · 21 min
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7
Keep slight right to continue on Nashville
154.8 mi · 2 hr 47 min
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8
Keep slight right to continue on I 24 West, I 40 West: Nashville
2.1 mi · 3 min
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9
Keep slight left to continue on I 40 West: Huntsville, Memphis
2263 ft · 43 sec
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10
Merge slight right onto Downtown Loop
1 km · 52 sec · Downtown Loop
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11
Continue on Downtown Loop
2.3 mi · 3 min · Downtown Loop
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12
Keep slight left to continue on I 40 West: Memphis
114.2 mi · 2 hr 3 min
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13
Take the exit slight right toward SR 152
1038 ft · 25 sec
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14
Turn right onto Law Road
1.2 mi · 2 min · Law Road
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15
Turn left onto Spring Creek Law Road
3.8 mi · 7 min · Spring Creek Law Road
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16
At the end of the road, turn left
23 m · 3 sec
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17
Turn right
6.7 mi · 12 min
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18
Turn left onto North Main Street
154 m · 17 sec · North Main Street
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19
Turn left onto West Avenue
42 m · 7 sec · West Avenue
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20
Turn right onto Central Street
13 m · 2 sec · Central Street
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21
Arrive at your destination
0 m · 1 sec · Central Street
Car Route Details
A richer read on the saved driving route between Knoxville and Medina.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Nashville
Keep slight right to continue on Nashville
155 mi · 02h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Knoxville and Sunny near Medina.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Knoxville to Medina?
The road trip is about 306.7 miles (493.6 km) and usually takes 05h 43m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Lebanon is a useful midpoint, sitting about 153.1 miles from Knoxville and 153.6 miles from Medina.
How much longer is the road route than the straight-line distance?
The direct path is about 271.9 miles (437.6 km), while the road route adds roughly 34.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 5:32 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.80 one way or $81.60 round trip. Estimated CO2 is about 96.2 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Knoxville and Medina, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Sunny around Knoxville and Sunny near Medina.
Stop Ideas Near Lebanon
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lebanon.
Nashville, TN
Clarksville, TN
Flight Path Map
This map shows the direct air route between Knoxville and Medina. Straight-line distance: 271.92 mi (437.62 km).
#1 Knoxville
The most populous city in Tennessee.
| Population | 190,223 |
| Coordinates | 35.9606400, -83.9207400 |
| Altitude | 276 |
| Country | United States |
#2 Medina
City in Tennessee, United States
| Population | 4,379 |
| Coordinates | 35.8028500, -88.7747800 |
| Altitude | 150 |
| Country | United States |
End: Medina (-88.77478, 35.80285)
Estimated Travel Time
Distance: 494 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 13m |
| 40 mph (64.37 km/h) | 07h 40m |
| 50 mph (80.47 km/h) | 06h 08m |
| 60 mph (96.56 km/h) | 05h 06m |
| 70 mph (112.65 km/h) | 04h 22m |
| 80 mph (129 km/h) | 03h 49m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $40.80 | $81.60 |
| Mid-grade | $4.25 | $46.02 | $92.03 |
| Premium | $4.65 | $50.36 | $100.71 |
| Diesel | $5.30 | $57.39 | $114.78 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.