How far is Knoxville, TN from Humboldt, TN?
The driving distance from Knoxville, TN to Humboldt, TN is about 319.1 miles (513.5 km), with a travel time of about 05h 54m by car.
- The straight-line flight distance is about 279.7 miles (450.2 km).
- For a round trip, plan for roughly 11h 48m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 54m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Wilson County, Tennessee, United States; suburb of Nashville, Tennessee
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Rain Showers
Mostly Cloudy then Slight Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Knoxville and Humboldt.
Turn-by-Turn Driving Directions
Step-by-step road directions between Knoxville and Humboldt.
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1
Start on Henley Street
1056 ft · 20 sec · Henley Street
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2
Continue on Henley Street
727 ft · 14 sec · Henley Street
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3
Turn slight left onto Western Avenue
1.1 km · 1 min · Western Avenue
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4
Turn left onto Ailor Avenue
2326 ft · 43 sec · Ailor Avenue
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5
Take the ramp straight toward I 40 West, I 75 South
1637 ft · 40 sec
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6
Merge slight left
18.3 mi · 21 min
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7
Keep slight right to continue on Nashville
154.8 mi · 2 hr 47 min
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8
Keep slight right to continue on I 24 West, I 40 West: Nashville
2.1 mi · 3 min
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9
Keep slight left to continue on I 40 West: Huntsville, Memphis
2263 ft · 43 sec
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10
Merge slight right onto Downtown Loop
1 km · 52 sec · Downtown Loop
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11
Continue on Downtown Loop
2.3 mi · 3 min · Downtown Loop
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12
Keep slight left to continue on I 40 West: Memphis
125.6 mi · 2 hr 16 min
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13
Take the exit slight right toward US 45: Trenton
1704 ft · 42 sec
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14
Turn right onto North Highland Avenue
4.4 mi · 8 min · North Highland Avenue
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15
Take the ramp slight right
6.4 mi · 9 min
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16
Turn left onto East Main Street
1.9 mi · 3 min · East Main Street
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17
Arrive at your destination
0 m · 1 sec · East Main Street
Car Route Details
A richer read on the saved driving route between Knoxville and Humboldt.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Nashville
Keep slight right to continue on Nashville
155 mi · 02h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Rain Showers leaving Knoxville and Mostly Cloudy then Slight Chance Rain Showers near Humboldt.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Knoxville to Humboldt?
The road trip is about 319.1 miles (513.5 km) and usually takes 05h 54m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Mount Juliet is a useful midpoint, sitting about 159.3 miles from Knoxville and 159.8 miles from Humboldt.
How much longer is the road route than the straight-line distance?
The direct path is about 279.7 miles (450.2 km), while the road route adds roughly 39.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 5:12 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $42.46 one way or $84.92 round trip. Estimated CO2 is about 100.1 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Knoxville and Humboldt, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Slight Chance Rain Showers around Knoxville and Mostly Cloudy then Slight Chance Rain Showers near Humboldt.
Stop Ideas Near Mount Juliet
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Mount Juliet.
Nashville, TN
Clarksville, TN
Flight Path Map
This map shows the direct air route between Knoxville and Humboldt. Straight-line distance: 279.75 mi (450.21 km).
#1 Knoxville
The most populous city in Tennessee.
| Population | 190,223 |
| Coordinates | 35.9606400, -83.9207400 |
| Altitude | 276 |
| Country | United States |
#2 Humboldt
City in Iowa
| Population | 8,126 |
| Coordinates | 35.8197900, -88.9159000 |
| Altitude | 111 |
| Country | United States |
End: Humboldt (-88.9159, 35.81979)
Estimated Travel Time
Distance: 514 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 37m |
| 40 mph (64.37 km/h) | 07h 58m |
| 50 mph (80.47 km/h) | 06h 22m |
| 60 mph (96.56 km/h) | 05h 19m |
| 70 mph (112.65 km/h) | 04h 33m |
| 80 mph (129 km/h) | 03h 58m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $42.46 | $84.92 |
| Mid-grade | $4.25 | $47.89 | $95.78 |
| Premium | $4.65 | $52.40 | $104.81 |
| Diesel | $5.30 | $59.72 | $119.45 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · May 01, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.