How far is Buffalo, NY from Knox, NY?
The driving distance from Buffalo, NY to Knox, NY is about 271.6 miles (437.1 km), with a travel time of about 05h 29m by car.
- The straight-line flight distance is about 242 miles (389.4 km).
- For a round trip, plan for roughly 10h 58m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 29m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in New York, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers then Partly Sunny
Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Buffalo and Knox.
Turn-by-Turn Driving Directions
Step-by-step road directions between Buffalo and Knox.
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1
Start on Niagara Square
562 ft · 19 sec · Niagara Square
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2
Exit the rotary onto Court Street
809 ft · 27 sec · Court Street
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3
Continue on Lafayette Square
114 m · 18 sec · Lafayette Square
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4
Turn left onto Washington Street
1309 ft · 45 sec · Washington Street
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5
Turn right onto Genesee Street
1429 ft · 49 sec · Genesee Street
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6
Turn left onto Elm Street
80 m · 8 sec · Elm Street
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7
Take the exit straight toward NY 33 East
972 ft · 15 sec
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8
Continue on Kensington Expressway
6.8 mi · 9 min · Kensington Expressway
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9
Take the exit slight right toward I 90 East: Niagara Falls, Albany
1644 ft · 46 sec
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10
Merge slight left onto New York State Thruway
227.2 mi · 4 hr 23 min · New York State Thruway
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11
Take the exit slight right toward NY 10: Canajoharie, Sharon Springs
2504 ft · 1 min
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12
At the end of the road, turn left onto East Main Street
1236 ft · 27 sec · East Main Street
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13
Continue on State Highway 5S
2.2 mi · 3 min · State Highway 5S
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14
Keep slight right
15.1 mi · 21 min
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15
Turn left onto Junction Road
1.3 mi · 2 min · Junction Road
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16
Continue on Zicha Road
1.1 mi · 2 min · Zicha Road
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17
Turn left
6.8 mi · 10 min
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18
Turn straight onto Schoharie Turnpike
1.9 mi · 3 min · Schoharie Turnpike
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19
Turn right onto Crow Hill Road
1.2 km · 1 min · Crow Hill Road
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20
Turn straight onto Bozenkill Road
750 ft · 12 sec · Bozenkill Road
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21
Turn right onto West Wind Road
1.2 km · 1 min · West Wind Road
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22
Turn right onto Knox Cave Road
1473 ft · 44 sec · Knox Cave Road
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23
Turn left onto Beebe Road
3.3 mi · 5 min · Beebe Road
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24
At the end of the road, turn left onto Knox-Gallupville Road
1.3 km · 2 min · Knox-Gallupville Road
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25
Continue on Knox-Gallupville Road
80 m · 7 sec · Knox-Gallupville Road
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26
Turn straight onto Berne-Altamont Road
1.5 km · 2 min · Berne-Altamont Road
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27
Turn left onto Knox Cave Road
9 m · 1 sec · Knox Cave Road
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28
Arrive at your destination
0 m · 1 sec · Knox Cave Road
Car Route Details
A richer read on the saved driving route between Buffalo and Knox.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
New York State Thruway
Merge slight left onto New York State Thruway
227 mi · 04h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Rain Showers then Partly Sunny leaving Buffalo and Chance Rain Showers near Knox.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Buffalo to Knox?
The road trip is about 271.6 miles (437.1 km) and usually takes 05h 29m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Van Buren is a useful midpoint, sitting about 135.5 miles from Buffalo and 136.1 miles from Knox.
How much longer is the road route than the straight-line distance?
The direct path is about 242 miles (389.4 km), while the road route adds roughly 29.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:02 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $38.41 one way or $76.81 round trip. Estimated CO2 is about 85.1 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers then Partly Sunny around Buffalo and Chance Rain Showers near Knox.
Stop Ideas Near Van Buren
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall Cafe
Syracuse City Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Van Buren.
Empire Expo Center
William F. Walsh Regional Transportation Center
Rome station
Union Station
Flight Path Map
This map shows the direct air route between Buffalo and Knox. Straight-line distance: 241.96 mi (389.39 km).
#1 Buffalo
The second most populous city in New York.
| Population | 254,479 |
| Coordinates | 42.8864500, -78.8783700 |
| Altitude | 183 |
| Country | United States |
#2 Knox
Town in Albany County, New York, United States
| Population | 2,655 |
| Coordinates | 42.6711900, -74.1156800 |
| Altitude | 376 |
| Country | United States |
End: Knox (-74.11568, 42.67119)
Estimated Travel Time
Distance: 437 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 02m |
| 40 mph (64.37 km/h) | 06h 47m |
| 50 mph (80.47 km/h) | 05h 25m |
| 60 mph (96.56 km/h) | 04h 31m |
| 70 mph (112.65 km/h) | 03h 52m |
| 80 mph (129 km/h) | 03h 23m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $38.41 | $76.81 |
| Mid-grade | $4.48 | $42.93 | $85.86 |
| Premium | $4.86 | $46.57 | $93.14 |
| Diesel | $4.69 | $44.97 | $89.94 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.