How far is Greenville, TX from San Antonio, TX?
The driving distance from Greenville, TX to San Antonio, TX is about 343.8 miles (553.3 km), with a travel time of about 05h 03m by car.
- The straight-line flight distance is about 292.7 miles (471 km).
- For a round trip, plan for roughly 10h 07m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 03m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in McLennan County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny then Chance Showers And Thunderstorms
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Greenville and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and San Antonio.
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1
Start on the route
9 m · 4 sec
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2
Turn right onto Pickett Street
14 m · 4 sec · Pickett Street
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3
Turn right onto King Street
83 m · 10 sec · King Street
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4
Turn right onto Washington Street
1158 ft · 29 sec · Washington Street
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5
Turn right onto Stonewall Street
3018 ft · 1 min · Stonewall Street
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6
Turn left onto Park Street
2763 ft · 49 sec · Park Street
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7
Turn right onto Moulton Street
1.2 km · 1 min · Moulton Street
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8
Turn right onto I-30 Frontage Road
931 ft · 19 sec · I-30 Frontage Road
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9
Take the ramp straight
829 ft · 20 sec
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10
Merge slight left onto Martin Luther King Jr Freeway
48.3 mi · 53 min · Martin Luther King Jr Freeway
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11
Take the exit slight right toward I 35E: Denton, Waco
3065 ft · 1 min
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12
Keep slight left to continue on I 35E South, I 35E North: Waco, Denton
607 ft · 15 sec
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13
Keep slight left to continue on I 35E North, I 35E South: Denton, Waco
67 m · 5 sec
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14
Keep slight left to continue on I 35E South: Waco
1915 ft · 30 sec
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15
Continue on South R L Thornton Freeway
2866 ft · 44 sec · South R L Thornton Freeway
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16
Continue on South R L Thornton Freeway
89.3 mi · 1 hr 32 min · South R L Thornton Freeway
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17
Continue on North Jack Kultgen Expressway
6.6 mi · 8 min · North Jack Kultgen Expressway
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18
Continue on Purple Heart Trail
37.9 mi · 39 min · Purple Heart Trail
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19
Keep slight left
55.8 mi · 59 min
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20
Keep slight left to continue on Purple Heart Trail
49.8 mi · 55 min · Purple Heart Trail
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21
Continue on Interstate Highway 35
1.7 mi · 2 min · Interstate Highway 35
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22
Continue on Purple Heart Trail
11.9 mi · 13 min · Purple Heart Trail
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23
Continue on North Pan Am Expressway
10 mi · 12 min · North Pan Am Expressway
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24
Keep slight left to continue on North Pan Am Expressway
6.4 mi · 8 min · North Pan Am Expressway
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25
Keep slight left to continue on North Pan Am Expressway
2907 ft · 41 sec · North Pan Am Expressway
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26
Take the exit slight right toward Lexington Avenue, Main Avenue, San Pedro Avenue
684 ft · 17 sec
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27
Turn straight onto East Elmira Street
526 ft · 17 sec · East Elmira Street
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28
Turn left onto North Main Avenue
830 ft · 19 sec · North Main Avenue
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29
Enter the roundabout and take exit 2 toward Navarro Street
49 m · 3 sec · Navarro Street
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30
Exit the roundabout onto Navarro Street
34 m · 2 sec · Navarro Street
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31
Keep slight right to continue on North Main Avenue
2181 ft · 52 sec · North Main Avenue
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32
Turn right onto West Travis Street
68 m · 11 sec · West Travis Street
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33
Turn left onto North Flores Street
807 ft · 20 sec · North Flores Street
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34
Continue on Military Plaza
119 m · 16 sec · Military Plaza
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35
Turn left onto Dolorosa Street
100 m · 8 sec · Dolorosa Street
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36
Arrive at your destination
0 m · 1 sec · Dolorosa Street
Car Route Details
A richer read on the saved driving route between Greenville and San Antonio.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
South R L Thornton Freeway
Continue on South R L Thornton Freeway
89.3 mi · 01h 32m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny then Chance Showers And Thunderstorms leaving Greenville and Mostly Sunny near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to San Antonio?
The road trip is about 343.8 miles (553.3 km) and usually takes 05h 03m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Bruceville-Eddy is a useful midpoint, sitting about 162.1 miles from Greenville and 181.8 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 292.7 miles (471 km), while the road route adds roughly 51.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:52 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $45.84 one way or $91.68 round trip. Estimated CO2 is about 107.8 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny then Chance Showers And Thunderstorms around Greenville and Mostly Sunny near San Antonio.
Stop Ideas Near Bruceville-Eddy
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Bruceville-Eddy.
McGregor
Temple
Waco, TX
Killeen, Texas
Flight Path Map
This map shows the direct air route between Greenville and San Antonio. Straight-line distance: 292.65 mi (470.97 km).
#1 Greenville
City in Hunt County, Texas, United States
| Population | 29,374 |
| Coordinates | 33.1384500, -96.1108100 |
| Altitude | 165 |
| Country | United States |
#2 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
End: Dolorosa Street (-98.493645, 29.424163)
Estimated Travel Time
Distance: 553 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 27m |
| 40 mph (64.37 km/h) | 08h 35m |
| 50 mph (80.47 km/h) | 06h 52m |
| 60 mph (96.56 km/h) | 05h 43m |
| 70 mph (112.65 km/h) | 04h 54m |
| 80 mph (129 km/h) | 04h 17m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $45.84 | $91.68 |
| Mid-grade | $4.25 | $51.58 | $103.15 |
| Premium | $4.59 | $55.69 | $111.38 |
| Diesel | $3.99 | $48.44 | $96.87 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · May 26, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.