How far is Glendale, MO from Cape Girardeau, MO?
The driving distance from Glendale, MO to Cape Girardeau, MO is about 81.3 miles (130.9 km), with a travel time of about 01h 33m by car.
- The straight-line flight distance is about 65.4 miles (105.3 km).
- For a round trip, plan for roughly 03h 06m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 33m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in New Madrid County, Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Glendale and Cape Girardeau.
Turn-by-Turn Driving Directions
Step-by-step road directions between Glendale and Cape Girardeau.
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1
Start on the route
2310 ft · 1 min
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2
Continue on County Road 282
1 mi · 4 min · County Road 282
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3
Turn left onto County Road 281
1.7 mi · 7 min · County Road 281
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4
Continue on County Road 277
1.1 mi · 4 min · County Road 277
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5
Turn right
9.8 mi · 17 min
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6
At the end of the road, turn right
1 mi · 2 min
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7
Turn left
1.1 km · 1 min
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8
Take the ramp left toward I 55 North: Sikeston
1007 ft · 25 sec
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9
Merge slight left
60.5 mi · 1 hr 5 min
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10
Keep slight right to continue on US 61, I 55 Business: Cape Girardeau
2 mi · 3 min
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11
Turn right onto Shawnee Parkway
1.6 mi · 3 min · Shawnee Parkway
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12
Turn left onto South Sprigg Street
1.3 km · 2 min · South Sprigg Street
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13
Turn right onto Broadway Street
2497 ft · 51 sec · Broadway Street
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14
Arrive at your destination
0 m · 1 sec · Broadway Street
Car Route Details
A richer read on the saved driving route between Glendale and Cape Girardeau.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 North
Merge slight left
60.5 mi · 01h 05m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Glendale and Sunny near Cape Girardeau.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Glendale to Cape Girardeau?
The road trip is about 81.3 miles (130.9 km) and usually takes 01h 33m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Matthews is a useful midpoint, sitting about 40.7 miles from Glendale and 40.6 miles from Cape Girardeau.
How much longer is the road route than the straight-line distance?
The direct path is about 65.4 miles (105.3 km), while the road route adds roughly 15.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 3:24 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $10.82 one way or $21.65 round trip. Estimated CO2 is about 25.5 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Glendale and Sunny near Cape Girardeau.
Stop Ideas Near Matthews
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Matthews.
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Flight Path Map
This map shows the direct air route between Glendale and Cape Girardeau. Straight-line distance: 65.46 mi (105.35 km).
#1 Glendale
City in Missouri
| Population | 5,863 |
| Coordinates | 36.4106200, -89.9056400 |
| Altitude | 82 |
| Country | United States |
#2 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
End: Broadway Street (-89.518146, 37.305904)
Estimated Travel Time
Distance: 131 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 02h 42m |
| 40 mph (64.37 km/h) | 02h 01m |
| 50 mph (80.47 km/h) | 01h 37m |
| 60 mph (96.56 km/h) | 01h 21m |
| 70 mph (112.65 km/h) | 01h 09m |
| 80 mph (129 km/h) | 01h 00m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $10.82 | $21.65 |
| Mid-grade | $4.25 | $12.21 | $24.41 |
| Premium | $4.65 | $13.36 | $26.71 |
| Diesel | $5.30 | $15.22 | $30.44 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.