How far is Keystone, FL from Gainesville, FL?
The driving distance from Keystone, FL to Gainesville, FL is about 136.7 miles (220 km), with a travel time of about 02h 22m by car.
- The straight-line flight distance is about 104.9 miles (168.8 km).
- For a round trip, plan for roughly 04h 44m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 22m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Sumter County, Florida
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Keystone and Gainesville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Keystone and Gainesville.
-
1
Start on Blue Tick Road
1234 ft · 60 sec · Blue Tick Road
-
2
Turn left onto Brooker Creek Drive
1302 ft · 57 sec · Brooker Creek Drive
-
3
Continue on Tyler Run Avenue
1.2 km · 2 min · Tyler Run Avenue
-
4
At the end of the road, turn left onto Tyler Road
1.1 km · 2 min · Tyler Road
-
5
At the end of the road, turn left onto Tarpon Springs Road
3.9 mi · 7 min · Tarpon Springs Road
-
6
At the end of the road, turn left onto Gunn Highway
3113 ft · 1 min · Gunn Highway
-
7
Turn right onto Lutz Lake Fern Road
6.1 mi · 11 min · Lutz Lake Fern Road
-
8
Turn left onto North Dale Mabry Highway
2.2 mi · 3 min · North Dale Mabry Highway
-
9
Turn straight onto Land O' Lakes Boulevard
1797 ft · 31 sec · Land O' Lakes Boulevard
-
10
Turn right onto State Road 54
4.4 mi · 7 min · State Road 54
-
11
Continue on State Road 56
2366 ft · 39 sec · State Road 56
-
12
Continue straight
2556 ft · 42 sec
-
13
Take the ramp slight left toward I 75 North: Ocala
2546 ft · 1 min
-
14
Merge slight left
97.7 mi · 1 hr 45 min
-
15
Take the exit slight right toward CR 234: Micanopy
1213 ft · 32 sec
-
16
Turn right onto Southeast County Road 234
1.3 mi · 2 min · Southeast County Road 234
-
17
Turn left
128 m · 15 sec
-
18
Turn straight
8 mi · 10 min
-
19
Turn right onto Southwest Williston Road
2889 ft · 1 min · Southwest Williston Road
-
20
Turn left onto South Main Street
1.6 mi · 3 min · South Main Street
-
21
Enter the roundabout and take exit 2 toward South Main Street
28 m · 2 sec · South Main Street
-
22
Exit the roundabout onto South Main Street
1317 ft · 32 sec · South Main Street
-
23
Enter the roundabout and take exit 2 toward South Main Street
54 m · 4 sec · South Main Street
-
24
Exit the roundabout onto South Main Street
2512 ft · 1 min · South Main Street
-
25
Arrive at your destination
0 m · 1 sec · South Main Street
Car Route Details
A richer read on the saved driving route between Keystone and Gainesville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 75 North
Merge slight left
97.7 mi · 01h 45m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving Keystone and Mostly Sunny near Gainesville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Keystone to Gainesville?
The road trip is about 136.7 miles (220 km) and usually takes 02h 22m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Lake Panasoffkee is a useful midpoint, sitting about 65.7 miles from Keystone and 71 miles from Gainesville.
How much longer is the road route than the straight-line distance?
The direct path is about 104.9 miles (168.8 km), while the road route adds roughly 31.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 1:46 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $19.99 one way or $39.99 round trip. Estimated CO2 is about 42.8 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Keystone and Mostly Sunny near Gainesville.
Stop Ideas Near Lake Panasoffkee
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lake Panasoffkee.
Wildwood, Florida
The Villages-Lady Lake, FL
Dade City, Florida
Ocala, Florida
Flight Path Map
This map shows the direct air route between Keystone and Gainesville. Straight-line distance: 104.89 mi (168.81 km).
#1 Keystone
Census-designated place in Hillsborough County, Florida
| Population | 24,039 |
| Coordinates | 28.1558500, -82.6212100 |
| Altitude | 12 |
| Country | United States |
#2 Gainesville
The third most populous city in Florida.
| Population | 135,004 |
| Coordinates | 29.6516300, -82.3248300 |
| Altitude | 54 |
| Country | United States |
End: South Main Street (-82.32501, 29.65163)
Estimated Travel Time
Distance: 220 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 04h 33m |
| 40 mph (64.37 km/h) | 03h 25m |
| 50 mph (80.47 km/h) | 02h 44m |
| 60 mph (96.56 km/h) | 02h 16m |
| 70 mph (112.65 km/h) | 01h 57m |
| 80 mph (129 km/h) | 01h 42m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $19.99 | $39.99 |
| Mid-grade | $4.60 | $22.15 | $44.31 |
| Premium | $4.90 | $23.60 | $47.20 |
| Diesel | $4.35 | $20.97 | $41.93 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.