How far is Greenville, TN from Mount Pleasant, SC?
The driving distance from Greenville, TN to Mount Pleasant, SC is about 568 miles (914.1 km), with a travel time of about 10h 47m by car.
- The straight-line flight distance is about 467.2 miles (751.9 km).
- For a round trip, plan for roughly 21h 34m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CST.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 10h 47m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Haywood County, North Carolina, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Patchy Frost then Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Greenville and Mount Pleasant.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and Mount Pleasant.
-
1
Start on Bernard Road
15 m · 3 sec · Bernard Road
-
2
Turn right onto Clarksville Highway
6.1 mi · 9 min · Clarksville Highway
-
3
Take the ramp slight right toward SR 155 East
1395 ft · 34 sec
-
4
Merge slight left onto Briley Parkway
2.6 mi · 3 min · Briley Parkway
-
5
Take the exit slight right toward I 24 East: Nashville
2799 ft · 1 min
-
6
Merge slight left
2667 ft · 36 sec
-
7
Keep slight right to continue on I 24 East, I 65 South: Nashville
2.3 mi · 3 min
-
8
Continue on I 24 East: Chattanooga, Knoxville
2.8 mi · 4 min
-
9
Keep slight left to continue on I 40 East, I 24 East: Knoxville, Chattanooga
80.6 mi · 1 hr 27 min
-
10
Continue straight
93.2 mi · 1 hr 42 min
-
11
Keep slight left
36.7 mi · 41 min
-
12
Keep slight right to continue on I 40 East: Asheville
76.3 mi · 1 hr 35 min
-
13
Take the exit slight right toward I 26 East, US 74 East, US 64 Truck East: Hendersonville, Spartanburg
22.8 mi · 28 min
-
14
Keep slight left to continue on Andrew Jackson Highway
124.9 mi · 2 hr 18 min · Andrew Jackson Highway
-
15
Keep slight right to continue on Charleston
102.9 mi · 1 hr 53 min
-
16
Take the exit slight right toward Aviation Avenue, Remount Road
1137 ft · 28 sec
-
17
Keep slight left to continue on Remount Road, Hanahan
1865 ft · 46 sec
-
18
Keep slight right to continue on Remount Road, Hanahan
952 ft · 29 sec
-
19
Turn left onto Remount Road
1932 ft · 45 sec · Remount Road
-
20
Turn right onto Rivers Avenue
1.3 km · 1 min · Rivers Avenue
-
21
Take the ramp slight left
1890 ft · 48 sec
-
22
Merge slight left onto Mark Clark Expressway
11.9 mi · 15 min · Mark Clark Expressway
-
23
Continue on Chuck Dawley Boulevard
1.3 mi · 2 min · Chuck Dawley Boulevard
-
24
Turn right onto Coleman Boulevard
72 m · 13 sec · Coleman Boulevard
-
25
Turn left
23 m · 6 sec
-
26
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Greenville and Mount Pleasant.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Andrew Jackson Highway
Keep slight left to continue on Andrew Jackson Highway
125 mi · 02h 18m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Patchy Frost then Sunny leaving Greenville and Sunny near Mount Pleasant.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to Mount Pleasant?
The road trip is about 568 miles (914.1 km) and usually takes 10h 47m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Clyde is a useful midpoint, sitting about 282.9 miles from Greenville and 285.1 miles from Mount Pleasant.
How much longer is the road route than the straight-line distance?
The direct path is about 467.2 miles (751.9 km), while the road route adds roughly 100.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CST. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $73.23 one way or $146.45 round trip. Estimated CO2 is about 178.1 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Greenville and Mount Pleasant, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Patchy Frost then Sunny around Greenville and Sunny near Mount Pleasant.
Stop Ideas Near Clyde
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Clyde.
Greenville
Clemson
Spartanburg
Toccoa
Flight Path Map
This map shows the direct air route between Greenville and Mount Pleasant. Straight-line distance: 467.18 mi (751.86 km).
#1 Greenville
Greenville is a place in Tennessee, United States.
| Population | 0 |
| Coordinates | 36.2970000, -86.8883300 |
| Altitude | 254 |
| Country | United States |
#2 Mount Pleasant
The second most populous city in Charleston County, South Carolina.
| Population | 92,799 |
| Coordinates | 32.7940700, -79.8625900 |
| Altitude | 3 |
| Country | United States |
End: Mount Pleasant (-79.86259, 32.79407)
Estimated Travel Time
Distance: 914 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 18h 55m |
| 40 mph (64.37 km/h) | 14h 12m |
| 50 mph (80.47 km/h) | 11h 21m |
| 60 mph (96.56 km/h) | 09h 27m |
| 70 mph (112.65 km/h) | 08h 06m |
| 80 mph (129 km/h) | 07h 05m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.65 | $73.23 | $146.45 |
| Mid-grade | $4.13 | $82.71 | $165.41 |
| Premium | $4.55 | $91.10 | $182.20 |
| Diesel | $5.88 | $117.74 | $235.47 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · Nov 07, 2026