How far is Gainesville, FL from Port Salerno, FL?
The driving distance from Gainesville, FL to Port Salerno, FL is about 241 miles (387.9 km), with a travel time of about 04h 31m by car.
- The straight-line flight distance is about 216.1 miles (347.7 km).
- For a round trip, plan for roughly 09h 02m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 31m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
A city in Osceola County, Florida.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Areas Of Fog then Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Gainesville and Port Salerno.
Turn-by-Turn Driving Directions
Step-by-step road directions between Gainesville and Port Salerno.
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1
Start on South Main Street
2510 ft · 1 min · South Main Street
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2
Enter the roundabout and take exit 2 toward South Main Street
45 m · 3 sec · South Main Street
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3
Exit the roundabout onto South Main Street
1332 ft · 33 sec · South Main Street
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4
Enter the roundabout and take exit 1 toward South Main Street
18 m · 1 sec · South Main Street
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5
Exit the roundabout onto South Main Street
1.6 mi · 3 min · South Main Street
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6
Turn right onto Southwest Williston Road
2572 ft · 54 sec · Southwest Williston Road
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7
Turn left onto South Main Street
807 ft · 23 sec · South Main Street
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8
Turn straight
2000 ft · 34 sec
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9
Continue straight
7 mi · 8 min
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10
Continue straight
3212 ft · 47 sec
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11
Turn right onto Southeast County Road 234
1.4 mi · 3 min · Southeast County Road 234
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12
Take the ramp left toward I 75 South: Tampa
1148 ft · 28 sec
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13
Merge slight left
46.2 mi · 50 min
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14
Take the exit slight left toward Florida's Turnpike South, Orlando
174.1 mi · 3 hr 7 min · Florida's Turnpike
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15
Take the exit slight right toward FL 714: Stuart
1.1 km · 2 min
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16
Turn right onto Southwest Martin Highway
3.4 mi · 7 min · Southwest Martin Highway
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17
Continue on Southeast Indian Street
1.3 mi · 2 min · Southeast Indian Street
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18
Turn right onto Southeast Federal Highway
2 mi · 4 min · Southeast Federal Highway
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19
Turn left onto Southeast Salerno Road
1.1 km · 2 min · Southeast Salerno Road
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20
Arrive at your destination
0 m · 1 sec · Southeast Salerno Road
Car Route Details
A richer read on the saved driving route between Gainesville and Port Salerno.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Florida's Turnpike
Take the exit slight left toward Florida's Turnpike South, Orlando
174 mi · 03h 07m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Areas Of Fog then Sunny leaving Gainesville and Mostly Sunny near Port Salerno.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Gainesville to Port Salerno?
The road trip is about 241 miles (387.9 km) and usually takes 04h 31m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Kissimmee is a useful midpoint, sitting about 120.7 miles from Gainesville and 120.4 miles from Port Salerno.
How much longer is the road route than the straight-line distance?
The direct path is about 216.1 miles (347.7 km), while the road route adds roughly 24.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:58 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.26 one way or $70.52 round trip. Estimated CO2 is about 75.5 kg one way.
What should you check before leaving?
Before you leave, expect Areas Of Fog then Sunny around Gainesville and Mostly Sunny near Port Salerno.
Stop Ideas Near Kissimmee
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall
St. Cloud City Hall
Celebration Town Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Kissimmee.
Kissimmee
Orlando Health/Amtrak
Winter Park
Winter Haven
Flight Path Map
This map shows the direct air route between Gainesville and Port Salerno. Straight-line distance: 216.05 mi (347.7 km).
#1 Gainesville
The third most populous city in Florida.
| Population | 135,004 |
| Coordinates | 29.6516300, -82.3248300 |
| Altitude | 54 |
| Country | United States |
#2 Port Salerno
Census-designated place in Martin County, Florida
| Population | 10,091 |
| Coordinates | 27.1442200, -80.2006000 |
| Altitude | 4 |
| Country | United States |
End: Port Salerno (-80.2006, 27.14422)
Estimated Travel Time
Distance: 388 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 01m |
| 40 mph (64.37 km/h) | 06h 01m |
| 50 mph (80.47 km/h) | 04h 49m |
| 60 mph (96.56 km/h) | 04h 01m |
| 70 mph (112.65 km/h) | 03h 26m |
| 80 mph (129 km/h) | 03h 00m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $35.26 | $70.52 |
| Mid-grade | $4.60 | $39.07 | $78.13 |
| Premium | $4.90 | $41.62 | $83.23 |
| Diesel | $4.35 | $36.97 | $73.95 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 16, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.