How far is East Independence, MO from Hannibal, MO?
The driving distance from East Independence, MO to Hannibal, MO is about 207.8 miles (334.4 km), with a travel time of about 04h 08m by car.
- The straight-line flight distance is about 165.5 miles (266.3 km).
- For a round trip, plan for roughly 08h 16m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 08m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Linn County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between East Independence and Hannibal.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Independence and Hannibal.
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1
Start on East 9th Street South
24 m · 9 sec · East 9th Street South
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2
Turn left onto Main Road
1341 ft · 1 min · Main Road
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3
Turn right onto East Truman Road
1.1 mi · 2 min · East Truman Road
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4
Take the ramp slight right
2081 ft · 57 sec
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5
Merge slight left
9.9 mi · 14 min
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6
Turn slight right
125 m · 8 sec
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7
Turn slight right onto South Leonard Street
3174 ft · 2 min · South Leonard Street
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8
Continue on Lightburne Street
2.8 mi · 5 min · Lightburne Street
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9
Take the ramp slight right
1867 ft · 46 sec
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10
Merge slight left onto Chicago-Kansas City Expressway
33.7 mi · 36 min · Chicago-Kansas City Expressway
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11
Take the exit slight right toward US 36, MO 110 East, I 35 Business: Cameron, Hamilton
1213 ft · 33 sec
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12
Turn right onto Chicago-Kansas City Expressway
148.6 mi · 2 hr 52 min · Chicago-Kansas City Expressway
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13
Continue on V.F.W. Memorial Highway
8.3 mi · 10 min · V.F.W. Memorial Highway
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14
Take the exit slight right toward MO 79: Downtown Hannibal, Louisiana
1356 ft · 33 sec
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15
Turn right onto Harrison Hill Road
527 ft · 13 sec · Harrison Hill Road
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16
Continue on Mark Twain Avenue
1.1 km · 1 min · Mark Twain Avenue
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17
Continue on North 3rd Street
1532 ft · 56 sec · North 3rd Street
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18
Turn right onto Broadway
550 ft · 18 sec · Broadway
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19
Turn left
17 m · 4 sec
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20
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between East Independence and Hannibal.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Chicago-Kansas City Expressway
Turn right onto Chicago-Kansas City Expressway
149 mi · 02h 52m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving East Independence and Mostly Sunny near Hannibal.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from East Independence to Hannibal?
The road trip is about 207.8 miles (334.4 km) and usually takes 04h 08m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Laclede is a useful midpoint, sitting about 103.8 miles from East Independence and 104 miles from Hannibal.
How much longer is the road route than the straight-line distance?
The direct path is about 165.5 miles (266.3 km), while the road route adds roughly 42.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:44 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.64 one way or $55.28 round trip. Estimated CO2 is about 65.1 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around East Independence and Mostly Sunny near Hannibal.
Stop Ideas Near Laclede
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Laclede.
La Plata
Flight Path Map
This map shows the direct air route between East Independence and Hannibal. Straight-line distance: 165.49 mi (266.33 km).
#1 East Independence
A census-designated place in Jackson County, Missouri.
| Population | 110,675 |
| Coordinates | 39.0955600, -94.3552300 |
| Altitude | 256 |
| Country | United States |
#2 Hannibal
City in Missouri, USA
| Population | 17,246 |
| Coordinates | 39.7083800, -91.3584800 |
| Altitude | 153 |
| Country | United States |
End: Hannibal (-91.35848, 39.70838)
Estimated Travel Time
Distance: 334 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 55m |
| 40 mph (64.37 km/h) | 05h 11m |
| 50 mph (80.47 km/h) | 04h 09m |
| 60 mph (96.56 km/h) | 03h 27m |
| 70 mph (112.65 km/h) | 02h 58m |
| 80 mph (129 km/h) | 02h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $27.64 | $55.28 |
| Mid-grade | $4.25 | $31.17 | $62.35 |
| Premium | $4.65 | $34.11 | $68.23 |
| Diesel | $5.30 | $38.88 | $77.76 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 01, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.