How far is Buffalo, NY from Greenville, NY?

The driving distance from Buffalo, NY to Greenville, NY is about 290.1 miles (466.9 km), with a travel time of about 06h 01m by car.

  • The straight-line flight distance is about 248.9 miles (400.5 km).
  • For a round trip, plan for roughly 12h 02m of driving time before adding stops, traffic, or weather delays.
  • A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Trip Tools

Reverse, save, or send this route

This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.

Reverse Route
Quick Snapshot
Road
290.09 mi
06h 01m
Flight
248.89 mi
400.55 km direct

This drive is better planned with a longer stop or an overnight stay.

Learn Distance

Choose another destination from Buffalo.

Flight Distance

Direct air line
248.89 mi
Kilometers
400.55 km
Flight Time
00h 30m

Driving Distance

Road route
290.09 mi
Kilometers
466.86 km
Drive Time
06h 01m

Gas Cost Calculator

Leave and Arrive Planner

Pick a departure time to see your estimated arrival and same-day return window.

Drive time stays fixed at 06h 01m.

Arrival Snapshot
Arrive in Greenville
Sun, Apr 19, 12:54 PM EDT
Return by in Buffalo
Sun, Apr 19, 6:56 PM EDT
Useful when you're deciding between a quick errand, a day trip, or a longer stop.
Leave Buffalo
2026-04-19T06:53
Arrive Greenville
Sun, Apr 19, 12:54 PM EDT
Route Timing
06h 01m
One way by road
Best Departure Window
6:00 AM to 7:30 AM EDT
Treat this as a longer travel day
Arrive between
12:01 PM to 1:31 PM EDT

Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.

Leave by
11:58 PM EDT
Keeps a same-day return open with about 08h 00m at the destination.
Back in Buffalo
8:00 PM EDT
Overnight-style route

This departure sits inside the recommended comfort window for the route.

Halfway Point

A useful midpoint for breaks, coffee, or meeting in the middle.

Mid-route stop
Liverpool
NY

Village in Onondaga County, New York, United States

From Buffalo
144.8 mi
03h 00m
To Greenville
145.3 mi
03h 00m

Route Weather Snapshot

Check the forecast at both ends before you head out.

Origin
43°F
Sunday

Chance Rain Showers then Chance Snow Showers

Starts
Sun, Apr 19 6:00 AM EDT
Wind
12 to 15 mph W
Destination
59°F
Sunday

Rain Showers Likely

Starts
Sun, Apr 19 6:00 AM EDT
Wind
3 to 7 mph W

Driving Route Map

The map below follows the saved road route between Buffalo and Greenville.

Turn-by-Turn Driving Directions

Step-by-step road directions between Buffalo and Greenville.

  1. 1

    Start on Niagara Square

    562 ft · 19 sec · Niagara Square

  2. 2

    Exit the rotary onto Court Street

    809 ft · 27 sec · Court Street

  3. 3

    Continue on Lafayette Square

    114 m · 18 sec · Lafayette Square

  4. 4

    Turn left onto Washington Street

    1309 ft · 45 sec · Washington Street

  5. 5

    Turn right onto Genesee Street

    1429 ft · 49 sec · Genesee Street

  6. 6

    Turn left onto Elm Street

    80 m · 8 sec · Elm Street

  7. 7

    Take the exit straight toward NY 33 East

    972 ft · 15 sec

  8. 8

    Continue on Kensington Expressway

    6.8 mi · 9 min · Kensington Expressway

  9. 9

    Take the exit slight right toward I 90 East: Niagara Falls, Albany

    1644 ft · 46 sec

  10. 10

    Merge slight left onto New York State Thruway

    227.2 mi · 4 hr 23 min · New York State Thruway

  11. 11

    Take the exit slight right toward NY 10: Canajoharie, Sharon Springs

    2504 ft · 1 min

  12. 12

    At the end of the road, turn left onto East Main Street

    1236 ft · 27 sec · East Main Street

  13. 13

    Continue on State Highway 5S

    2.2 mi · 3 min · State Highway 5S

  14. 14

    Keep slight right

    15.1 mi · 21 min

  15. 15

    Turn left onto Junction Road

    1.3 mi · 2 min · Junction Road

  16. 16

    Continue on Zicha Road

    1.1 mi · 2 min · Zicha Road

  17. 17

    Continue on State Highway 30A

    2.5 mi · 4 min · State Highway 30A

  18. 18

    Turn left onto State Highway 443

    4.2 mi · 6 min · State Highway 443

  19. 19

    Keep slight right to continue on State Highway 443

    3.1 mi · 4 min · State Highway 443

  20. 20

    Continue on Helderberg Trail

    3.3 mi · 6 min · Helderberg Trail

  21. 21

    Continue on Helderberg Trail

    6.9 mi · 11 min · Helderberg Trail

  22. 22

    Turn right onto Delaware Turnpike

    3.6 mi · 5 min · Delaware Turnpike

  23. 23

    Turn left onto New York State Highway 143

    2.7 mi · 5 min · New York State Highway 143

  24. 24

    At the end of the road, turn left

    57 m · 6 sec

  25. 25

    Turn right onto County Route 401

    5.2 mi · 10 min · County Route 401

  26. 26

    At the end of the road, turn left onto County Route 405

    1.2 km · 2 min · County Route 405

  27. 27

    Turn right onto State Highway 32

    2 mi · 3 min · State Highway 32

  28. 28

    Turn left

    5 m · 1 sec

  29. 29

    Arrive at your destination

    0 m · 1 sec

Car Route Details

A richer read on the saved driving route between Buffalo and Greenville.

OSRM road route
Drive Character

Interchange-aware route

The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.

Directions
29 steps
14 turns on the saved route
Ramps & Exits
5
1 merges, 4 ramps or exits
Navigation Density
10 / 100 mi
Decision points by distance
Main Roads
New York State Thruway
227 mi · 78%
State Highway 5S
17.3 mi · 6%
Helderberg Trail
10.2 mi · 4%
State Highway 443
7.32 mi · 3%
Kensington Expressway
6.81 mi · 2%
County Route 401
5.21 mi · 2%
Longest Stretch

New York State Thruway

Merge slight left onto New York State Thruway

227 mi · 04h 23m

Route Summary

A quick read on whether this route feels easy, ambitious, or worth planning around.

Trip Read

Better with a longer stop

This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.

Drive Time
06h 01m
Overnight route
Same-Day Return
12h 02m
Round-trip wheel time
Road vs Air
+41.2 mi
248.9 mi direct line
Halfway Stop
Liverpool
03h 00m from Buffalo
Leave By
11:58 PM EDT
Overnight-style route
Weather Watch

Chance Rain Showers then Chance Snow Showers leaving Buffalo and Rain Showers Likely near Greenville.

Trip Questions

Direct answers travelers usually want before committing to the drive.

How long does it take to drive from Buffalo to Greenville?

The road trip is about 290.1 miles (466.9 km) and usually takes 06h 01m in normal driving conditions.

Is this a same-day trip or an overnight route?

This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.

What is the halfway point on this route?

Liverpool is a useful midpoint, sitting about 144.8 miles from Buffalo and 145.3 miles from Greenville.

How much longer is the road route than the straight-line distance?

The direct path is about 248.9 miles (400.5 km), while the road route adds roughly 41.2 extra miles because roads do not follow the straight air line.

When is the best time to leave for this route?

A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.

How much will gas cost for this route?

Using about 28.3 MPG, regular gas is estimated at $41.05 one way or $82.10 round trip. Estimated CO2 is about 91 kg one way.

What should you check before leaving?

Before you leave, expect Chance Rain Showers then Chance Snow Showers around Buffalo and Rain Showers Likely near Greenville.

Stop Ideas Near Liverpool

Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.

Mid-route Guidance
These suggestions come from reviewed places and nearby services around Liverpool and the surrounding midpoint area.
City Hall Cafe
Coffee break 4.7 mi away

City Hall Cafe

Syracuse , NY
300 S State St, Syracuse, NY 13202
Rating 4.6/5 32 reviews Coffee shop
Syracuse City Hall
Meeting point 4.6 mi away

Syracuse City Hall

Syracuse , NY
233 E Washington St, Syracuse, NY 13202
Rating 4.0/5 26 reviews City Hall

Transit and Meeting Points

Useful pickup, handoff, or rendezvous points close to Liverpool.

RAIL

Empire Expo Center

4 mi away
581 State Fair Blvd
RAIL

William F. Walsh Regional Transportation Center

6 mi away
131 Alliance Bank Parkway
RAIL

Rome station

63 mi away
6599 Martin Street
RAIL

Union Station

81 mi away
321 Main St.

Flight Path Map

This map shows the direct air route between Buffalo and Greenville. Straight-line distance: 248.89 mi (400.55 km).

Buffalo

#1 Buffalo

The second most populous city in New York.

Population254,479
Coordinates42.8864500, -78.8783700
Altitude183
CountryUnited States
Greenville

#2 Greenville

Town in Greene County, New York, United States

Population4,668
Coordinates42.4153600, -74.0220800
Altitude216
CountryUnited States
Start: Buffalo (-78.87837, 42.88645)
End: Greenville (-74.02208, 42.41536)

Estimated Travel Time

Distance: 467 km by road

SpeedTime
30 mph (48.3 km/h)09h 39m
40 mph (64.37 km/h)07h 15m
50 mph (80.47 km/h)05h 48m
60 mph (96.56 km/h)04h 50m
70 mph (112.65 km/h)04h 08m
80 mph (129 km/h)03h 37m

Fuel, Round Trip and CO2

Estimated fuel cost and emissions for this route.

One-way fuel
10.24 gal
38.75 L · about $41.05
Round trip
$82.10
20.48 gal · 77.5 L
Estimated CO2
91 kg one way
Round trip: 182 kg / 401 lb CO2, using regular gasoline.
Fuel$/galOne wayRound trip
Regular gas $4.01 $41.05 $82.10
Mid-grade $4.48 $45.89 $91.77
Premium $4.86 $49.78 $99.55
Diesel $4.69 $48.07 $96.13

Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.

Prices in New York · Apr 19, 2026

There is no time difference between Buffalo and Greenville. The current time is 06:53:17.

Distance to Other Cities

Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.

How did we calculate? Place names are translated into coordinates. The Haversine formula calculates straight-line distance; driving distance uses road network data.