How far is Florence, KY from Guthrie, KY?
The driving distance from Florence, KY to Guthrie, KY is about 253.3 miles (407.6 km), with a travel time of about 04h 51m by car.
- The straight-line flight distance is about 213.5 miles (343.6 km).
- For a round trip, plan for roughly 09h 42m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 51m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat of Hardin County, Kentucky, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Florence and Guthrie.
Turn-by-Turn Driving Directions
Step-by-step road directions between Florence and Guthrie.
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1
Start on Main Street
8 m · 3 sec · Main Street
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2
Turn right
1.1 mi · 2 min
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3
Continue straight
1288 ft · 27 sec
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4
Turn left onto I 71 South, I 75 South: Lexington, Louisville
2100 ft · 53 sec
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5
Merge slight left
6.9 mi · 7 min
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6
Take the exit slight right toward I 71 South: Louisville
71.5 mi · 1 hr 18 min
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7
Take the exit slight left toward I 264 West: Watterson Expressway
2346 ft · 45 sec
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8
Continue on Henry Watterson Expressway
10 mi · 14 min · Henry Watterson Expressway
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9
Take the exit slight right toward I 65, KY 61: Nashville, Indianapolis
936 ft · 15 sec
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10
Keep slight left to continue on I 65: Nashville, Downtown Louisville, Indianapolis
963 ft · 15 sec
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11
Keep slight left to continue on I 65 South: Nashville
1 mi · 2 min
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12
Merge slight left
109.4 mi · 1 hr 58 min
-
13
Take the exit slight right toward I 165, KY 9007: Owensboro, Scottsville
1272 ft · 22 sec
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14
Keep slight right to continue on I 165: Owensboro
2931 ft · 50 sec
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15
Merge slight left
4.3 mi · 5 min
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16
Take the exit slight right toward US 68, KY 80: Russellville, Bowling Green
1843 ft · 45 sec
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17
Turn left onto Russellville Road
8.2 mi · 10 min · Russellville Road
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18
Continue on Bowling Green Road
11.8 mi · 13 min · Bowling Green Road
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19
Continue on East Jefferson Davis Highway
3.2 mi · 4 min · East Jefferson Davis Highway
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20
Continue on Bowling Green Road
2964 ft · 54 sec · Bowling Green Road
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21
Turn left onto East 9th Street
1.8 mi · 3 min · East 9th Street
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22
Continue on Clarksville Road
2287 ft · 41 sec · Clarksville Road
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23
Continue on West 9th Street
762 ft · 15 sec · West 9th Street
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24
Continue on Clarksville Road
10.6 mi · 16 min · Clarksville Road
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25
Continue on Russellville Road
8.9 mi · 13 min · Russellville Road
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26
Turn left onto Ewing Street
1.4 km · 1 min · Ewing Street
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27
Arrive at your destination
0 m · 1 sec · Ewing Street
Car Route Details
A richer read on the saved driving route between Florence and Guthrie.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 65 South
Merge slight left
109 mi · 01h 58m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms leaving Florence and Chance Showers And Thunderstorms near Guthrie.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Florence to Guthrie?
The road trip is about 253.3 miles (407.6 km) and usually takes 04h 51m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Elizabethtown is a useful midpoint, sitting about 126.6 miles from Florence and 126.6 miles from Guthrie.
How much longer is the road route than the straight-line distance?
The direct path is about 213.5 miles (343.6 km), while the road route adds roughly 39.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:18 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $33.71 one way or $67.43 round trip. Estimated CO2 is about 79.4 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Florence and Guthrie, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms around Florence and Chance Showers And Thunderstorms near Guthrie.
Stop Ideas Near Elizabethtown
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Elizabethtown.
Louisville, Kentucky
Flight Path Map
This map shows the direct air route between Florence and Guthrie. Straight-line distance: 213.5 mi (343.59 km).
#1 Florence
City in Kentucky, US
| Population | 33,423 |
| Coordinates | 38.9989500, -84.6266100 |
| Altitude | 282 |
| Country | United States |
#2 Guthrie
City in Kentucky, USA
| Population | 1,426 |
| Coordinates | 36.6483800, -87.1663900 |
| Altitude | 167 |
| Country | United States |
End: Guthrie (-87.16639, 36.64838)
Estimated Travel Time
Distance: 408 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 26m |
| 40 mph (64.37 km/h) | 06h 19m |
| 50 mph (80.47 km/h) | 05h 03m |
| 60 mph (96.56 km/h) | 04h 13m |
| 70 mph (112.65 km/h) | 03h 37m |
| 80 mph (129 km/h) | 03h 09m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $33.71 | $67.43 |
| Mid-grade | $4.25 | $38.02 | $76.04 |
| Premium | $4.65 | $41.61 | $83.21 |
| Diesel | $5.30 | $47.42 | $94.84 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Kentucky · Apr 29, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.