How far is Knowlton, WI from La Crosse, WI?
The driving distance from Knowlton, WI to La Crosse, WI is about 127.4 miles (205.1 km), with a travel time of about 02h 24m by car.
- The straight-line flight distance is about 99.7 miles (160.4 km).
- For a round trip, plan for roughly 04h 48m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 24m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Monroe County, Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Knowlton and La Crosse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Knowlton and La Crosse.
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1
Start on Knowlton Road
27 m · 6 sec · Knowlton Road
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2
Continue on Seagull Drive
1.4 km · 2 min · Seagull Drive
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3
Turn left onto State Highway 34
8.4 mi · 12 min · State Highway 34
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4
Take the ramp right
1266 ft · 31 sec
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5
Merge slight left onto US Highway 10
3.8 mi · 4 min · US Highway 10
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6
Take the exit slight right toward WI 34 West, WI 13 South: Wisconsin Rapids
1767 ft · 49 sec
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7
Turn left onto Victory Road
15.2 mi · 22 min · Victory Road
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8
Turn right onto 2nd Avenue South
2831 ft · 1 min · 2nd Avenue South
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9
Enter the roundabout and take exit 3 toward 2nd Avenue South
57 m · 3 sec · 2nd Avenue South
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10
Exit the roundabout onto 2nd Avenue South
1.3 mi · 2 min · 2nd Avenue South
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11
Continue on Wisconsin River Drive
1.6 mi · 2 min · Wisconsin River Drive
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12
Turn right onto Letendre Avenue
1.4 mi · 2 min · Letendre Avenue
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13
Continue on State Highway 54
2.1 mi · 3 min · State Highway 54
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14
Turn left onto County Highway G
2 mi · 3 min · County Highway G
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15
Continue on State Highway 173
9.1 mi · 14 min · State Highway 173
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16
At the end of the road, turn left onto State Highway 80
125 m · 7 sec · State Highway 80
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17
Continue on State Highway 173
1.3 mi · 2 min · State Highway 173
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18
Continue on State Highway 173
23.6 mi · 34 min · State Highway 173
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19
Turn right onto State Highway 21
4 mi · 5 min · State Highway 21
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20
Continue on East McCoy Boulevard
1684 ft · 34 sec · East McCoy Boulevard
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21
Continue on State Highway 21
640 ft · 12 sec · State Highway 21
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22
Take the exit straight
1644 ft · 42 sec
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23
Merge slight left
2.8 mi · 3 min
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24
Take the exit slight right toward I 90 West: La Crosse, Albert Lea
1.2 km · 51 sec
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25
Merge slight left
38.1 mi · 41 min
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26
Take the exit slight right toward WI 16: La Crosse, Onalaska
1636 ft · 42 sec
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27
At the end of the road, turn left
4.9 mi · 9 min
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28
Continue on Losey Boulevard North
2575 ft · 2 min · Losey Boulevard North
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29
Turn right onto Main Street
1.1 km · 2 min · Main Street
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30
Turn left onto 16th Street South
1.3 km · 2 min · 16th Street South
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31
Turn right onto Johnson Street
1824 ft · 1 min · Johnson Street
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32
At the end of the road, turn right onto West Avenue South
99 m · 11 sec · West Avenue South
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33
Arrive at your destination
0 m · 1 sec · West Avenue South
Car Route Details
A richer read on the saved driving route between Knowlton and La Crosse.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 90 West
Merge slight left
38.1 mi · 00h 41m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Knowlton and Sunny near La Crosse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Knowlton to La Crosse?
The road trip is about 127.4 miles (205.1 km) and usually takes 02h 24m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Wyeville is a useful midpoint, sitting about 62.8 miles from Knowlton and 64.7 miles from La Crosse.
How much longer is the road route than the straight-line distance?
The direct path is about 99.7 miles (160.4 km), while the road route adds roughly 27.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:42 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $16.97 one way or $33.94 round trip. Estimated CO2 is about 40 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Knowlton and Sunny near La Crosse.
Stop Ideas Near Wyeville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Wyeville.
Tomah
Wisconsin Rapids, WI
Wisconsin Dells
La Crosse
Flight Path Map
This map shows the direct air route between Knowlton and La Crosse. Straight-line distance: 99.66 mi (160.39 km).
#1 Knowlton
Civil town in Marathon County, Wisconsin
| Population | 2,027 |
| Coordinates | 44.7163600, -89.6826200 |
| Altitude | 340 |
| Country | United States |
#2 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
End: West Avenue South (-91.239623, 43.801338)
Estimated Travel Time
Distance: 205 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 14m |
| 40 mph (64.37 km/h) | 03h 11m |
| 50 mph (80.47 km/h) | 02h 32m |
| 60 mph (96.56 km/h) | 02h 07m |
| 70 mph (112.65 km/h) | 01h 49m |
| 80 mph (129 km/h) | 01h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $16.97 | $33.94 |
| Mid-grade | $4.25 | $19.14 | $38.28 |
| Premium | $4.65 | $20.94 | $41.89 |
| Diesel | $5.30 | $23.87 | $47.74 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.