How far is Greenville, NY from Buffalo, NY?
The driving distance from Greenville, NY to Buffalo, NY is about 287.6 miles (462.9 km), with a travel time of about 04h 54m by car.
- The straight-line flight distance is about 248.9 miles (400.5 km).
- For a round trip, plan for roughly 09h 48m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 54m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Onondaga County, New York
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers Likely
Chance Rain Showers then Chance Snow Showers
Driving Route Map
The map below follows the saved road route between Greenville and Buffalo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and Buffalo.
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1
Start on the route
5 m · 2 sec
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2
Turn right onto State Highway 32
2 mi · 3 min · State Highway 32
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3
Turn left onto County Route 405
1.2 km · 2 min · County Route 405
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4
Turn right onto County Route 401
5.2 mi · 10 min · County Route 401
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5
At the end of the road, turn left
57 m · 5 sec
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6
Turn right onto New York State Highway 143
2.7 mi · 5 min · New York State Highway 143
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7
Turn right onto Delaware Turnpike
3.6 mi · 5 min · Delaware Turnpike
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8
Turn left onto Helderberg Trail
6.9 mi · 11 min · Helderberg Trail
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9
At the end of the road, turn left onto Helderberg Trail
3.3 mi · 6 min · Helderberg Trail
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10
Continue on State Highway 443
7.3 mi · 11 min · State Highway 443
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11
At the end of the road, turn right onto State Highway 30
2.5 mi · 4 min · State Highway 30
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12
Continue on Zicha Road
1.1 mi · 2 min · Zicha Road
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13
Continue on Junction Road
1.2 km · 1 min · Junction Road
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14
Keep slight left to continue on Junction Road
3004 ft · 57 sec · Junction Road
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15
Turn right onto State Highway 30A
1.8 mi · 3 min · State Highway 30A
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16
Continue straight
13.3 mi · 18 min
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17
Turn straight onto State Highway 5S
2.2 mi · 3 min · State Highway 5S
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18
Continue on East Main Street
1236 ft · 29 sec · East Main Street
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19
Take the ramp right
1152 ft · 28 sec
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20
Keep slight left to continue on I 90 West
2172 ft · 53 sec
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21
Merge slight left onto New York State Thruway
227 mi · 4 hr 23 min · New York State Thruway
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22
Take the exit slight right toward NY 33 West: Buffalo
1901 ft · 46 sec
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23
Merge slight left onto Kensington Expressway
6.4 mi · 9 min · Kensington Expressway
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24
Keep slight left to continue on Oak Street
2170 ft · 40 sec
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25
Continue on Oak Street
131 m · 14 sec · Oak Street
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26
Turn right onto Genesee Street
1172 ft · 39 sec · Genesee Street
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27
Turn right onto East Huron Street
729 ft · 34 sec · East Huron Street
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28
Turn left onto Franklin Street
716 ft · 23 sec · Franklin Street
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29
Turn right onto Genesee Street
123 m · 12 sec · Genesee Street
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30
Enter the roundabout toward Niagara Square
119 m · 12 sec · Niagara Square
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31
Arrive at your destination
0 m · 1 sec · Niagara Square
Car Route Details
A richer read on the saved driving route between Greenville and Buffalo.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
New York State Thruway
Merge slight left onto New York State Thruway
227 mi · 04h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Rain Showers Likely leaving Greenville and Chance Rain Showers then Chance Snow Showers near Buffalo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to Buffalo?
The road trip is about 287.6 miles (462.9 km) and usually takes 04h 54m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Galeville is a useful midpoint, sitting about 144.6 miles from Greenville and 143 miles from Buffalo.
How much longer is the road route than the straight-line distance?
The direct path is about 248.9 miles (400.5 km), while the road route adds roughly 38.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:12 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.69 one way or $81.38 round trip. Estimated CO2 is about 90.2 kg one way.
What should you check before leaving?
Before you leave, expect Rain Showers Likely around Greenville and Chance Rain Showers then Chance Snow Showers near Buffalo.
Stop Ideas Near Galeville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall Cafe
Syracuse City Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Galeville.
William F. Walsh Regional Transportation Center
Empire Expo Center
Rome station
Union Station
Flight Path Map
This map shows the direct air route between Greenville and Buffalo. Straight-line distance: 248.89 mi (400.55 km).
#1 Greenville
Town in Greene County, New York, United States
| Population | 4,668 |
| Coordinates | 42.4153600, -74.0220800 |
| Altitude | 216 |
| Country | United States |
#2 Buffalo
The second most populous city in New York.
| Population | 254,479 |
| Coordinates | 42.8864500, -78.8783700 |
| Altitude | 183 |
| Country | United States |
End: Niagara Square (-78.878786, 42.886515)
Estimated Travel Time
Distance: 463 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 34m |
| 40 mph (64.37 km/h) | 07h 11m |
| 50 mph (80.47 km/h) | 05h 45m |
| 60 mph (96.56 km/h) | 04h 47m |
| 70 mph (112.65 km/h) | 04h 06m |
| 80 mph (129 km/h) | 03h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $40.69 | $81.38 |
| Mid-grade | $4.48 | $45.48 | $90.96 |
| Premium | $4.86 | $49.34 | $98.68 |
| Diesel | $4.69 | $47.64 | $95.29 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.