How far is Kirksville, MO from East Independence, MO?
The driving distance from Kirksville, MO to East Independence, MO is about 162.6 miles (261.6 km), with a travel time of about 02h 57m by car.
- The straight-line flight distance is about 121 miles (194.8 km).
- For a round trip, plan for roughly 05h 55m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 57m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Daviess County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Kirksville and East Independence.
Turn-by-Turn Driving Directions
Step-by-step road directions between Kirksville and East Independence.
-
1
Start on North Franklin Street
898 ft · 42 sec · North Franklin Street
-
2
Turn right onto East Illinois Street
92 m · 11 sec · East Illinois Street
-
3
Turn left onto North Marion Street
1004 ft · 43 sec · North Marion Street
-
4
Continue on North Marion Street
66 m · 9 sec · North Marion Street
-
5
Continue on North Green Street
3195 ft · 1 min · North Green Street
-
6
Turn left onto North Baltimore Street
104 m · 13 sec · North Baltimore Street
-
7
Turn left onto West Potter Avenue
1.1 mi · 2 min · West Potter Avenue
-
8
Continue on Potter Trail
1.6 mi · 3 min · Potter Trail
-
9
Turn left
33.8 mi · 50 min
-
10
Turn right
26.9 mi · 40 min
-
11
Turn left onto Main Street
29.4 mi · 38 min · Main Street
-
12
Continue on 2nd Street
1.5 mi · 2 min · 2nd Street
-
13
Turn straight
4.4 mi · 6 min
-
14
Take the ramp left
918 ft · 22 sec
-
15
Merge slight left
40.9 mi · 44 min
-
16
Take the exit slight right
1274 ft · 34 sec
-
17
At the end of the road, turn left onto Plattsburg Road
552 ft · 11 sec · Plattsburg Road
-
18
Continue on Lightborne Road
820 ft · 16 sec · Lightborne Road
-
19
Continue on Lightburne Street
2.7 mi · 5 min · Lightburne Street
-
20
Continue on South Leonard Street
1 km · 2 min · South Leonard Street
-
21
Take the ramp left
45 m · 3 sec
-
22
Merge slight right
10 mi · 14 min
-
23
Take the exit slight right toward East Truman Road
1709 ft · 52 sec
-
24
Turn left onto East Truman Road
1.4 mi · 3 min · East Truman Road
-
25
Turn left onto Main Road
1341 ft · 1 min · Main Road
-
26
Turn right onto East 9th Street South
24 m · 3 sec · East 9th Street South
-
27
Arrive at your destination
0 m · 1 sec · East 9th Street South
Car Route Details
A richer read on the saved driving route between Kirksville and East Independence.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
2nd Street
Merge slight left
40.9 mi · 00h 44m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Kirksville and Mostly Sunny near East Independence.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Kirksville to East Independence?
The road trip is about 162.6 miles (261.6 km) and usually takes 02h 57m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Jamesport is a useful midpoint, sitting about 78.4 miles from Kirksville and 84.2 miles from East Independence.
How much longer is the road route than the straight-line distance?
The direct path is about 121 miles (194.8 km), while the road route adds roughly 41.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 12:34 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $21.65 one way or $43.29 round trip. Estimated CO2 is about 51 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Kirksville and Mostly Sunny near East Independence.
Stop Ideas Near Jamesport
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Jamesport.
Independence
La Plata
Osceola
Union Station
Flight Path Map
This map shows the direct air route between Kirksville and East Independence. Straight-line distance: 121.06 mi (194.82 km).
#1 Kirksville
City in Adair County, Missouri, United States
| Population | 17,653 |
| Coordinates | 40.1947500, -92.5832500 |
| Altitude | 299 |
| Country | United States |
#2 East Independence
A census-designated place in Jackson County, Missouri.
| Population | 110,675 |
| Coordinates | 39.0955600, -94.3552300 |
| Altitude | 256 |
| Country | United States |
End: East 9th Street South (-94.355237, 39.09539)
Estimated Travel Time
Distance: 262 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 24m |
| 40 mph (64.37 km/h) | 04h 03m |
| 50 mph (80.47 km/h) | 03h 15m |
| 60 mph (96.56 km/h) | 02h 42m |
| 70 mph (112.65 km/h) | 02h 19m |
| 80 mph (129 km/h) | 02h 01m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $21.65 | $43.29 |
| Mid-grade | $4.25 | $24.41 | $48.82 |
| Premium | $4.65 | $26.71 | $53.43 |
| Diesel | $5.30 | $30.44 | $60.89 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Jun 03, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.