How far is Knoxville, TN from Henderson, TN?
The driving distance from Knoxville, TN to Henderson, TN is about 312.4 miles (502.8 km), with a travel time of about 05h 56m by car.
- The straight-line flight distance is about 267.3 miles (430.2 km).
- For a round trip, plan for roughly 11h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 56m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Wilson County, Tennessee
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny then Slight Chance Rain Showers
Slight Chance Rain Showers then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Knoxville and Henderson.
Turn-by-Turn Driving Directions
Step-by-step road directions between Knoxville and Henderson.
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1
Start on Henley Street
1056 ft · 20 sec · Henley Street
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2
Continue on Henley Street
727 ft · 14 sec · Henley Street
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3
Turn slight left onto Western Avenue
1.1 km · 1 min · Western Avenue
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4
Turn left onto Ailor Avenue
2326 ft · 43 sec · Ailor Avenue
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5
Take the ramp straight toward I 40 West, I 75 South
1637 ft · 40 sec
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6
Merge slight left
18.3 mi · 21 min
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7
Keep slight right to continue on Nashville
154.8 mi · 2 hr 47 min
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8
Keep slight right to continue on I 24 West, I 40 West: Nashville
2.1 mi · 3 min
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9
Keep slight left to continue on I 40 West: Huntsville, Memphis
2263 ft · 43 sec
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10
Merge slight right onto Downtown Loop
1 km · 52 sec · Downtown Loop
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11
Continue on Downtown Loop
2.3 mi · 3 min · Downtown Loop
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12
Keep slight left to continue on I 40 West: Memphis
81.7 mi · 1 hr 28 min
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13
Take the exit slight right toward US 641: Camden, Paris, Parsons
947 ft · 27 sec
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14
Keep slight left to continue on US 641: Camden, Paris, Parsons
47 m · 8 sec
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15
Turn left
19.3 mi · 22 min
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16
Turn right onto West Main Street
28.8 mi · 43 min · West Main Street
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17
Turn right onto East Main Street
2 mi · 4 min · East Main Street
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18
Turn right onto North Washington Avenue
19 m · 3 sec · North Washington Avenue
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19
Arrive at your destination
0 m · 1 sec · North Washington Avenue
Car Route Details
A richer read on the saved driving route between Knoxville and Henderson.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Nashville
Keep slight right to continue on Nashville
155 mi · 02h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny then Slight Chance Rain Showers leaving Knoxville and Slight Chance Rain Showers then Chance Showers And Thunderstorms near Henderson.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Knoxville to Henderson?
The road trip is about 312.4 miles (502.8 km) and usually takes 05h 56m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Rural Hill is a useful midpoint, sitting about 156 miles from Knoxville and 156.4 miles from Henderson.
How much longer is the road route than the straight-line distance?
The direct path is about 267.3 miles (430.2 km), while the road route adds roughly 45.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 5:06 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.56 one way or $83.11 round trip. Estimated CO2 is about 97.9 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Knoxville and Henderson, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Mostly Sunny then Slight Chance Rain Showers around Knoxville and Slight Chance Rain Showers then Chance Showers And Thunderstorms near Henderson.
Stop Ideas Near Rural Hill
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Rural Hill.
Nashville, TN
Clarksville, TN
Flight Path Map
This map shows the direct air route between Knoxville and Henderson. Straight-line distance: 267.29 mi (430.16 km).
#1 Knoxville
The most populous city in Tennessee.
| Population | 190,223 |
| Coordinates | 35.9606400, -83.9207400 |
| Altitude | 276 |
| Country | United States |
#2 Henderson
City in Chester County, Tennessee
| Population | 6,417 |
| Coordinates | 35.4392400, -88.6414400 |
| Altitude | 136 |
| Country | United States |
End: Henderson (-88.64144, 35.43924)
Estimated Travel Time
Distance: 503 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 24m |
| 40 mph (64.37 km/h) | 07h 48m |
| 50 mph (80.47 km/h) | 06h 14m |
| 60 mph (96.56 km/h) | 05h 12m |
| 70 mph (112.65 km/h) | 04h 27m |
| 80 mph (129 km/h) | 03h 53m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $41.56 | $83.11 |
| Mid-grade | $4.25 | $46.87 | $93.74 |
| Premium | $4.65 | $51.29 | $102.57 |
| Diesel | $5.30 | $58.45 | $116.90 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.