How far is Guthrie, KY from Florence, KY?
The driving distance from Guthrie, KY to Florence, KY is about 254.3 miles (409.3 km), with a travel time of about 04h 03m by car.
- The straight-line flight distance is about 213.5 miles (343.6 km).
- For a round trip, plan for roughly 08h 06m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 03m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat of Hardin County, Kentucky, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Guthrie and Florence.
Turn-by-Turn Driving Directions
Step-by-step road directions between Guthrie and Florence.
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1
Start on Ewing Street
1.4 km · 1 min · Ewing Street
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2
At the end of the road, turn right onto Russellville Road
8.9 mi · 13 min · Russellville Road
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3
Continue on Clarksville Road
10.6 mi · 16 min · Clarksville Road
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4
Continue on West 9th Street
696 ft · 14 sec · West 9th Street
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5
Continue on Clarksville Road
2353 ft · 42 sec · Clarksville Road
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6
Continue on West 9th Street
1.8 mi · 3 min · West 9th Street
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7
At the end of the road, turn right onto Bowling Green Road
2964 ft · 52 sec · Bowling Green Road
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8
Continue on East Jefferson Davis Highway
3.2 mi · 4 min · East Jefferson Davis Highway
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9
Continue on Bowling Green Road
11.8 mi · 13 min · Bowling Green Road
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10
Continue on Russellville Road
8 mi · 9 min · Russellville Road
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11
Take the exit slight right toward I 165 South
1676 ft · 41 sec
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12
Merge slight left
4.8 mi · 5 min
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13
Take the exit slight right toward I 65 North: Louisville
1997 ft · 59 sec
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14
Keep slight left to continue on I 65 North: Louisville
1.1 km · 54 sec
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15
Merge slight left onto Interstate Highway 65
108.4 mi · 1 hr 57 min · Interstate Highway 65
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16
Take the exit slight right toward I 264: Watterson Expressway, Airport
1.1 km · 59 sec
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17
Keep slight right to continue on I 264 East: Watterson Expressway
1.3 km · 1 min
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18
Merge slight left onto Henry Watterson Expressway
10 mi · 14 min · Henry Watterson Expressway
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19
Keep slight right to continue on I 71 North: Cincinnati
1877 ft · 32 sec
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20
Merge slight left
71 mi · 1 hr 17 min
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21
Keep slight left to continue on I 75 North, I 71 North: Cincinnati
7.8 mi · 8 min
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22
Take the exit slight right toward US 42, US 127: Union, Florence
1817 ft · 47 sec
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23
Turn right
74 m · 4 sec
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24
Continue straight
1.1 mi · 2 min
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25
Turn left onto Main Street
8 m · 1 sec · Main Street
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26
Arrive at your destination
0 m · 1 sec · Main Street
Car Route Details
A richer read on the saved driving route between Guthrie and Florence.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Interstate Highway 65
Merge slight left onto Interstate Highway 65
108 mi · 01h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms leaving Guthrie and Showers And Thunderstorms near Florence.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Guthrie to Florence?
The road trip is about 254.3 miles (409.3 km) and usually takes 04h 03m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Elizabethtown is a useful midpoint, sitting about 126.4 miles from Guthrie and 127.9 miles from Florence.
How much longer is the road route than the straight-line distance?
The direct path is about 213.5 miles (343.6 km), while the road route adds roughly 40.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:54 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $33.83 one way or $67.65 round trip. Estimated CO2 is about 79.7 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Guthrie and Florence, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Guthrie and Showers And Thunderstorms near Florence.
Stop Ideas Near Elizabethtown
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Elizabethtown.
Louisville, Kentucky
Flight Path Map
This map shows the direct air route between Guthrie and Florence. Straight-line distance: 213.5 mi (343.59 km).
#1 Guthrie
City in Kentucky, USA
| Population | 1,426 |
| Coordinates | 36.6483800, -87.1663900 |
| Altitude | 167 |
| Country | United States |
#2 Florence
City in Kentucky, US
| Population | 33,423 |
| Coordinates | 38.9989500, -84.6266100 |
| Altitude | 282 |
| Country | United States |
End: Main Street (-84.626623, 38.998947)
Estimated Travel Time
Distance: 409 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 28m |
| 40 mph (64.37 km/h) | 06h 21m |
| 50 mph (80.47 km/h) | 05h 05m |
| 60 mph (96.56 km/h) | 04h 14m |
| 70 mph (112.65 km/h) | 03h 38m |
| 80 mph (129 km/h) | 03h 10m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $33.83 | $67.65 |
| Mid-grade | $4.25 | $38.15 | $76.30 |
| Premium | $4.65 | $41.75 | $83.49 |
| Diesel | $5.30 | $47.58 | $95.15 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Kentucky · Apr 29, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.