How far is East Prairie, MO from St. Louis, MO?
The driving distance from East Prairie, MO to St. Louis, MO is about 159.9 miles (257.3 km), with a travel time of about 02h 31m by car.
- The straight-line flight distance is about 135.1 miles (217.5 km).
- For a round trip, plan for roughly 05h 02m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 31m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between East Prairie and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Prairie and St. Louis.
-
1
Start on East Main Street
26 m · 6 sec · East Main Street
-
2
Turn right onto North Washington Street
1650 ft · 34 sec · North Washington Street
-
3
Turn right
9.5 mi · 13 min
-
4
Take the ramp sharp left
1236 ft · 30 sec
-
5
Merge slight left
10 mi · 11 min
-
6
Take the exit slight right toward I 55 North: Saint Louis
1987 ft · 48 sec
-
7
Merge slight left
27.1 mi · 29 min
-
8
Keep slight left
101.5 mi · 1 hr 49 min
-
9
Continue on Rosa Parks Highway
12.5 mi · 16 min · Rosa Parks Highway
-
10
Take the exit slight right toward MO 30 East: Gravois Avenue
1001 ft · 24 sec
-
11
Turn slight right onto Gravois Avenue
1044 ft · 27 sec · Gravois Avenue
-
12
Continue on South Tucker Boulevard
1.3 mi · 3 min · South Tucker Boulevard
-
13
Turn right onto Market Street
26 m · 2 sec · Market Street
-
14
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between East Prairie and St. Louis.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 North
Keep slight left
102 mi · 01h 49m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving East Prairie and Sunny near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from East Prairie to St. Louis?
The road trip is about 159.9 miles (257.3 km) and usually takes 02h 31m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Perryville is a useful midpoint, sitting about 81.7 miles from East Prairie and 78.2 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 135.1 miles (217.5 km), while the road route adds roughly 24.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:28 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $21.27 one way or $42.54 round trip. Estimated CO2 is about 50.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around East Prairie and Sunny near St. Louis.
Stop Ideas Near Perryville
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Perryville.
Carbondale station
Du Quoin
Marion, IL
Vienna, IL
Flight Path Map
This map shows the direct air route between East Prairie and St. Louis. Straight-line distance: 135.15 mi (217.5 km).
#1 East Prairie
City in Mississippi County, Missouri, United States
| Population | 2,924 |
| Coordinates | 36.7797800, -89.3856300 |
| Altitude | 93 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 257 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 19m |
| 40 mph (64.37 km/h) | 03h 59m |
| 50 mph (80.47 km/h) | 03h 11m |
| 60 mph (96.56 km/h) | 02h 39m |
| 70 mph (112.65 km/h) | 02h 17m |
| 80 mph (129 km/h) | 01h 59m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $21.27 | $42.54 |
| Mid-grade | $4.25 | $23.99 | $47.97 |
| Premium | $4.65 | $26.25 | $52.50 |
| Diesel | $5.30 | $29.91 | $59.83 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.