How far is Guilford, IN from Saint John, IN?
The driving distance from Guilford, IN to Saint John, IN is about 218.9 miles (352.3 km), with a travel time of about 03h 27m by car.
- The straight-line flight distance is about 156.3 miles (251.5 km).
- For a round trip, plan for roughly 06h 55m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 27m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Indiana, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Partly Cloudy
Driving Route Map
The map below follows the saved road route between Guilford and Saint John.
Turn-by-Turn Driving Directions
Step-by-step road directions between Guilford and Saint John.
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1
Start on the route
43 m · 8 sec
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2
Turn right onto Main Street
1346 ft · 47 sec · Main Street
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3
At the end of the road, turn right onto SR 1
5.1 mi · 9 min · SR 1
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4
Continue on Oberting Road
1854 ft · 51 sec · Oberting Road
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5
Turn left
37 m · 36 sec
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6
Continue straight
37 m · 11 sec
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7
Turn right onto Oberting Road
1854 ft · 53 sec · Oberting Road
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8
Turn left
117 m · 14 sec
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9
Turn left onto Belleview Drive
1816 ft · 44 sec · Belleview Drive
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10
Continue on I 275: Ohio, Kentucky
2193 ft · 56 sec
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11
Keep slight right to continue on I 275 South: Kentucky
2645 ft · 1 min
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12
Merge slight left onto Cincinnati Bypass
1.1 mi · 1 min · Cincinnati Bypass
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13
Continue on Ronald Reagan Highway
13.1 mi · 15 min · Ronald Reagan Highway
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14
Take the exit slight right toward I 71, I 75: Cincinnati, Lexington, Louisville
1476 ft · 36 sec
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15
Keep slight right to continue on I 71 South, I 75 South: Lexington, Louisville
1.1 km · 1 min
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16
Keep slight left to continue on I 71 South, I 75 South, KY 236 East: Lexington, Louisville, Erlanger
1973 ft · 48 sec
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17
Keep slight left to continue on I 71 South, I 75 South: Lexington, Louisville
1.1 km · 1 min
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18
Merge slight left
10.3 mi · 11 min
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19
Take the exit slight right toward I 71 South: Louisville
67.4 mi · 1 hr 13 min
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20
Take the exit slight right toward KY 841 North
736 ft · 18 sec
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21
Keep slight right to continue on KY 841 North
2995 ft · 1 min
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22
Merge slight left onto Gene Snyder Freeway
3 mi · 3 min · Gene Snyder Freeway
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23
Continue on Lewis and Clark Bridge
6.1 mi · 7 min · Lewis and Clark Bridge
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24
Continue straight
1.3 km · 58 sec
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25
Continue straight
6.4 mi · 7 min
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26
Continue on I 64 West, SR 62 West: Saint Louis
2548 ft · 54 sec
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27
Merge slight left
1.7 mi · 2 min
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28
Continue straight
90.4 mi · 1 hr 38 min
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29
Take the exit slight right toward I 69 South, SR 57 South: Evansville, Henderson, Kentucky
1463 ft · 50 sec
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30
Merge slight left
5.3 mi · 6 min
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31
Take the exit slight right toward Boonville-New Harmony Road
1764 ft · 43 sec
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32
Turn left onto East Boonville New Harmony Road
1532 ft · 42 sec · East Boonville New Harmony Road
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33
Continue on New Harmony Road
1.4 mi · 3 min · New Harmony Road
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34
Turn right onto St John Road
1.1 mi · 4 min · St John Road
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35
Arrive at your destination
0 m · 1 sec · St John Road
Car Route Details
A richer read on the saved driving route between Guilford and Saint John.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 64 West
Continue straight
90.4 mi · 01h 38m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms leaving Guilford and Partly Cloudy near Saint John.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Guilford to Saint John?
The road trip is about 218.9 miles (352.3 km) and usually takes 03h 27m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Utica is a useful midpoint, sitting about 109.7 miles from Guilford and 109.2 miles from Saint John.
How much longer is the road route than the straight-line distance?
The direct path is about 156.3 miles (251.5 km), while the road route adds roughly 62.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 10:04 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $29.11 one way or $58.22 round trip. Estimated CO2 is about 68.6 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Guilford and Saint John, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Guilford and Partly Cloudy near Saint John.
Stop Ideas Near Utica
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Utica.
Louisville, Kentucky
Flight Path Map
This map shows the direct air route between Guilford and Saint John. Straight-line distance: 156.29 mi (251.53 km).
#1 Guilford
Unincorporated community in Indiana
| Population | 35,285 |
| Coordinates | 39.1681100, -84.9119000 |
| Altitude | 152 |
| Country | United States |
#2 Saint John
Town in Indiana, United States
| Population | 19,616 |
| Coordinates | 38.0792100, -87.4500100 |
| Altitude | 131 |
| Country | United States |
End: St John Road (-87.44975, 38.079207)
Estimated Travel Time
Distance: 352 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 17m |
| 40 mph (64.37 km/h) | 05h 28m |
| 50 mph (80.47 km/h) | 04h 22m |
| 60 mph (96.56 km/h) | 03h 38m |
| 70 mph (112.65 km/h) | 03h 07m |
| 80 mph (129 km/h) | 02h 43m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $29.11 | $58.22 |
| Mid-grade | $4.25 | $32.83 | $65.67 |
| Premium | $4.65 | $35.93 | $71.86 |
| Diesel | $5.30 | $40.95 | $81.89 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Indiana · Apr 15, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.