How far is Knox, NY from Buffalo, NY?
The driving distance from Knox, NY to Buffalo, NY is about 268.6 miles (432.3 km), with a travel time of about 04h 28m by car.
- The straight-line flight distance is about 242 miles (389.4 km).
- For a round trip, plan for roughly 08h 56m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 28m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in New York, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers then Partly Sunny
Driving Route Map
The map below follows the saved road route between Knox and Buffalo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Knox and Buffalo.
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1
Start on Knox Cave Road
9 m · 2 sec · Knox Cave Road
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2
Turn right onto Berne-Altamont Road
1.5 km · 2 min · Berne-Altamont Road
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3
Keep slight right to continue on Knox-Gallupville Road
1.4 km · 2 min · Knox-Gallupville Road
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4
Turn right onto Beebe Road
3.3 mi · 4 min · Beebe Road
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5
At the end of the road, turn right onto Knox Cave Road
1473 ft · 45 sec · Knox Cave Road
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6
Turn left onto West Wind Road
1.2 km · 1 min · West Wind Road
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7
Turn left onto Bozenkill Road
750 ft · 12 sec · Bozenkill Road
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8
Turn slight right onto Crow Hill Road
1.2 km · 1 min · Crow Hill Road
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9
At the end of the road, turn left onto Schoharie Turnpike
1.9 mi · 3 min · Schoharie Turnpike
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10
Turn straight onto Duanesburg Road
2 mi · 3 min · Duanesburg Road
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11
Continue on Central Bridge Road
4.9 mi · 7 min · Central Bridge Road
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12
Turn right onto Zicha Road
1.1 mi · 2 min · Zicha Road
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13
Continue on Junction Road
1.2 km · 1 min · Junction Road
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14
Keep slight left to continue on Junction Road
3004 ft · 57 sec · Junction Road
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15
Turn right onto State Highway 30A
1.8 mi · 3 min · State Highway 30A
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16
Continue straight
13.3 mi · 18 min
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17
Turn straight onto State Highway 5S
2.2 mi · 3 min · State Highway 5S
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18
Continue on East Main Street
1236 ft · 29 sec · East Main Street
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19
Take the ramp right
1152 ft · 28 sec
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20
Keep slight left to continue on I 90 West
2172 ft · 53 sec
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21
Merge slight left onto New York State Thruway
227 mi · 4 hr 23 min · New York State Thruway
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22
Take the exit slight right toward NY 33 West: Buffalo
1901 ft · 46 sec
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23
Merge slight left onto Kensington Expressway
6.4 mi · 9 min · Kensington Expressway
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24
Keep slight left to continue on Oak Street
2170 ft · 40 sec
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25
Continue on Oak Street
131 m · 14 sec · Oak Street
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26
Turn right onto Genesee Street
1172 ft · 39 sec · Genesee Street
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27
Turn right onto East Huron Street
729 ft · 34 sec · East Huron Street
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28
Turn left onto Franklin Street
716 ft · 23 sec · Franklin Street
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29
Turn right onto Genesee Street
123 m · 12 sec · Genesee Street
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30
Enter the roundabout toward Niagara Square
119 m · 12 sec · Niagara Square
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31
Arrive at your destination
0 m · 1 sec · Niagara Square
Car Route Details
A richer read on the saved driving route between Knox and Buffalo.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
New York State Thruway
Merge slight left onto New York State Thruway
227 mi · 04h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers leaving Knox and Chance Rain Showers then Partly Sunny near Buffalo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Knox to Buffalo?
The road trip is about 268.6 miles (432.3 km) and usually takes 04h 28m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Van Buren is a useful midpoint, sitting about 135.4 miles from Knox and 133.2 miles from Buffalo.
How much longer is the road route than the straight-line distance?
The direct path is about 242 miles (389.4 km), while the road route adds roughly 26.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:04 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $38.01 one way or $76.01 round trip. Estimated CO2 is about 84.2 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers around Knox and Chance Rain Showers then Partly Sunny near Buffalo.
Stop Ideas Near Van Buren
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall Cafe
Syracuse City Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Van Buren.
Empire Expo Center
William F. Walsh Regional Transportation Center
Rome station
Union Station
Flight Path Map
This map shows the direct air route between Knox and Buffalo. Straight-line distance: 241.96 mi (389.39 km).
#1 Knox
Town in Albany County, New York, United States
| Population | 2,655 |
| Coordinates | 42.6711900, -74.1156800 |
| Altitude | 376 |
| Country | United States |
#2 Buffalo
The second most populous city in New York.
| Population | 254,479 |
| Coordinates | 42.8864500, -78.8783700 |
| Altitude | 183 |
| Country | United States |
End: Niagara Square (-78.878786, 42.886515)
Estimated Travel Time
Distance: 432 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 56m |
| 40 mph (64.37 km/h) | 06h 42m |
| 50 mph (80.47 km/h) | 05h 22m |
| 60 mph (96.56 km/h) | 04h 28m |
| 70 mph (112.65 km/h) | 03h 50m |
| 80 mph (129 km/h) | 03h 21m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $38.01 | $76.01 |
| Mid-grade | $4.48 | $42.48 | $84.96 |
| Premium | $4.86 | $46.08 | $92.16 |
| Diesel | $4.69 | $44.50 | $89.00 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.