How far is Knoxville, TN from Lewisburg, TN?
The driving distance from Knoxville, TN to Lewisburg, TN is about 219 miles (352.5 km), with a travel time of about 04h 11m by car.
- The straight-line flight distance is about 164.7 miles (265.1 km).
- For a round trip, plan for roughly 08h 23m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 11m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town of the United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Rain Showers then Mostly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Knoxville and Lewisburg.
Turn-by-Turn Driving Directions
Step-by-step road directions between Knoxville and Lewisburg.
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1
Start on Henley Street
1056 ft · 20 sec · Henley Street
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2
Continue on Henley Street
727 ft · 14 sec · Henley Street
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3
Turn slight left onto Western Avenue
1.1 km · 1 min · Western Avenue
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4
Turn left onto Ailor Avenue
2326 ft · 43 sec · Ailor Avenue
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5
Take the ramp straight toward I 40 West, I 75 South
1637 ft · 40 sec
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6
Merge slight left
18.3 mi · 21 min
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7
Keep slight right to continue on Nashville
132.7 mi · 2 hr 23 min
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8
Take the exit slight right toward I 840 West: Memphis, Murfreesboro
1.1 mi · 1 min
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9
Continue on Tennessee National Guard Parkway
34.1 mi · 37 min · Tennessee National Guard Parkway
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10
Take the exit slight right toward US 31A, US 41A: Shelbyville, Lewisburg
2443 ft · 48 sec
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11
Turn left onto Horton Highway
2.8 mi · 4 min · Horton Highway
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12
Keep slight right to continue on Horton Highway
12.7 mi · 19 min · Horton Highway
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13
Continue on North Horton Parkway
1.1 km · 1 min · North Horton Parkway
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14
Continue on Nashville Highway
13.4 mi · 20 min · Nashville Highway
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15
Continue on Verona Avenue
2140 ft · 43 sec · Verona Avenue
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16
Continue on North 2nd Avenue
2818 ft · 56 sec · North 2nd Avenue
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17
Enter the roundabout toward North 2nd Avenue
75 m · 5 sec · North 2nd Avenue
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18
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Knoxville and Lewisburg.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
Nashville
Keep slight right to continue on Nashville
133 mi · 02h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Rain Showers then Mostly Sunny leaving Knoxville and Sunny near Lewisburg.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Knoxville to Lewisburg?
The road trip is about 219 miles (352.5 km) and usually takes 04h 11m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Baxter is a useful midpoint, sitting about 109.4 miles from Knoxville and 109.6 miles from Lewisburg.
How much longer is the road route than the straight-line distance?
The direct path is about 164.7 miles (265.1 km), while the road route adds roughly 54.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:36 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $29.15 one way or $58.30 round trip. Estimated CO2 is about 68.7 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Knoxville and Lewisburg, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Slight Chance Rain Showers then Mostly Sunny around Knoxville and Sunny near Lewisburg.
Stop Ideas Near Baxter
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Baxter.
Nashville, TN
Flight Path Map
This map shows the direct air route between Knoxville and Lewisburg. Straight-line distance: 164.75 mi (265.14 km).
#1 Knoxville
The most populous city in Tennessee.
| Population | 190,223 |
| Coordinates | 35.9606400, -83.9207400 |
| Altitude | 276 |
| Country | United States |
#2 Lewisburg
Township in eastern Union County, Pennsylvania
| Population | 12,559 |
| Coordinates | 35.4492400, -86.7888900 |
| Altitude | 225 |
| Country | United States |
End: Lewisburg (-86.78889, 35.44924)
Estimated Travel Time
Distance: 353 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 17m |
| 40 mph (64.37 km/h) | 05h 28m |
| 50 mph (80.47 km/h) | 04h 22m |
| 60 mph (96.56 km/h) | 03h 39m |
| 70 mph (112.65 km/h) | 03h 07m |
| 80 mph (129 km/h) | 02h 43m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $29.15 | $58.30 |
| Mid-grade | $4.25 | $32.88 | $65.75 |
| Premium | $4.65 | $35.98 | $71.95 |
| Diesel | $5.30 | $41.00 | $82.00 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.