How far is Hendry County, FL from Gainesville, FL?
The driving distance from Hendry County, FL to Gainesville, FL is about 274.7 miles (442.1 km), with a travel time of about 07h 17m by car.
- The straight-line flight distance is about 225.4 miles (362.8 km).
- For a round trip, plan for roughly 14h 34m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 17m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Polk County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Cloudy
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Hendry County and Gainesville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Hendry County and Gainesville.
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1
Start on Sam Jones Trail
3.7 mi · 6 min · Sam Jones Trail
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2
Continue on South Devil's Garden Road
3.9 mi · 7 min · South Devil's Garden Road
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3
Continue on Sam Jones Trail
6.1 mi · 10 min · Sam Jones Trail
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4
Turn right
2.7 mi · 4 min
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5
Keep slight left to continue on US 27 North: Sebring
1687 ft · 39 sec
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6
Turn left onto FL 80 West: La Belle, Fort Myers
3040 ft · 1 min
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7
Merge slight left
47.9 mi · 59 min
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8
Continue straight
918 ft · 20 sec
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9
Continue straight
10.1 mi · 13 min
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10
Continue straight
41.5 mi · 55 min
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11
Continue straight
27.8 mi · 39 min
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12
Continue straight
13.7 mi · 19 min
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13
Continue straight
10.1 mi · 15 min
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14
Continue straight
1507 ft · 23 sec
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15
Keep slight right
3 mi · 4 min
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16
Take the exit slight left toward Florida's Turnpike North: Ocala
883 ft · 23 sec
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17
Continue on Florida's Turnpike North: Ocala
1991 ft · 49 sec
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18
Merge slight left onto Florida's Turnpike
18.9 mi · 20 min · Florida's Turnpike
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19
Keep slight left to continue on Florida's Turnpike
1281 ft · 16 sec · Florida's Turnpike
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20
Merge slight left
46.1 mi · 49 min
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21
Take the exit slight right toward CR 234: Micanopy
1213 ft · 32 sec
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22
Turn right onto Southeast County Road 234
1.3 mi · 2 min · Southeast County Road 234
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23
Turn left
128 m · 15 sec
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24
Turn straight
8 mi · 10 min
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25
Turn right onto Southwest Williston Road
2889 ft · 1 min · Southwest Williston Road
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26
Turn left onto South Main Street
1.6 mi · 3 min · South Main Street
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27
Enter the roundabout and take exit 2 toward South Main Street
28 m · 2 sec · South Main Street
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28
Exit the roundabout onto South Main Street
1317 ft · 32 sec · South Main Street
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29
Enter the roundabout and take exit 2 toward South Main Street
54 m · 4 sec · South Main Street
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30
Exit the roundabout onto South Main Street
2512 ft · 1 min · South Main Street
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31
Arrive at your destination
0 m · 1 sec · South Main Street
Car Route Details
A richer read on the saved driving route between Hendry County and Gainesville.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
FL 80 West
Merge slight left
47.9 mi · 00h 59m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Partly Cloudy leaving Hendry County and Chance Showers And Thunderstorms near Gainesville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Hendry County to Gainesville?
The road trip is about 274.7 miles (442.1 km) and usually takes 07h 17m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Lake Hamilton is a useful midpoint, sitting about 125.5 miles from Hendry County and 149.3 miles from Gainesville.
How much longer is the road route than the straight-line distance?
The direct path is about 225.4 miles (362.8 km), while the road route adds roughly 49.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.19 one way or $80.39 round trip. Estimated CO2 is about 86.1 kg one way.
What should you check before leaving?
Before you leave, expect Partly Cloudy around Hendry County and Chance Showers And Thunderstorms near Gainesville.
Stop Ideas Near Lake Hamilton
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lake Hamilton.
Winter Haven
Lakeland
Lakeland
Kissimmee
Flight Path Map
This map shows the direct air route between Hendry County and Gainesville. Straight-line distance: 225.41 mi (362.76 km).
#1 Hendry County
County in Florida, United States of America
| Population | 42,813 |
| Coordinates | 26.5534900, -81.1659000 |
| Altitude | 9 |
| Country | United States |
#2 Gainesville
The third most populous city in Florida.
| Population | 135,004 |
| Coordinates | 29.6516300, -82.3248300 |
| Altitude | 54 |
| Country | United States |
End: South Main Street (-82.32501, 29.65163)
Estimated Travel Time
Distance: 442 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 09m |
| 40 mph (64.37 km/h) | 06h 52m |
| 50 mph (80.47 km/h) | 05h 29m |
| 60 mph (96.56 km/h) | 04h 34m |
| 70 mph (112.65 km/h) | 03h 55m |
| 80 mph (129 km/h) | 03h 25m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $40.19 | $80.39 |
| Mid-grade | $4.60 | $44.54 | $89.07 |
| Premium | $4.90 | $47.44 | $94.88 |
| Diesel | $4.35 | $42.15 | $84.30 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Jul 27, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.