How far is Henderson, TX from San Antonio, TX?
The driving distance from Henderson, TX to San Antonio, TX is about 334.2 miles (537.9 km), with a travel time of about 05h 31m by car.
- The straight-line flight distance is about 289.2 miles (465.4 km).
- For a round trip, plan for roughly 11h 03m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 31m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Milam County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Showers And Thunderstorms
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Henderson and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Henderson and San Antonio.
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1
Start on East Main Street
14 m · 3 sec · East Main Street
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2
Turn left onto South Main Street
1.2 km · 1 min · South Main Street
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3
Turn right onto Jacksonville Drive
1.6 km · 2 min · Jacksonville Drive
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4
At the end of the road, turn right onto Highway 79
27.9 mi · 41 min · Highway 79
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5
Continue on East Rusk Street
4.1 mi · 6 min · East Rusk Street
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6
Continue on US Highway 79 West
22.9 mi · 26 min · US Highway 79 West
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7
Continue on East Palestine Avenue
3.5 mi · 5 min · East Palestine Avenue
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8
Continue on West Oak Street
11.7 mi · 14 min · West Oak Street
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9
Turn straight
74.8 mi · 1 hr 25 min
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10
Take the exit slight right
1.5 km · 1 min
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11
Continue straight
53.9 mi · 1 hr 7 min
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12
Turn left onto Porter Street
716 ft · 23 sec · Porter Street
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13
Turn right onto East 2nd Street
6.9 mi · 9 min · East 2nd Street
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14
Continue straight
2.6 mi · 4 min
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15
Turn left onto Chris Kelley Boulevard
2.1 mi · 3 min · Chris Kelley Boulevard
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16
Turn left onto TX 130 Frontage Road
1.3 mi · 2 min · TX 130 Frontage Road
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17
Take the ramp slight left toward TX 130 Toll South: Austin, Pflugerville
926 ft · 11 sec
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18
Continue on Toll 130 South: Austin, Pflugerville
1360 ft · 15 sec
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19
Merge slight left onto Pickle Parkway
70.3 mi · 1 hr 4 min · Pickle Parkway
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20
Keep slight right to continue on I 10 West: San Antonio
3262 ft · 1 min
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21
Merge slight left
11.1 mi · 11 min
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22
Continue straight
9.4 mi · 9 min
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23
Keep slight left
12 mi · 13 min
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24
Keep slight left to continue on 90th Infantry Division Highway
1.2 km · 52 sec · 90th Infantry Division Highway
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25
Continue on Jose Lopez Freeway
1.6 mi · 2 min · Jose Lopez Freeway
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26
Take the exit slight right toward Commerce Street, Houston Street
790 ft · 19 sec
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27
Turn straight onto Interstate 10 East
1830 ft · 39 sec · Interstate 10 East
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28
Turn right onto East Houston Street
963 ft · 20 sec · East Houston Street
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29
Turn slight left onto East Commerce Street
4.3 mi · 7 min · East Commerce Street
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30
Turn left onto Military Plaza
119 m · 16 sec · Military Plaza
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31
Turn left onto Dolorosa Street
100 m · 8 sec · Dolorosa Street
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32
Arrive at your destination
0 m · 1 sec · Dolorosa Street
Car Route Details
A richer read on the saved driving route between Henderson and San Antonio.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Longest stretch
Turn straight
74.8 mi · 01h 25m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms then Showers And Thunderstorms leaving Henderson and Showers And Thunderstorms near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Henderson to San Antonio?
The road trip is about 334.2 miles (537.9 km) and usually takes 05h 31m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Milano is a useful midpoint, sitting about 162.9 miles from Henderson and 171.4 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 289.2 miles (465.4 km), while the road route adds roughly 45 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 5:56 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $44.59 one way or $89.18 round trip. Estimated CO2 is about 104.9 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms then Showers And Thunderstorms around Henderson and Showers And Thunderstorms near San Antonio.
Stop Ideas Near Milano
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Milano.
Bryan, TX
Taylor
Temple
Killeen, Texas
Flight Path Map
This map shows the direct air route between Henderson and San Antonio. Straight-line distance: 289.16 mi (465.36 km).
#1 Henderson
City in Rusk County, Texas, United States
| Population | 13,049 |
| Coordinates | 32.1532200, -94.7993800 |
| Altitude | 156 |
| Country | United States |
#2 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
End: Dolorosa Street (-98.493645, 29.424163)
Estimated Travel Time
Distance: 538 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 08m |
| 40 mph (64.37 km/h) | 08h 21m |
| 50 mph (80.47 km/h) | 06h 41m |
| 60 mph (96.56 km/h) | 05h 34m |
| 70 mph (112.65 km/h) | 04h 46m |
| 80 mph (129 km/h) | 04h 10m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $44.59 | $89.18 |
| Mid-grade | $4.25 | $50.17 | $100.35 |
| Premium | $4.59 | $54.17 | $108.35 |
| Diesel | $3.99 | $47.12 | $94.23 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · May 27, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.