How far is East Palo Alto, CA from San Diego, CA?
The driving distance from East Palo Alto, CA to San Diego, CA is about 483.1 miles (777.5 km), with a travel time of about 07h 57m by car.
- The straight-line flight distance is about 432.3 miles (695.7 km).
- For a round trip, plan for roughly 15h 54m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM PDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 57m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Place in Kern County California
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between East Palo Alto and San Diego.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Palo Alto and San Diego.
-
1
Start on University Avenue
1160 ft · 48 sec · University Avenue
-
2
Continue on University Avenue
1.5 km · 3 min · University Avenue
-
3
Turn left onto US 101 South: San Jose
1523 ft · 41 sec
-
4
Merge slight left onto Bayshore Freeway
4.7 mi · 5 min · Bayshore Freeway
-
5
Keep slight left to continue on Bayshore Freeway
42.4 mi · 49 min · Bayshore Freeway
-
6
Take the exit slight right toward CA 152 East: 10th Street, Pacheco Pass Road
1539 ft · 40 sec
-
7
Turn left onto East 10th Street
108 m · 13 sec · East 10th Street
-
8
Continue on Pacheco Pass Highway
40.6 mi · 50 min · Pacheco Pass Highway
-
9
Take the exit slight right toward I 5: Los Angeles
3148 ft · 1 min
-
10
Merge slight left onto Westside Freeway
181.1 mi · 3 hr 14 min · Westside Freeway
-
11
Keep slight right
58.4 mi · 1 hr 7 min
-
12
Keep slight left to continue on Golden State Freeway
4.1 mi · 5 min · Golden State Freeway
-
13
Keep slight right to continue on I 405 South
1354 ft · 18 sec
-
14
Keep slight left
24.7 mi · 29 min
-
15
Keep slight left to continue on Golden State Freeway
1.3 mi · 2 min · Golden State Freeway
-
16
Merge slight left onto Santa Ana Freeway
25.7 mi · 30 min · Santa Ana Freeway
-
17
Keep slight right to continue on Santa Ana Freeway
1241 ft · 16 sec · Santa Ana Freeway
-
18
Take the exit slight right toward Broadway, Main Street, Santa Ana
1.3 km · 57 sec
-
19
Keep slight left
788 ft · 10 sec
-
20
Keep slight left to continue on I 5 South
981 ft · 13 sec
-
21
Merge slight left onto Santa Ana Freeway
1.3 km · 54 sec · Santa Ana Freeway
-
22
Keep slight right to continue on Santa Ana Freeway
1.2 km · 52 sec · Santa Ana Freeway
-
23
Keep slight right to continue on Santa Ana Freeway
1.2 mi · 1 min · Santa Ana Freeway
-
24
Take the exit slight right toward Newport Avenue
1.2 km · 1 min
-
25
Turn right onto Newport Avenue
1943 ft · 44 sec · Newport Avenue
-
26
Turn left onto Walnut Avenue
2.2 mi · 4 min · Walnut Avenue
-
27
Turn left onto Jamboree Road
2595 ft · 38 sec · Jamboree Road
-
28
Take the exit slight right toward I 5 South
1479 ft · 21 sec
-
29
Merge slight left onto Santa Ana Freeway
5.5 mi · 6 min · Santa Ana Freeway
-
30
Keep slight left to continue on Santa Ana Freeway
1.3 km · 56 sec · Santa Ana Freeway
-
31
Merge slight right onto San Diego Freeway
76.5 mi · 1 hr 29 min · San Diego Freeway
-
32
Take the exit slight right toward Front Street, Civic Center, 2nd Avenue
1164 ft · 28 sec
-
33
Keep slight right to continue on Front Street, Civic Center
592 ft · 15 sec
-
34
Continue on Front Street
2662 ft · 2 min · Front Street
-
35
Arrive at your destination
0 m · 1 sec · Front Street
Car Route Details
A richer read on the saved driving route between East Palo Alto and San Diego.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Westside Freeway
Merge slight left onto Westside Freeway
181 mi · 03h 14m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving East Palo Alto and Mostly Sunny near San Diego.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from East Palo Alto to San Diego?
The road trip is about 483.1 miles (777.5 km) and usually takes 07h 57m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Buttonwillow is a useful midpoint, sitting about 238.9 miles from East Palo Alto and 244.3 miles from San Diego.
How much longer is the road route than the straight-line distance?
The direct path is about 432.3 miles (695.7 km), while the road route adds roughly 50.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM PDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $98.36 one way or $196.72 round trip. Estimated CO2 is about 151.5 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around East Palo Alto and Mostly Sunny near San Diego.
Stop Ideas Near Buttonwillow
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Buttonwillow.
Wasco station
Bakersfield
Corcoran station
Kettleman City, California
Flight Path Map
This map shows the direct air route between East Palo Alto and San Diego. Straight-line distance: 432.29 mi (695.7 km).
#1 East Palo Alto
City in San Mateo County, California, United States
| Population | 29,059 |
| Coordinates | 37.4688300, -122.1410800 |
| Altitude | 6 |
| Country | United States |
#2 San Diego
The eighth most populous city in the United States and the center of the San Diego metropolitan area.
| Population | 1,422,420 |
| Coordinates | 32.7157100, -117.1647200 |
| Altitude | 20 |
| Country | United States |
End: Front Street (-117.164717, 32.71571)
Estimated Travel Time
Distance: 778 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 16h 05m |
| 40 mph (64.37 km/h) | 12h 04m |
| 50 mph (80.47 km/h) | 09h 39m |
| 60 mph (96.56 km/h) | 08h 03m |
| 70 mph (112.65 km/h) | 06h 54m |
| 80 mph (129 km/h) | 06h 01m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $5.77 | $98.36 | $196.72 |
| Mid-grade | $6.07 | $103.43 | $206.85 |
| Premium | $6.24 | $106.44 | $212.89 |
| Diesel | $7.57 | $129.02 | $258.03 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in California · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.