How far is Greer, SC from Myrtle Beach, SC?
Fastest route
The distance from Greer, South Carolina to Myrtle Beach, South Carolina is approximately 256 miles (412 kilometers). The fastest route, considering traffic conditions, is via I-20 E. Here are some tips and suggestions for the journey:
Directions
- 🚗 Take I-85 S: Head northwest on E Poinsett St toward S Main St. Turn left at the 1st cross street onto SC-14 E/S Main St. Continue to follow SC-14 E. Use the right lane to merge onto I-85 S via the ramp to Greenville.
- 🛣️ Follow I-385 S and I-26 E: Keep following I-85 S until you reach I-385 S. Use the right 3 lanes to take exit 51 for I-385 S toward Columbia/Greenville. Keep left and merge onto I-385 S. Stay left at the fork to continue on I-385 S.
- 🛣️ Take I-20 E: Take exit 107B to merge onto I-20 E toward Florence. Use the left 2 lanes to take exit 141A to merge onto I-95 N toward Fayetteville. Take exit 170 to merge onto SC-327 S.
- 🚗 Continue on SC-327 S: Follow State Rd S-21-24, US-76 E, S Hwy 501 S, and US-501 S. Slight left toward State Rd S-21-24, then turn left at the 1st cross street onto State Rd S-21-24. Use any lane to turn left onto US-301 N/US-76 E. Keep right to continue on US-76 E and merge onto SC-41 ALT S/S Hwy 501 S.
- 🛣️ Stay on US-501 S: Continue following S Hwy 501 S until you reach US-501 S. Keep straight to stay on US-501 S. Pass by Hardee's (on the right in 15.5 mi) and continue straight onto US-501 S. Pass by Pizza Inn (on the left in 9.1 mi).
- 🚗 Take US-17 BUS N: Keep right to stay on US-501 S and then take a slight right onto 3rd Ave S. Turn left onto US-17 BUS N. Pass by Krispy Kreme (on the left) until you reach Myrtle Beach, South Carolina.
Tips & Suggestions
- 🚗 Plan for a road trip playlist to enjoy during the journey.
- ⛽ Make sure to fill up your gas tank before hitting the road.
- 📞 Have emergency contact numbers handy in case of any unforeseen situations.
- 🚧 Stay updated on traffic conditions and consider using a navigation app for real-time updates.
- 🍴 Pack some snacks and drinks for the trip to stay energized.
- 🧴 Don't forget to bring hand sanitizer and wipes for hygiene purposes.
- 📷 Take breaks along the way to capture scenic views or stretch your legs.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 08m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Kershaw County, South Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Greer and Myrtle Beach.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greer and Myrtle Beach.
-
1
Start on East Poinsett Street
4.3 mi · 7 min · East Poinsett Street
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2
Continue on West Main Street
2078 ft · 51 sec · West Main Street
-
3
Keep slight right to continue on West Main Street
5.9 mi · 12 min · West Main Street
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4
Continue on Moore Duncan Highway
6.2 mi · 10 min · Moore Duncan Highway
-
5
Turn left onto Highway 221
1.3 km · 1 min · Highway 221
-
6
Take the ramp right
797 ft · 19 sec
-
7
Merge slight left
78.8 mi · 1 hr 26 min
-
8
Take the exit slight right toward I 20 East: Florence
1687 ft · 41 sec
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9
Merge slight left
79.3 mi · 1 hr 30 min
-
10
Turn left onto West Evans Street
2.4 mi · 5 min · West Evans Street
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11
Turn right onto Warley Street
644 ft · 20 sec · Warley Street
-
12
Turn left onto West Cheves Street
1.7 mi · 3 min · West Cheves Street
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13
At the end of the road, turn left onto East Palmetto Street
18.9 mi · 25 min · East Palmetto Street
-
14
Continue straight
3.1 mi · 4 min
-
15
Continue straight
41.9 mi · 55 min
-
16
Turn straight
2 mi · 4 min
-
17
Turn slight right onto 8th Avenue North
76 m · 15 sec · 8th Avenue North
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18
Turn right onto North Kings Highway
1443 ft · 41 sec · North Kings Highway
-
19
Turn left onto 5th Avenue North
61 m · 11 sec · 5th Avenue North
-
20
Turn right
60 m · 14 sec
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21
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Greer and Myrtle Beach.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 20 East
Merge slight left
79.3 mi · 01h 30m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Greer and Sunny near Myrtle Beach.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greer to Myrtle Beach?
The road trip is about 257.4 miles (414.2 km) and usually takes 04h 08m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Lugoff is a useful midpoint, sitting about 123.2 miles from Greer and 134.2 miles from Myrtle Beach.
How much longer is the road route than the straight-line distance?
The direct path is about 209.3 miles (336.8 km), while the road route adds roughly 48.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:42 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.97 one way or $71.93 round trip. Estimated CO2 is about 80.7 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Greer and Sunny near Myrtle Beach.
Stop Ideas Near Lugoff
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lugoff.
Camden
Columbia
Florence
Kingstree
Flight Path Map
This map shows the direct air route between Greer and Myrtle Beach. Straight-line distance: 209.26 mi (336.77 km).
#1 Greer
City between Greenville and Spartanburg counties in the US state of South Carolina
| Population | 35,316 |
| Coordinates | 34.9387300, -82.2270600 |
| Altitude | 312 |
| Country | United States |
#2 Myrtle Beach
Coastal city in South Carolina, United States
| Population | 35,555 |
| Coordinates | 33.6890600, -78.8866900 |
| Altitude | 8 |
| Country | United States |
End: North Kings Highway (-78.887105, 33.689329)
Estimated Travel Time
Distance: 414 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 34m |
| 40 mph (64.37 km/h) | 06h 26m |
| 50 mph (80.47 km/h) | 05h 08m |
| 60 mph (96.56 km/h) | 04h 17m |
| 70 mph (112.65 km/h) | 03h 40m |
| 80 mph (129 km/h) | 03h 12m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $35.97 | $71.93 |
| Mid-grade | $4.43 | $40.22 | $80.43 |
| Premium | $4.78 | $43.38 | $86.77 |
| Diesel | $5.62 | $51.07 | $102.13 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.